Publications
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Is Formaldehyde the Missing Link in AD Pathology? The Differential Aggregation of Amyloid-Beta with APOE Isoforms In Vitro.
Curr Alzheimer Res.; DOI:10.2174/1567205011666140425112043.
Rizak, J.D.; Ma, Y; Hu, X (2014) -
Methylglyoxal Produced by Amyloid-β Peptide-Induced Nitrotyrosination of Triosephosphate Isomerase Triggers Neuronal Death in Alzheimer's Disease
Journal of Alzheimer’s Disease; DOI 10.3233/JAD-131685.
Tajes M, Eraso-Pichot A, Rubio-Moscardó F, et al (2014) -
Capping of Aβ42 Oligomers by Small Molecule Inhibitors
Biochemistry; DOI: 10.1021/bi500910b.
Fu, Aucoin, Ahmed et al (2014) -
Retro-inversal of Intracellular Selected β-Amyloid-Interacting Peptides: Implications for a Novel Alzheimer’s Disease Treatment
Biochemistry; DOI: 10.1021/bi5001257.
Acerra N, Kad N M, Griffith D A et al (2014) -
Suppression of Alzheimer-Associated Inflammation by Microglial Prostaglandin-E2 EP4 Receptor Signaling
The Journal of Neuroscience; doi: 10.1523/JNEUROSCI.0410-14.2014.
Nathaniel S. Woodling, Qian Wang, Prachi G. Priyam, Paul Larkin, Ju Shi, Jenny U. Johansson, Irene Zagol-Ikapitte, Olivier Boutaud, and Katrin I. Andreasson (2014) -
The Spleen Tyrosine Kinase (syk) Regulates Alzheimer's Aβ Production and Tau Hyperphosphorylation
The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.608091.
Paris D, Ait-Ghezala G, Bachmeier C, et al (2014) -
Accumulation of α-synuclein in dementia with Lewy bodies is associated with decline in the α-synuclein-degrading enzymes kallikrein-6 and calpain-1
Acta Neuropathol Commun.; doi: 10.1186/s40478-014-0164-0
Scott Miners, Ruth Renfrew, Marta Swirski, Seth Love (2013) -
Naturally Occurring Alpha-Synuclein Autoantibodies in Parkinson’s Disease: Sources of (Error) Variance in Biomarker Assays
PLoS One; https://doi.org/10.1371/journal.pone.0114566.
Heinzel S, Gold M, Deuschle C et al (2013) -
Increased plasma oligomeric alpha-synuclein in patients with lysosomal storage diseases
Neuroscience Letters; doi:10.1016/j.neulet.2014.09.041.
Pchelina, S.N., Nuzhnyib E.P., Emelyanov A.K., et al (2013) -
Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson’s disease
Acta Neurolpathol.; doi: 10.1007/s00401-014-1314-y.
Shi, Min et al (2013) -
Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry
Scientific Reports; doi:10.1038/srep05797
Kellie, J., Higgs, R., Ryder, J. et al (2013) -
The use of nanopore analysis for discovering drugs which bind to α-synuclein for treatment of Parkinson's disease
European Journal of Medicinal Chemistry; DOI: 10.1016/j.ejmech.2014.07.090.
Tavassoly O, Kakish J, Nokhrin S , et al (2013) -
Multifunctional D2/D3 Agonist D-520 with High in Vivo Efficacy: Modulator of Toxicity of Alpha-Synuclein Aggregates
ACS Chemical Neuroscience; DOI: 10.1021/cn500084x.
Modi G, Voshavar C, Gogoi S et al (2013) -
Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation
JCI: The Journal of Clinical Investigation; doi:10.1172/JCI72176..
Liu G, Yu J, Ding J et al (2013) -
Cu(II) and dopamine bind to α-Synuclein and cause large conformational changes
FEBS Journal; DOI: 10.1111/febs.12817
Tavassoly O, Nokhrin S, Dmitriev O Y et al (2013) -
Extracellular α-Synuclein Leads to Microtubule Destabilization via GSK-3β-Dependent Tau Phosphorylation in PC12 Cells.
PLOS One; DOI: 10.1371/journal.pone.0094259.
Gąssowska M, Czapski G A, Pająk B, et al (2013) -
Resistance of naturally secreted α-synuclein to proteolysis
FASEB Journal; doi: 10.1096/fj.13-245852.
Ximerakis M, Pampalakis G, Roumeliotis T I et al (2013) -
Comparable Autoantibody Serum Levels against Amyloid- and Inflammation-Associated Proteins in Parkinson’s Disease Patients and Controls
PLoS ONE; DOI: 10.1371/journal.pone.0088604.
Maetzler W, Apel A, Langkamp M et al (2013) -
Molecular Basis for Preventing α-Synuclein Aggregation by a Molecular Tweezer
The Journal of Biological Chemistry; doi: 10.1074/jbc.M113.524520.
Acharya, Srabasti et al (2013) -
Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials
Acta Neuropathol 127, 861–879 (2014). https://doi.org/10.1007/s00401-014-1256-4
Mandler, M., Valera, E., Rockenstein, E. et al. (2013)
