Publications

Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer’s disease

Cell Stem Cell; https://doi.org/10.1016/j.stem.2021.05.001

A blood-based diagnostic test incorporating plasma Aβ42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity analysis

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition

Streamlined alpha-synuclein RT-QuIC assay for various biospecimens in Parkinson’s disease and dementia with Lewy bodies

Mural cell dysfunction leads to altered cerebrovascular tau uptake following repetitive head trauma

ScienceDirect; https://doi.org/10.1016/j.nbd.2020.105237

Modeling the Inhibition Kinetics of Curcumin, Orange G, and Resveratrol with Amyloid-β Peptide

Multiple sclerosis risk gene Mertk is required for microglial activation and subsequent remyelination

Cell Reports; https://doi.org/10.1016/j.celrep.2021.108835

Extract from the Marine Seaweed Padina pavonica Protects Mitochondrial Biomembranes from Damage by Amyloidogenic Peptides

Protecting P-glycoprotein at the blood–brain barrier from degradation in an Alzheimer’s disease mouse model

Oligomeric Aβ1-42 Induces an AMD-Like Phenotype and Accumulates in Lysosomes to Impair RPE Function

Cells; https://doi.org/10.3390/cells10020413

In vitro comparison of major memory-support dietary supplements for their effectiveness in reduction/inhibition of beta-amyloid protein fibrils and tau protein tangles: key primary targets for memory loss

Scientific Reports; DOI https://doi.org/10.1038/s41598-020-79275-1

Structure-Guided Design, Synthesis, and Evaluation of 1-Indanone and 1,3-Indandione Derivatives as Ligands for Misfolded α-Synuclein Aggregates

ChemRxiv; DOI: 10.26434/chemrxiv.13817243.v1 

Tau-proximity ligation assay reveals extensive previously undetected pathology prior to neurofibrillary tangles in preclinical Alzheimer’s disease

Acta Neuropathologica Communications; https://doi.org/10.1186/s40478-020-01117-y

Inhibition of matrix metalloproteinase-9 secretion by dimethyl sulfoxide and cyclic adenosine monophosphate in human monocytes Denner DR, Udan-Johns ML, Nichols MR. Inhibition of matrix metalloproteinase-9 secretion by dimethyl sulfoxide and cyclic adenosine monophosphate in human monocytes. World J Biol Chem 2021; 12(1): 1-14 [PMID: 33552397 DOI: 10.4331/wjbc.v12.i1.1]

World Journal of Biological Chemistry; doi: 10.4331/wjbc.v12.i1.1

Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on β-amyloid aggregation

ScienceDirect; https://doi.org/10.1016/j.cbi.2020.109300

Inhibition of Amyloid β-Induced Lipid Membrane Permeation and Amyloid β Aggregation by K162

Sigma-2 receptor antagonists rescue neuronal dysfunction induced by Parkinson’s patient brain-derived α-synuclein

Journal of Neuroscience Research; https://doi.org/10.1002/jnr.24782

Pseudopeptide Amyloid Aggregation Inhibitors: In Silico, Single Molecule and Cell Viability Studies

Plasma metabolomics of presymptomatic PSEN1-H163Y mutation carriers: a pilot study

Annals of Clinical and Translational Neurology; https://doi.org/10.1002/acn3.51296

Retinal ganglion cell loss and gliosis in the retinofugal projection following intravitreal exposure to amyloid-beta

ScienceDirect; https://doi.org/10.1016/j.nbd.2020.105146