Welcome to rPeptide

We provide high quality Peptide, Reagents, Proteins, Antibodies,
and more, with a focus on Alzheimer’s and Parkinson’s disease research.
Our proprietary platform vector technology enables the recombinant expression
of historically difficult peptides/ proteins as soluble peptides/ proteins in E. coli.
We offer a large selection of Beta Amyloids, Taus, Synucleins, Calmodulins, Custom Products and more.

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rPeptide Citations

December 2014 — Wiley Online Library: Alterations in brain leptin signalling in spite of unchanged CSF leptin levels in Alzheimer's disease | Beta Amyloid Products

November 2014 — ACS Publications: A Synchrotron-based Hydroxyl Radical Footprinting Analysis of Amyloid Fibrils and Pre-fibrillar Intermediates with Residue-specific Resolution | Beta Amyloid Products

November 2014 — Springer Link: β-Amyloid peptides display protective activity against the human Alzheimer’s disease-associated herpes simplex virus-1 | Beta Amyloid Products

November 2014 — Science Direct: Increased plasma oligomeric alpha-synuclein in patients with lysosomal storage diseases | Synuclein Products

November 2014 — ACS Publications: Capping of Aβ42 oligomers by small molecule inhibitors | Beta Amyloid Products

October 2014 — The Journal of Biological Chemistry: The Spleen Tyrosine Kinase (syk) Regulates Alzheimer's Aβ Production and Tau Hyperphosphorylation | Beta Amyloid Products

October 2014 — The Journal of Biological Chemistry: The Spleen Tyrosine Kinase (syk) Regulates Alzheimer's Aβ Production and Tau Hyperphosphorylation | Tau Products

October 2014 — Annals of Neurology: Amyloid-β efflux from the central nervous system into the plasma | Beta Amyloid Products

October 2014 — Nature: A Smoothened receptor agonist is neuroprotective and promotes regeneration after ischemic brain injury | Other Products

October 2014 — Science Direct: In vitro discrimination of the role of LRP1 at the BBB cellular level: Focus on brain capillary endothelial cells and brain pericytes | Beta Amyloid Products

September 2014 — Science Direct: A 170 kDa multi-domain cystatin of Fasciola gigantica is active in the male reproductive system | Other Products

September 2014 — The Journal of Biological Chemistry: Molecular Mechanisms of Alzheimer′s Disease Protection by the A673T Allele of Amyloid Precursor Protein | Beta Amyloid Products

September 2014 — FPO: Compounds and Compositions for use a Modulators of Tau Aggregation and Alleviation of Tauopathies | Tau Products

August 2014 — Wiley Online Library: Fibrillar β-Amyloid 1-42 Alters Cytokine Secretion, Cholinergic Signalling and Neuronal Differentiation | Beta Amyloid Products

August 2014 — Science Direct: Specific binding of intravenous immunoglobulin products to tau peptide fragments | Tau Products

August 2014 — FPO: Protein Damage in Aging and Age-Related Diseases | Synuclein Products

August 2014 — The Journal of Biological Chemistry: Aβ-specific DARPins as a novel class of potential therapeutics for Alzheimer’s disease | Beta Amyloid Products

July 2014 — Science Direct: Nanoliposomes presenting on surface a cis-glycofused benzopyran compound display binding affinity and aggregation inhibition ability towards Amyloid β1-42 peptide | Beta Amyloid Products

July 2014 — Scientific Reports: Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry | Synuclein Products

July 2014 — ACS Publications: ESEEM Analysis of Multi-Histidine Cu(II)-Coordination in Model Complexes, Peptides, and Amyloid-β | Beta Amyloid Products

July 2014 — The Journal of Neuroscience: Transgenic Mice Overexpressing Amyloid Precursor Protein Exhibit Early Metabolic Deficits and a Pathologically Low Leptin State Associated with Hypothalamic Dys | Beta Amyloid Products

July 2014 — Wiley Online Library: Intracellular selection of peptide inhibitors that target disulphide-bridged Aβ42 oligomers | Beta Amyloid Products

July 2014 — NIH.gov: Characterizing Methyl-Bearing Side Chain Contacts and Dynamics Mediating Amyloid-b Protofibril Interactions Using 13C methyl-DEST and Lifetime Line Broadening | Beta Amyloid Products

July 2014 — Science Direct: The use of nanopore analysis for discovering drugs which bind to α-synuclein for treatment of Parkinson's disease | Synuclein Products

