Publications
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Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs
Stem Cell Reports (2019), (Vol. 13 j 684–699). DOI: 10.1016/j.stemcr.2019.08.011
Nakamura, M., Shiozawa, S.,Tsuboi, D. et al. (2025) -
Synthesis and evaluation of symmetric (1,4-diazepane-1,4-diyl)bis(phenylmethanone) derivatives as amyloid-beta aggregation inhibitors
Med Chem Res (2025). DOI: 10.1007/s00044-025-03512-3
Karuturi, R., Hefny, A., Zhao, Y. et al. (2025) -
Relationship between efficacy and preferential targeting of soluble Aβ aggregates
Alzheimer’s Association (2025), (Vol 11, Issue 4). DOI: 10.1002/trc2.70184
Kaplan, J., Gibbs, E., Coutts, J. et al. (2025) -
Protocol for in vitro phagocytosis assay for primary mouse microglia and human embryonic stem cell-derived microglia
STAR Protocols (2025), (Vol 6, Issue 4). DOI: 10.1016/j.xpro.2025.104219.
Zhu, B., Thurber, A., Piao, X. et al. (2025) -
The Alzheimer’s therapeutic Lecanemab attenuates Aβ pathology by inducing an amyloid-clearing program in microglia
Nat Neurosci (2025). DOI: 10.1038/s41593-025-02125-8
Albertini, G., Zielonka, M., Cuypers, ML. et al. (2025) -
Targeting of amyloid peptide fibers, a biomarker of Alzheimer’s disease, by designing specifically functionalized Iron Oxide Nanoparticles
HAL. (2025), 8 (43), pp.20822-20834. DOI:10.1021/acsanm.5c03459
Porras G., Brison A., Becker A. et al. (2025) -
Role of P-glycoprotein in attenuation of retinal amyloid-β peptide (1–40) clearance across the rat inner blood-retinal barrier induced by lipopolysaccharide
Science Direct (2025), 262. DOI: 10.1016/j.exer.2025.110759.
Kiyotaka D., Shin-ichi A., Yuma T. et al. (2025) -
Peptidomimetics Based on C-Terminus of Blm10 Stimulate Human 20S Proteasome Activity and Promote Degradation of Proteins
Biomolecules (2022), 12, 777. DOI: 10.3390/biom12060777
Cekała, K., Trepczyk, K., Sowik, D. et al. (2025) -
Detection of extracellular amyloid beta aggregates by an Aducanumab-based synNotch receptor: an in vitro proof-of-concept study
J Transl Med 23, 1255 (2025). DOI: 10.1186/s12967-025-07324-2
Bergo, N., Lee, S., Siebrand, C. et al. (2025) -
Inhibitory Effect of Insulin-Degrading Enzyme-Selective Inhibitor, Ii1, on the Elimination of Amyloid-β(1-40) from Rat Brain
Biol. Pharm. Bull. 48, 1700–1707 (2025). DOI: 10.1248/bpb.b25-00424
Takeshi, S., & Sumio, O. (2025) -
Cell-type-specific dysregulation of mitochondrial calcium signaling in Alzheimer’s disease
Cell Commun Signal 23, 472 (2025). DOI: 10.1186/s12964-025-02460-0
Shukla, S., Kadam, A., Goyani, S. et al. (2025) -
Cognitive function correlates with gastric alpha-synuclein seeding activity in early Parkinson’s disease
NPJ Parkinsons Dis. 11, 311 (2025). DOI: 10.1038/s41531-025-01152-3
Shin, C., Im, J., Han, J. et al. (2025) -
The involvement of microglia and the CXCL16-CXCR6 axis in the recruitment of CD8+ T cells to an amyloidogenic mouse brain
Sci Rep 15, 38221 (2025). DOI: 10.1038/s41598-025-22137-5
Zattoni, M., Bernegger, S., Weinbender, S. et al. (2025) -
Seeding Alzheimer’s disease-associated tau pathology in MAPT knock-in primary neurons causes early axonopathy and synaptic dysfunction
Sci Rep 15, 38140 (2025). DOI: 10.1038/s41598-025-21920-8
Mueller, R., Combs, B., Kanaan, N. et al. (2025) -
Lamotrigine Restores Impairments in Theta Rhythms and LTP as Early Biomarkers of Aβ1-42-Induced Hippocampal Network Dysfunction
Aging and disease (2025) DOI: 10.14336/AD.2025.0796
Studzian, M., Bobula, B., MacIver, M. et al. (2025) -
PET-MRI biomarkers reveal efficacy of a novel NLRP3 2 inhibitor in Parkinson’s disease models
Oxford Academic, Brain, (2025). DOI: 10.1093/brain/awaf372
Albornoz, E., Mardon, K., Bhalla, R. et al. (2025) -
Chronic Sleep Fragmentation Differentially Affects Alzheimer’s Disease Pathology in Male and Female APPSAA Knock-in Mice
J Inflamm Res. 2025;18:14325-14341. DOI: 10.2147/JIR.S544625
Hawkins, M., Whitlock, H., Johnson, C et al. (2025) -
Peptide Sequencing With Single Acid Resolution Using a Sub-Nanometer Diameter Pore
Advanced Functional Materials (2025). DOI: 10.1002/adfm.202515800
Paul, A., Rayabharam, A., Almonte, L. et al. (2025) -
Synthetic chaperone based on Hsp90-Tau interaction inhibits Tau aggregation and rescues physiological Tau-Microtubule interaction
Nat Commun 16, 8756 (2025). DOI: 10.1038/s41467-025-63824-1
Di Lorenzo, D., Bisi, N., Kaffy, J. et al. (2025) -
Incubation with tau aggregates increases hippocampal circuit excitability and enhances long-term depression in acute mouse hippocampal slices
Front. Neural Circuits. (2025) 19:1596989. doi: 10.3389/fncir.2025.1596989
Wang A., Richardson A., Emmett I. et al. (2025)