Publications
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Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events
Neurobiol Dis.; doi: 10.1016/j.nbd.2013.10.007
Bhaskar, Kiran et al (2014) -
Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease.
PLoS One; doi: 10.1371/journal.pone.0101643v.
Katherine R. Sadleir, William A. Eimer, Randal J. Kaufman, Pavel Osten, Robert Vassar (2014) -
Novel 5-aryloxypyrimidine SEN1576 as a candidate for the treatment of Alzheimer's disease
International Journal of Neuropsychopharmacology; DOI: http://dx.doi.org/10.1017/S1461145713000886.
O'Hare, Scopes, Kim et al (2014) -
Reciprocal modulation of Aβ42 aggregation by copper and homocysteine.
Front Aging Neurosci.; https://doi.org/10.3389/fnagi.2014.00237.
Keskitalo, Farkas, Hanenberg et al (2014) -
Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microglia in vitro
GLIA; DOI: 10.1002/glia.22619.
Mulder, Nielsen, Blankenstein et al (2014) -
Zinc depletion regulates the processing and secretion of IL-1β
Cell Death & Disease; doi:10.1038/cddis.2013.547.
Summersgill H, England H, Lopez-Castejon G, et al (2014) -
Aβ-specific DARPins as a novel class of potential therapeutics for Alzheimer’s disease
The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.564013.
Nitsch Maier, Andreas Plückthun and Roger M. Claudia Späni, Rebecca Derungs, Marcel Parizek, Lisa Strobel, Susann Cattepoel, Kulic, Tobias Welt, Fabian Wirth, Petra Michael Hanenberg, Jordan McAfoose, Luka (2014) -
A novel cell line from spontaneously immortalized murine microglia
Journal of Neuroscience Methods; DOI: 10.1016/j.jneumeth.2014.05.021.
Kumi Nagamoto-Combsa, Joshua Kulasb, Colin K. Combs (2014) -
Testing synthetic amyloid-β aggregation inhibitor using single molecule atomic force spectroscopy
Biosensors and Bioelectronics; http://dx.doi.org/10.1016/j.bios.2013.10.060.
Francis T. Hanea, Brenda Y. Leea, Anahit Petoyanb, Arvi Raukb, Zoya Leonenko (2014) -
Is Formaldehyde the Missing Link in AD Pathology? The Differential Aggregation of Amyloid-Beta with APOE Isoforms In Vitro.
Curr Alzheimer Res.; DOI:10.2174/1567205011666140425112043.
Rizak, J.D.; Ma, Y; Hu, X (2014) -
Methylglyoxal Produced by Amyloid-β Peptide-Induced Nitrotyrosination of Triosephosphate Isomerase Triggers Neuronal Death in Alzheimer's Disease
Journal of Alzheimer’s Disease; DOI 10.3233/JAD-131685.
Tajes M, Eraso-Pichot A, Rubio-Moscardó F, et al (2014) -
Capping of Aβ42 Oligomers by Small Molecule Inhibitors
Biochemistry; DOI: 10.1021/bi500910b.
Fu, Aucoin, Ahmed et al (2014) -
Retro-inversal of Intracellular Selected β-Amyloid-Interacting Peptides: Implications for a Novel Alzheimer’s Disease Treatment
Biochemistry; DOI: 10.1021/bi5001257.
Acerra N, Kad N M, Griffith D A et al (2014) -
Suppression of Alzheimer-Associated Inflammation by Microglial Prostaglandin-E2 EP4 Receptor Signaling
The Journal of Neuroscience; doi: 10.1523/JNEUROSCI.0410-14.2014.
Nathaniel S. Woodling, Qian Wang, Prachi G. Priyam, Paul Larkin, Ju Shi, Jenny U. Johansson, Irene Zagol-Ikapitte, Olivier Boutaud, and Katrin I. Andreasson (2014) -
The Spleen Tyrosine Kinase (syk) Regulates Alzheimer's Aβ Production and Tau Hyperphosphorylation
The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.608091.
Paris D, Ait-Ghezala G, Bachmeier C, et al (2014) -
Accumulation of α-synuclein in dementia with Lewy bodies is associated with decline in the α-synuclein-degrading enzymes kallikrein-6 and calpain-1
Acta Neuropathol Commun.; doi: 10.1186/s40478-014-0164-0
Scott Miners, Ruth Renfrew, Marta Swirski, Seth Love (2013) -
Naturally Occurring Alpha-Synuclein Autoantibodies in Parkinson’s Disease: Sources of (Error) Variance in Biomarker Assays
PLoS One; https://doi.org/10.1371/journal.pone.0114566.
Heinzel S, Gold M, Deuschle C et al (2013) -
Increased plasma oligomeric alpha-synuclein in patients with lysosomal storage diseases
Neuroscience Letters; doi:10.1016/j.neulet.2014.09.041.
Pchelina, S.N., Nuzhnyib E.P., Emelyanov A.K., et al (2013) -
Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson’s disease
Acta Neurolpathol.; doi: 10.1007/s00401-014-1314-y.
Shi, Min et al (2013) -
Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry
Scientific Reports; doi:10.1038/srep05797
Kellie, J., Higgs, R., Ryder, J. et al (2013)
