Publications
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Amyloidogenicity and toxicity of the reverse and scrambled variants of amyloid‐β 1‐42.
FEBS Letters; https://doi.org/10.1002/1873-3468.12590.
Vadukul , Gbajumo , Marshall , et al (2017) -
Covalent modifications of the amyloid beta peptide by hydroxynonenal: Effects on metal ion binding by monomers and insights into the fibril topology.
Journal of Inorganic Biochemistry; DOI: 10.1016/j.jinorgbio.2017.06.007.
G.Grasso, P.H.Axelsen, H.Komatsu (2017) -
Carbon Nanodot‐Sensitized Modulation of Alzheimer's β‐Amyloid Self‐Assembly, Disassembly, and Toxicity.
Small; doi: 10.1002/smll.201700983.
You Jung Chung, Kayoung Kim, Byung Il Lee, Chan Beum Park (2017) -
PROGRESS ON THE DEVELOPMENT OF CERTIFIED REFERENCE MATERIALS FOR Aβ1-42.
Journal of the Alzheimer’s Association; https://doi.org/10.1016/j.jalz.2017.07.629.
Boulo, Kuhlmann, Leinenbach et al (2017) -
Coconut oil protects cortical neurons from amyloid beta toxicity by enhancing signaling of cell survival pathways.
Science Direct Neurochemistry International; http://dx.doi.org/10.1016/j.neuint.2017.01.008.
F. Nafar, J.P. Clarke , K.M. Mearow (2017) -
Assessment of Novel Curcumin Derivatives as Potent Inhibitors of Inflammation and Amyloid-β Aggregation in Alzheimer’s Disease.
Journal of Alzheimer’s Disease; doi: 10.3233/JAD-170071.
Lakey-Beitia Johana, González Yisettb, Doens, Deborah, Stephens David E., Santamaría Ricardo, Murillo Enriquee, Gutiérrez Marcelino, Fernández Patricia L, Rao, K.S., Larionov Oleg V., Durant-Archibold Armando A, (2017) -
Microglial Activation Results in Inhibition of TGF-β-Regulated Gene Expression.
J Mol Neurosci.; doi: 10.1007/s12031-017-0980-3.
Kwame Ofori Affram, Kendall Mitchell, Aviva J. Symes (2017) -
Inhibition of PDE2 reverses beta amyloid induced memory impairment through regulation of PKA/PKG-dependent neuro-inflammatory and apoptotic pathways.
Scientific Reports; https://doi.org/10.1038/s41598-017-08070-2.
Li Wang, Yilixiati Xiaokaiti, Gang Wang, Xiaoxiao Xu, Ling Chen, Xianfeng Huang, Li Liu, Jianchun Pan, Shuqun Hu, Zhuoyou Chen, Ying Xu (2017) -
Folding and Misfolding of Amyloid-β40 and 42 in Alzheimer’s Disease.
Biophysics and Biochemistry of Protein Aggregation; https://doi.org/10.1142/9789813202382_0007.
Yu-Jen Chang, Yun-Ru Chen (2017) -
Retro-inverso peptide inhibitor nanoparticles as potent inhibitors of aggregation of the Alzheimer's Aβ peptide.
Nanomedicine: Nanotechnology, Biology and Medicine; https://doi.org/10.1016/j.nano.2016.10.006.
Maria Gregori, Mark Taylor, Elisa Salvati, Simona Mancini, Claudia Balducci, Gianluigi Forloni, Vanessa Zambelli , Massimo Masserini, David Allsop (2017) -
P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of Alzheimer's disease.
Europe PMC; doi: 10.1016/j.neuropharm.2017.10.027.
Sáez-Orellana, Francisco, Fuentes-Fuentes, María C, Godoy, Pamela A, Silva-Grecchi, Tiare, Panes, Jessica D,…..Aguayo, Luis G. (2017) -
Structure-activity relationships for flavone interactions with amyloid β reveal a novel anti-aggregatory and neuroprotective effect of 2′,3′,4′-trihydroxyflavone (2-D08).
Science Direct Bioorganic & Medicinal Chemistry; https://doi.org/10.1016/j.bmc.2017.05.041.
Dylan T. Marsha, Sukanya Dasa, Jessica Ridellb, Scott D. Smida, (2017) -
Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features
Movement Disorders; https://doi.org/10.1002/mds.27232.
Goldman, J.G., Andrews, H., Amara, A., et al (2016) -
The Ketone Body β-Hydroxybutyrate Does Not Inhibit Synuclein Mediated Inflammasome Activation in Microglia
Journal of Neuroimmune Pharmocology; doi: 10.1007/s11481-017-9754-5..
Vandana Deora, Eduardo A. Albornoz, Kevin Zhu, Trent M. Woodruff, Richard Gordon (2016) -
Comparison of Internal Standard Approaches for SRM Analysis of Alpha-Synuclein in Cerebrospinal Fluid
Journal of Proteome Research; 10.1021/acs.jproteome.7b00660.
Patrick Oeckl, Petra Steinacker, and Markus Otto (2016) -
Synthesis and biological evaluation of novel radioiodinated benzimidazole derivatives for imaging α-synuclein aggregates.
Bioorganic & Medicinal Chemistry; https://doi.org/10.1016/j.bmc.2017.10.010.
Watanabe, Ariyoshi, Ozaki, et al (2016) -
Transmission of α-synuclein-containing erythrocyte-derived extracellular vesicles across the blood-brain barrier via adsorptive mediated transcytosis: another mechanism for initiation and progression of Parkinson’s disease?.
Acta Neuropathologica Communications; 10.1186/s40478-017-0470-4.
Matsumoto, J., Stewart, T., Sheng, L. et al. (2016) -
Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles..
PLoS One; https://doi.org/10.1371/journal.pone.0181844.
Marika Doucet, Aadil El-Turabi, Franziska Zabel, Benjamin H.M. Hunn, Nora Bengoa-Vergniory, ilena Cioroch, Mauricio Ramm, Amy M. Smith, Ariane Cruz Gomes, Gustavo Cabral de Miranda, Richard Wade-Martins, Martin F. Bachmann (2016) -
Chromatin-Bound Oxidized α-Synuclein Causes Strand Breaks in Neuronal Genomes in in vitro Models of Parkinson’s Disease
Journal of Alzheimer’s Disease; doi: 10.3233/JAD-170342
Vasquez, Velmarini et al. (2016) -
Endothelin‐converting enzymes degrade α‐synuclein and are reduced in dementia with Lewy bodies.
Journal of Neurochemistry; https://doi.org/10.1111/jnc.13974.
Miners; Love (2016)