Publications

Effects of hydroxyl group variations on a flavonoid backbone toward modulation of metal-free and metal-induced amyloid-β aggregation

Inorganic Chemistry Frontiers; DOI: 10.1039/C5QI00219B

A Novel Liposomal Nanoparticle for the Imaging of Amyloid Plaque by Magnetic Resonance Imaging

IOS Press; DOI: 10.3233/JAD-151124.

Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding

Fluids Barriers CNS; doi: 10.1186/s12987-016-0038-x..

Hippocampal Injections of Oligomeric Amyloid β-peptide (1–42) Induce Selective Working Memory Deficits and Long-lasting Alterations of ERK Signaling Pathway.

Front Aging Neurosci.; doi: 10.3389/fnagi.2015.00245..

Selective inhibition of phosphodiesterases 4, 5 and 9 induces HSP20 phosphorylation and attenuates amyloid beta 1–42-mediated cytotoxicity.

FEBS Open Bio; doi: 10.1002/2211-5463.12156.

Technical performance of a novel, fully automated electrochemiluminescence immunoassay for the quantitation of β-amyloid (1–42) in human cerebrospinal fluid.

Alzheimer’s & Dementia; doi: 10.1016/j.jalz.2015.09.009..

Stabilization of native amyloid β-protein oligomers by Copper and Hydrogen peroxide Induced Cross-linking of Unmodified Proteins (CHICUP).

Biochim Biophys Acta; doi: 10.1016/j.bbapap.2015.12.001.

Bis-pyridylethenyl benzene as novel backbone for amyloid-β binding compounds.

Science Direct; doi:10.1016/j.bmc.2016.05.022

Effect of Copper and Zinc on the Single Molecule Self-Affinity of Alzheimer’s Amyloid-β Peptides.

PLOS ONE; doi: 10.1371/journal.pone.0147488

Reference measurement procedure for CSF amyloid beta (Aβ)1-42 and the CSF Aβ1-42 /Aβ1-40 ratio - a cross-validation study against amyloid PET.

Journal of Neurochem.; doi: 10.1111/jnc.13838..

Ste24p Mediates Proteolysis of Both Isoprenylated and Non-prenylated Oligopeptides.

Journal of Biological Chemistry; doi: 10.1074/jbc.M116.718197.

Comparison of the amyloid pore forming properties of rat and human Alzheimer’s beta-amyloid peptide 1-42: Calcium imaging data.

Data Brief; doi: 10.1016/j.dib.2016.01.019.

Effect of IVIG Formulation on IgG Binding to Self- and Exo- Antigens In Vitro and In Vivo

PLOS ONE; http://dx.doi.org/10.1371/journal.pone.0161826.

Amyloid-b peptides act as allosteric modulators of cholinergic signalling through formation of soluble BA b ACs

Brain; doi: 10.1093/brain/awv318

Quantitative analysis of amyloid polymorphism using height histograms to correct for tip convolution effects in atomic force microscopy imaging.

RSC Advances; DOI:10.1039/C6RA24031C.

Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta

BioMed Central; DOI: 10.1186/s12974-016-0484-z.

Structural insights into mechanisms for inhibiting amyloid β42 aggregation by non-catechol-type flavonoids

Bioorg Med Chem; doi: 10.1016/j.bmc.2015.12.021.

The Alzheimer's-related amyloid beta peptide is internalised by R28 neuroretinal cells and disrupts the microtubule associated protein 2 (MAP-2)

Experimental Eye Research; http://dx.doi.org/10.1016/j.exer.2016.10.013.

A theranostic agent for in vivo near-infrared imaging of β-amyloid species and inhibition of β-amyloid aggregation.

Biomaterials; doi: 10.1016/j.biomaterials.2016.03.047.

Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer’s disease

Acta Neuropathologica; doi: 10.1007/s00401-016-1558-9.