July 2014 — Wiley Online Library: A distinct subfraction of Aβ is responsible for the high-affinity Pittsburgh compound B-binding site in Alzheimer's disease brain | Beta Amyloid Products

June 2014 — ACS Publications: Multifunctional D2/D3 Agonist D-520 with High in Vivo Efficacy: Modulator of Toxicity of Alpha-Synuclein Aggregates | Synuclein Products

June 2014 — Science Direct: The amyloid-β degradation pattern in plasma—A possible tool for clinical trials in Alzheimer's disease | Beta Amyloid Products

June 2014 — Science Direct: A novel cell line from spontaneously immortalized murine microglia | Beta Amyloid Products

June 2014 — Metapress: Modulation of Amyloid-β Protein Precursor Expression by HspB1 | Beta Amyloid Products

May 2014 — Oxford Journals: Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain | Beta Amyloid Products

May 2014 — Universitat de Marburg Library: Annonacin, ein natürlicher Komplex-I Inhibitor, erhöht die Tau-Phosphorylierung im Gehirn von FTDP-17 transgenen Mäusen | Tau Products

May 2014 — JCI: The Journal of Clinical Investigation: Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation | Synuclein Products

May 2014 — The Journal of Physical Chemistry: Pyroglutamylated Amyloid-β Peptide Reverses Cross β-Sheets by a Prion-Like Mechanism | Beta Amyloid Products

May 2014 — pfizerpro.com: Activity of Pramlintide, Rat and Human Amylin but not ABeta 1–42 at Human Amylin Receptors | Beta Amyloid Products

May 2014 — Karolinska Institutet: Regenerating the Brain: Stem Cell Differentiation and Cholinergic Dysfunction in Alzheimer Disease | Beta Amyloid Products

May 2014 — Science Direct: Specific binding of intravenous immunoglobulin products to tau peptide fragments | Tau Products

May 2014 — Science Direct: The phosphorylation of Hsp20 enhances its association with amyloid-β to increase protection against neuronal cell death | Beta Amyloid Products

May 2014 — Springer Link: Qualification and application of a liquid chromatography–tandem mass spectrometric method for the determination of human Aβ1-40 and Aβ1-42 peptides in transgenic mouse plasma using micro-elution solid phase extraction | Beta Amyloid Products

April 2014 — Science Direct: Testing synthetic amyloid-β aggregation inhibitor using single molecule atomic force spectroscopy | Beta Amyloid Products

April 2014 — PLOS One: Extracellular α-Synuclein Leads to Microtubule Destabilization via GSK-3β-Dependent Tau Phosphorylation in PC12 Cells | Synuclein Products

April 2014 — FEBS Journal: Resistance of naturally secreted -synuclein to proteolysis | Synuclein Products

April 2014 — The Journal of Neuroscience: Suppression of Alzheimer-Associated Inflammation by Microglial Prostaglandin-E2 EP4 Receptor Signaling | Beta Amyloid Products

April 2014 — FEBS Journal: Cu(II) and dopamine bind to α-Synuclein and cause large conformational changes | Synuclein Products

April 2014 — Science Direct: Polyfluorinated bis-styrylbenzenes as amyloid-β plaque binding ligands | Beta Amyloid Products

April 2014 — Clinical Chemistry: Quantification of Tau in Cerebrospinal Fluid by Immunoaffinity Enrichment and Tandem Mass Spectrometry | Beta Amyloid Products

March 2014 — PLOS One: Modulation of RNase E Activity by Alternative RNA Binding Sites | Other Products

March 2014 — PLOS One: Extracellular Proteolysis of Apolipoprotein E (apoE) by Secreted Serine Neuronal Protease | Beta Amyloid Products

March 2014 — The Journal of Biological Chemistry: β-Amyloid Fibrils in Alzheimer Disease Are Not Inert When Bound to Copper Ions but Can Degrade Hydrogen Peroxide and Generate Reactive Oxygen Species | Beta Amyloid Products

March 2014 — IOS Press: Synergistic Inhibition of Synaptic Signaling in Cortical Cultures by Subcytotoxic Levels of Oligomerized Amyloid-β and Iron: Alleviation by Zinc | Beta Amyloid Products

March 2014 — Metapress: Methylglyoxal Produced by Amyloid-β Peptide-Induced Nitrotyrosination of Triosephosphate Isomerase Triggers Neuronal Death in Alzheimer's Disease | Beta Amyloid Products

March 2014 — ACS Publications: Retro-inversal of Intracellular Selected β-Amyloid-Interacting Peptides: Implications for a Novel Alzheimer’s Disease Treatment | Beta Amyloid Products

