Publications
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Structure-activity relationships for flavone interactions with amyloid β reveal a novel anti-aggregatory and neuroprotective effect of 2′,3′,4′-trihydroxyflavone (2-D08).
Science Direct Bioorganic & Medicinal Chemistry; https://doi.org/10.1016/j.bmc.2017.05.041.
Dylan T. Marsha, Sukanya Dasa, Jessica Ridellb, Scott D. Smida, (2017) -
Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features
Movement Disorders; https://doi.org/10.1002/mds.27232.
Goldman, J.G., Andrews, H., Amara, A., et al (2016) -
The Ketone Body β-Hydroxybutyrate Does Not Inhibit Synuclein Mediated Inflammasome Activation in Microglia
Journal of Neuroimmune Pharmocology; doi: 10.1007/s11481-017-9754-5..
Vandana Deora, Eduardo A. Albornoz, Kevin Zhu, Trent M. Woodruff, Richard Gordon (2016) -
Comparison of Internal Standard Approaches for SRM Analysis of Alpha-Synuclein in Cerebrospinal Fluid
Journal of Proteome Research; 10.1021/acs.jproteome.7b00660.
Patrick Oeckl, Petra Steinacker, and Markus Otto (2016) -
Synthesis and biological evaluation of novel radioiodinated benzimidazole derivatives for imaging α-synuclein aggregates.
Bioorganic & Medicinal Chemistry; https://doi.org/10.1016/j.bmc.2017.10.010.
Watanabe, Ariyoshi, Ozaki, et al (2016) -
Transmission of α-synuclein-containing erythrocyte-derived extracellular vesicles across the blood-brain barrier via adsorptive mediated transcytosis: another mechanism for initiation and progression of Parkinson’s disease?.
Acta Neuropathologica Communications; 10.1186/s40478-017-0470-4.
Matsumoto, J., Stewart, T., Sheng, L. et al. (2016) -
Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles..
PLoS One; https://doi.org/10.1371/journal.pone.0181844.
Marika Doucet, Aadil El-Turabi, Franziska Zabel, Benjamin H.M. Hunn, Nora Bengoa-Vergniory, ilena Cioroch, Mauricio Ramm, Amy M. Smith, Ariane Cruz Gomes, Gustavo Cabral de Miranda, Richard Wade-Martins, Martin F. Bachmann (2016) -
Chromatin-Bound Oxidized α-Synuclein Causes Strand Breaks in Neuronal Genomes in in vitro Models of Parkinson’s Disease
Journal of Alzheimer’s Disease; doi: 10.3233/JAD-170342
Vasquez, Velmarini et al. (2016) -
Endothelin‐converting enzymes degrade α‐synuclein and are reduced in dementia with Lewy bodies.
Journal of Neurochemistry; https://doi.org/10.1111/jnc.13974.
Miners; Love (2016) -
Levodopa (L-DOPA) attenuates endoplasmic reticulum stress response and cell death signaling through DRD2 in SH-SY5Y neuronal cells under α-synuclein-induced toxicity..
Neuroscience; doi: 10.1016/j.neuroscience.2017.06.060..
Juhyun Song, Byeong C.Kim, Dai-Trang T.Nguyen, Manikandan Samidurai, Seong-Min Choib (2016) -
MultiTEP platform–based DNA vaccines for alpha-synucleinopathies: pre clinical evaluation of immunogenicity and therapeutic potency.
Journal of the Alzheimer’s Association; https://doi.org/10.1016/j.neurobiolaging.2017.08.006
Davtyan, Hayk et al. (2016) -
Autoimmune antibody decline in Parkinson’s disease and Multiple System Atrophy; a step towards immunotherapeutic strategies.
Molecular Neurodegeneration; https://doi.org/10.1186/s13024-017-0187-7.
Brudek, T., Winge, K., Folke, J. et al. (2016) -
Recommendations for cerebrospinal fluid collection for the analysis by ELISA of neurogranin trunc P75, α-synuclein, and total tau in combination with Aβ(1–42)/Aβ(1–40)
Alzheimer’s Research & Therapy; https://doi.org/10.1186/s13195-017-0265-7.
Vanderstichele, H., Demeyer, L., Janelidze, S. et al. (2016) -
P2X7 receptor-pannexin 1 interaction mediates extracellular alpha-synuclein-induced ATP release in neuroblastoma SH-SY5Y cells.
Purinergic Signalling; DOI: 10.1007/s11302-017-9567-2.
Wilkaniec, A., Gąssowska, M., Czapski, G.A. et al. (2016) -
An extract of the marine alga Alaria esculenta modulates -synuclein folding and amyloid formation
Elsevier; http://dx.doi.org/10.1016/j.neulet.2017.02.055.
Giffin, Richards, Craft et al (2016) -
Antibodies against the C-terminus of α-synuclein modulate its fibrillation.
Science Direct Biophysical Chemistry Volume 220, January 2017, Pages 34–41; http://dx.doi.org/10.1016/j.bpc.2016.11.002.
Cagla Sahin, Nikolai Lorenzen, Lasse Lemminger, Gunna Christiansen, Ian Max Møller, Louise Buur Vesterager, Lars Østergaard Pedersen, Karina Fog, Pekka Kallunki, Daniel E. Otzen (2016) -
Behavior of α‐synuclein–drug complexes during nanopore analysis with a superimposed AC field
Electrophoresis; doi: 10.1002/elps.201600253.
Elisabet Jakova, Jeremy S. Lee (2016) -
DOPAL is transmissible to and oligomerizes alpha-synuclein in human glial cells
Auton Neurosci; doi: 10.1016/j.autneu.2015.12.008.
Jinsmaa, Sullivan, Sharabi, et al (2016) -
FTY720 (Fingolimod) reverses α-synuclein-Induced downregulation of brain-derived neurotrophic factor mRNA in OLN-93 oligodendroglial cells.
Neuropharmacology; http://dx.doi.org/10.1016/j.neuropharm.2017.01.028.
Segura-Ulate, Yang, Vargas-Medrano, Perez (2016) -
Aging African green monkeys manifest transcriptional, pathological, and cognitive hallmarks of human Alzheimer’s disease
Neurobiology of Aging; https://doi.org/10.1016/j.neurobiolaging.2017.12.011.
Cramer, Gentzel, Tanis, et al (2016)
