Publications
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Facile single-molecule pull-down assay for analysis of endogenous proteins
Physical Biology; doi: 10.1088/1478-3975/ab0792..
Benjamin Croop, Kyu Young Han (2019) -
Influence of Matrix Metallopeptidase 9 on Beta-Amyloid Elimination Across the Blood-Brain Barrier.
Mol Neurobiol.; DOI: 10.1007/s12035-019-01672-z.
Ben Shackleton, Charis Ringland, Laila Abdullah, Michael Mullan, Fiona Crawford , Corbin Bachmeier (2019) -
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes
Nature Communications; https://doi.org/10.1038/s41467-018-07699-5.
Ryan Limbocker, Sean Chia, Francesco S. Ruggeri, Michele Perni,...Christopher M. Dobson (2019) -
In vitro studies of the neuroprotective activities of astaxanthin and fucoxanthin against amyloid beta (Aβ1-42) toxicity and aggregation
Neurochemistry International; https://doi.org/10.1016/j.neuint.2019.01.010.
Mousa Alghazwi, ScottSmid, Ian Musgrave, Wei Zhang (2019) -
Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice
Molecular and Cellular Neuroscience; https://doi.org/10.1016/j.mcn.2019.103390.
Chaitanya Chakravarthi Gali, Elham Fanaee-Danesh, Martina Zandl-Lang (2019) -
Marine bacterial extracts as a new rich source of drugs against Alzheimer’s disease.
Journal of Neurochemistry; https://doi.org/10.1111/jnc.14847.
Beika Zhu, Zhongrui Li, Pei‐Yuan Qian, Karl Herrup (2019) -
Small molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease
bioRxiv; doi: https://doi.org/10.1101/729392.
Gabriella T. Heller, Francesco A. Aprile, Thomas C. T. Michaels, Ryan Limbocker, Michele Perni, Francesco Simone Ruggeri, Benedetta Mannini, Thomas Löhr, Massimiliano Bonomi, Alfonso De Simone, Isabella C. Felli, Roberta Pierattelli, Tuomas P. J. Knowles, Christopher M. Dobson, Michele Vendruscolo (2019) -
17 Oxo Sparteine and Lupanine, Obtained from Cytisus scoparius, Exert a Neuroprotection against Soluble Oligomers of Amyloid-β Toxicity by Nicotinic Acetylcholine Receptors.
Journal of Alzheimer’s Disease; DOI: 10.3233/JAD-180945.
Gavilan, J., Mennickent, D., Ramirez-Molina, O. et al. (2019) -
Resveratrol alleviates motor and cognitive deficits and neuropathology in the A53T α-synuclein mouse model of Parkinson's disease.
Food & Function; DOI: 10.1039/c8fo00964c.
Li-fan Zhang, Xiao-lin Yu, Mei Ji, Shu-ying Liu, Xiao-ling Wu, Yu-jiong Wang, Rui-tian Liu (2018) -
α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome.
Spandidos Publications; https://doi.org/10.3892/etm.2019.8297.
Wang,X., Chi,J., Huang,D., Ding,L., Zhao,X., Jiang,L., Yu,Y., Gao,F. (2018) -
Effects of single and combined immunotherapy approach targeting amyloid β protein and α-synuclein in a dementia with Lewy bodies-like model..
Alzheimers Dement.; doi: 10.1016/j.jalz.2019.02.002.
Markus Mandler, Edward Rockenstein, Cassia Overk, Michael Mante, Jazmin Florio, Anthony Adame, Changyoun Kim, Radmila Santic, Achim Schneeberger, Frank Mattner, Sabine Schmidhuber, Gergan Galabova, Brian Spencer, Eliezer Masliah, Robert A.Rissman (2018) -
TREM2 deficiency aggravates α-synuclein–induced neurodegeneration and neuroinflammation in Parkinson’s disease models..
FASEB J.; DOI: 10.1096/fj.201900992R.
Ying Guo, Xinbing Wei, Hua Yan, Yue Qin, Shaoqi Yan, Jia Liu, Yong Zhao, Fan Jiang, and Haiyan Lou (2018) -
Functionalization of the TMEM175 p.M393T Variant as a risk factor for Parkinson Disease..
Hum Mol Genet.; DOI: 10.1093/hmg/ddz136.
Sarah Jinn, Cornelis Blauwendraat, Dawn Toolan, Cheryl A Gretzula, Robert E Drolet, Sean Smith, Mike A Nalls, Jacob Marcus, Andrew B Singleton, David J Stone (2018) -
Increased Immune Activation by Pathologic α‐Synuclein in Parkinson's Disease.
Annals of Neurology; https://doi.org/10.1002/ana.25557.
Veselin Grozdanov, Luc Bousset, Meike Hoffmeister, Corinna Bliederhaeuser, Christoph Meier, Karine Madiona, Laura Pieri, Martin Kiechle, Pamela J. McLean, Jan Kassubek, Christian Behrends, Albert C Ludolph, Jochen H Weishaupt, Ronald Melki, Karin M Danzer (2018) -
Effect of naturally occurring α-synuclein-antibodies on toxic α-synuclein-fragments.
Neuroscience Letters; https://doi.org/10.1016/j.neulet.2019.04.004.
Monika Rabenstein Daniela Besong Agbo, Elias Wolfah, Judith Dams, Marina Nicolai, Andreas Roeder, Michael Bacher, Richard C. Dodel, Carmen Noelker (2018) -
Reduction of Immunoreactivity Against the C-Terminal Region of the Intracellular α-Synuclein by Exogenous α-Synuclein Aggregates: Possibility of Conformational Changes..
Journal of Parkinson’s Disease; doi: 10.3233/JPD-160835..
Izumi Yasuhiko, Kondo, Naoto, Takahashi Ryosuke, Akaike Akinori, Kume Toshiaki (2018) -
Identification of a New α-Synuclein Aggregation Inhibitor via Mass Spectrometry Based Screening.
ACS Chem. Neurosci.; https://doi.org/10.1021/acschemneuro.9b00092.
Mingming Xu, Wendy Loa-Kum-Cheung, Haiyan Zhang, Ronald J. Quinn, George D. Mellick (2018) -
Interferon-γ Potentiates α-Synuclein-induced Neurotoxicity Linked to Toll-like Receptors 2 and 3 and Tumor Necrosis Factor-α in Murine Astrocytes..
Mol Neurobiol.; DOI: 10.1007/s12035-019-1567-5.
Jintang Wang, Zheng Chen, Jeremy D. Walston, Peisong Gao, Maolong Gao, Sean X. Leng (2018) -
Characterization of pathology-inducing α-synuclein species from human diseased brain tissue.
bioRxiv; doi: https://doi.org/10.1101/588335.
John D. Graef, Nina Hoque, Craig Polson, Ling Yang, Lawrence Iben, Yang Cao, Nino Devidze, Michael K. Ahlijanian, Jere E. Meredith Jr. (2018) -
Electrochemical Detection of Interaction between Copper(II) and Peptides Related to Pathological α-Synuclein Mutants.
Anal Chem.; DOI: 10.1021/acs.analchem.8b03612.
ShaoPei Li, Kagan Kerman (2018)
