Publications
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Alterations in brain leptin signalling in spite of unchanged CSF leptin levels in Alzheimer's disease
Aging Cell; DOI: 10.1111/acel.12281.
Maioli, Lodeiro, Merino-Serrais et al (2014) -
Identification and Preclinical Pharmacology of the -Secretase Modulator BMS-869780
International Journal of Alzheimer’s Disease; http://dx.doi.org/10.1155/2014/431858
Toyn, Thompson, Lentz et al (2014) -
A Synchrotron-based Hydroxyl Radical Footprinting Analysis of Amyloid Fibrils and Pre-fibrillar Intermediates with Residue-specific Resolution
ACS Publications; DOI: 10.1021/bi5010409.
Klinger, Kiselar, Ilchenko et al (2014) -
Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation
Scientific Reports; doi:10.1038/srep04004.
Tinker-Mill, Mayes, Allsop et al (2014) -
In vitro discrimination of the role of LRP1 at the BBB cellular level: Focus on brain capillary endothelial cells and brain pericytes
Brain Research; doi:10.1016/j.brainres.2014.10.047.
Candela, Saint-Pola, Boucau et al (2014) -
β-Amyloid Fibrils in Alzheimer Disease Are Not Inert When Bound to Copper Ions but Can Degrade Hydrogen Peroxide and Generate Reactive Oxygen Species
The Journal of Biological Chemistry; 10.1074/jbc.M113.525212.
Mayes,Tinker-Mill, Kolosov et al (2014) -
Resting microglia react to Aβ42 fibrils but do not detect oligomers or oligomer-induced neuronal damage.
Neurobiol Aging.; doi: 10.1016/j.neurobiolaging.2014.05.023.
Denise Ferrera, Nadia Mazzaro, Claudio Canale, Laura Gasparini (2014) -
Transgenic Mice Overexpressing Amyloid Precursor Protein Exhibit Early Metabolic Deficits and a Pathologically Low Leptin State Associated with Hypothalamic Dysfunction in Arcuate Neuropeptide Y Neurons
The Journal of Neuroscience; 10.1523/JNEUROSCI.0872-14.2014.
Ishii, Wang, Racchumi et al (2014) -
The amyloid-β degradation pattern in plasma—A possible tool for clinical trials in Alzheimer's disease
Neuroscience Letters; 10.1016/j.neulet.2014.04.041
Pannee, Törnqvist, Westerlund et al (2014) -
Development of Allele-Specific Gene-Silencing siRNAs for TGFBI Arg124Cys in Lattice Corneal Dystrophy Type I
Invest. Ophthalmol. Vis. Sci.; doi: 10.1167/iovs.13-13279.
Courtney, Atkinson, Moore et al (2014) -
Comparable Autoantibody Serum Levels against Amyloid- and Inflammation-Associated Proteins in Parkinson’s Disease Patients and Controls
PLOS One; DOI: 10.1371/journal.pone.0088604
Maetzler, Apel, Langkamp, et al (2014) -
Amyloid-β Increases Metallo- and Cysteine Protease Activities in Human Macrophages
J Vasc Res.; https://doi.org/10.1159/000356334
Castellano J., Badimon L., Llorente-Cortés V. (2014) -
Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain
Cerebral Cortex; doi: 10.1093/cercor/bhu105.
Jerónimo-Santos, Henriques Vaz, Parreira, et al (2014) -
Molecular Mechanisms of Alzheimer′s Disease Protection by the A673T Allele of Amyloid Precursor Protein
The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.589069.
Maloney, Bainbridge, Gustafson et al (2014) -
Role of amyloid β in the induction of lipolysis and secretion of adipokines from human adipose tissue
Adipocyte; DOI:10.4161/21623945.2014.985020.
Wan, Mah, Simtchouk et al (2014) -
Pituitary adenylate cyclase-activating polypeptide protects against β-amyloid toxicity
Neurobiology of Aging; DOI: 10.1016/j.neurobiolaging.2014.03.022.
Hana, Tanga, Yina et al (2014) -
Synergistic Inhibition of Synaptic Signaling in Cortical Cultures by Subcytotoxic Levels of Oligomerized Amyloid-β and Iron: Alleviation by Zinc
Journal of Alzheimer’s Disease; DOI: 10.3233/JAD-132696.
Marta Anne Taddeo, Sangmook Lee, Thomas B. Shea (2014) -
β-Amyloid peptides display protective activity against the human Alzheimer’s disease-associated herpes simplex virus-1
Biogerontology; DOI 10.1007/s10522-014-9538-8.
Bourgade, Garneau, Giroux et al (2014) -
Nature of the neurotoxic membrane actions of amyloid-β on hippocampal neurons in Alzheimer's disease.
Neurobiol Aging.; doi: 10.1016/j.neurobiolaging.2013.08.035.
Fernando J.Sepúlveda, Humberto Fierro, Eduardo Fernandez, Carolina Castillo, Robert W.Peoples, Carlos Opazo, Luis G.Aguayo (2014) -
ESEEM Analysis of Multi-Histidine Cu(II)-Coordination in Model Complexes, Peptides, and Amyloid-β
The Journal of Physical Chemistry B; DOI: 10.1021/jp500767n.
Silva, Michael, Geib, and Saxena (2014)