March 2014 — IOS Press: Adenosine Triphosphate (ATP) Reduces Amyloid-β Protein Misfolding in vitro | Beta Amyloid Products

March 2014 — Science Direct: A glucan isolated from flowers of Lonicera japonica Thunb. inhibits aggregation and neurotoxicity of Aβ | Beta Amyloid Products

March 2014 — Science Direct: Pituitary adenylate cyclase-activating polypeptide protects against β-amyloid toxicity | Beta Amyloid Products

March 2014 — Biopolymers: Improved chemical synthesis of hydrophobic Aβ peptides using addition of C-terminal lysines later removed by carboxypeptidase B | Beta Amyloid Products

March 2014 — Brain Pathology: Reduced Vascular Endothelial Growth Factor and Capillary Density in the Occipital Cortex in Dementia with Lewy Bodies | Beta Amyloid Products

February 2014 — ACS Publications: Predicting the Reactivity of Nitrile-Carrying Compounds with Cysteine: A Combined Computational and Experimental Study | Other Products

February 2014 — Scientific Reports: Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation | Beta Amyloid Products

February 2014 — DOI 10.1007/s00401-014-1256-4: Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials | Synuclein Products

February 2014 — DOI: 10.1111/bpa.12130: Reduced vascular endothelial growth factor and capillary density in the occipital cortex in dementia with Lewy bodies | Synuclein Products

February 2014 — The Journal of Biological Chemistry: Molecular Basis for Preventing α-Synuclein Aggregation by a Molecular Tweezer | Synuclein Products

February 2014 — Clinical Chemistry: Quantification of Tau in Cerebrospinal Fluid by Immunoaffinity Enrichment and Tandem Mass Spectrometry | Tau Products

February 2014 — PLOS One: Comparable Autoantibody Serum Levels against Amyloid- and Inflammation-Associated Proteins in Parkinson’s Disease Patients and Controls | Beta Amyloid Products

February 2014 — PLoS ONE: Comparable Autoantibody Serum Levels against Amyloid- and Inflammation-Associated Proteins in Parkinson’s Disease Patients and Controls | Synuclein Products

January 2014 — Diva-Portal: Interaction studies of luminescent conjugated oligothiophenes with aggregated Amyloid β | Beta Amyloid Products

January 2014 — Invest. Ophthalmol. Vis. Sci.: Development of allele specific gene silencing siRNAs for TGFBI Arg124Cys in Lattice Corneal Dystrophy Type I | Beta Amyloid Products

January 2014 — Cambridge University Press: Novel 5-aryloxypyrimidine SEN1576 as a candidate for the treatment of Alzheimer's disease | Beta Amyloid Products

January 2014 — Nature.com: Zinc depletion regulates the processing and secretion of IL-1β | Beta Amyloid Products

January 2014 — ACS Publications: Bexarotene Blocks Calcium-Permeable Ion Channels Formed by Neurotoxic Alzheimer’s β-Amyloid Peptides | Beta Amyloid Products

January 2014 — Mol. Pharmaceutics, Just Accepted Manuscript DOI: 10.1021/mp400230s Publication Date (Web): January 31, 2014 Copyright © 2014 American Chemical Society: Towards a rationale for the PTC124 (Ataluren) promoted readthrough of premature stop codons: a computational approach and GFP-reporter cell-based assay. | Other Products

January 2014 — Submission date 24 April 2013 Acceptance date 14 January 2014 Publication date 21 January 2014: Kinome and mRNA expression profiling of high-grade osteosarcoma cell lines implies Akt signaling as possible target for therapy | Other Products

January 2014 — Science Direct: Structural characterization of the minimal segment of TDP-43 competent for aggregation | Other Products

January 2014 — Copyright © 2014 Elsevier B.V. except certain content provided by third parties. ScienceDirect® is a registered trademark of Elsevier B.V.: “Structural characterization of the minimal segment of TDP-43 competent for aggregation” | Other Products

January 2014 — Informa Healthcare: Peptide nucleic acids: a review on recent patents and technology transfer | Other Products

January 2014 — 1Laboratory of Morphogenesis, Center of Advanced Study in Botany, Banaras Hindu University, Varanasi-221005, India 2Molecular Biology Section, Laboratory of Algal Biology, Center of Advanced Study in Botany, Banaras Hindu University, Varanasi-221005, India.: Enhanced photosynthesis and Carbon metabolism favor Arsenic tolerance in Artemisia annua, a medicinal plant as revealed by homology-based Proteomics | Other Products