Publications
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Accumulation of α-synuclein in dementia with Lewy bodies is associated with decline in the α-synuclein-degrading enzymes kallikrein-6 and calpain-1
Acta Neuropathol Commun.; doi: 10.1186/s40478-014-0164-0
Scott Miners, Ruth Renfrew, Marta Swirski, Seth Love (2013) -
Naturally Occurring Alpha-Synuclein Autoantibodies in Parkinson’s Disease: Sources of (Error) Variance in Biomarker Assays
PLoS One; https://doi.org/10.1371/journal.pone.0114566.
Heinzel S, Gold M, Deuschle C et al (2013) -
Increased plasma oligomeric alpha-synuclein in patients with lysosomal storage diseases
Neuroscience Letters; doi:10.1016/j.neulet.2014.09.041.
Pchelina, S.N., Nuzhnyib E.P., Emelyanov A.K., et al (2013) -
Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson’s disease
Acta Neurolpathol.; doi: 10.1007/s00401-014-1314-y.
Shi, Min et al (2013) -
Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry
Scientific Reports; doi:10.1038/srep05797
Kellie, J., Higgs, R., Ryder, J. et al (2013) -
The use of nanopore analysis for discovering drugs which bind to α-synuclein for treatment of Parkinson's disease
European Journal of Medicinal Chemistry; DOI: 10.1016/j.ejmech.2014.07.090.
Tavassoly O, Kakish J, Nokhrin S , et al (2013) -
Multifunctional D2/D3 Agonist D-520 with High in Vivo Efficacy: Modulator of Toxicity of Alpha-Synuclein Aggregates
ACS Chemical Neuroscience; DOI: 10.1021/cn500084x.
Modi G, Voshavar C, Gogoi S et al (2013) -
Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation
JCI: The Journal of Clinical Investigation; doi:10.1172/JCI72176..
Liu G, Yu J, Ding J et al (2013) -
Cu(II) and dopamine bind to α-Synuclein and cause large conformational changes
FEBS Journal; DOI: 10.1111/febs.12817
Tavassoly O, Nokhrin S, Dmitriev O Y et al (2013) -
Extracellular α-Synuclein Leads to Microtubule Destabilization via GSK-3β-Dependent Tau Phosphorylation in PC12 Cells.
PLOS One; DOI: 10.1371/journal.pone.0094259.
Gąssowska M, Czapski G A, Pająk B, et al (2013) -
Resistance of naturally secreted α-synuclein to proteolysis
FASEB Journal; doi: 10.1096/fj.13-245852.
Ximerakis M, Pampalakis G, Roumeliotis T I et al (2013) -
Comparable Autoantibody Serum Levels against Amyloid- and Inflammation-Associated Proteins in Parkinson’s Disease Patients and Controls
PLoS ONE; DOI: 10.1371/journal.pone.0088604.
Maetzler W, Apel A, Langkamp M et al (2013) -
Molecular Basis for Preventing α-Synuclein Aggregation by a Molecular Tweezer
The Journal of Biological Chemistry; doi: 10.1074/jbc.M113.524520.
Acharya, Srabasti et al (2013) -
Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials
Acta Neuropathol 127, 861–879 (2014). https://doi.org/10.1007/s00401-014-1256-4
Mandler, M., Valera, E., Rockenstein, E. et al. (2013) -
Reduced vascular endothelial growth factor and capillary density in the occipital cortex in dementia with Lewy bodies
Brain Pathology, 24: 334-343. https://doi.org/10.1111/bpa.12130
Miners, S., Moulding, H., de Silva, R. and Love, S. (2013) -
Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent
Neurobiology of Aging; DOI: http://dx.doi.org/10.1016/j.neurobiolaging.2014.12.004.
Miranda E. Orr, Valentina R. Garbarino, Angelica Salinas, Rochelle Buffenstein (2013) -
Tau Monoclonal Antibody Generation based on Humanized Yeast Models: Impact on Tau Oligomerization and Diagnostics.
The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.627919.
Rosseels J, Van den Brande J, Violet M et al (2013) -
The Spleen Tyrosine Kinase (syk) Regulates Alzheimer's Aβ Production and Tau Hyperphosphorylation
The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.608091.
Paris D, Ait-Ghezala G, Bachmeier C et al (2013) -
Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice
Front Aging Neurosci.; doi: 10.3389/fnagi.2014.00214.
Sontag J-M, Wasek B, Taleski G et al (2013) -
Specific binding of intravenous immunoglobulin products to tau peptide fragments.
Science Direct; http://dx.doi.org/10.1016/j.intimp.2014.05.009.
Smith L M, Coffey M P, Loeffler D A (2013)
