Publications
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Decoding the synaptic dysfunction of bioactive human AD brain soluble Aβ to inspire novel therapeutic avenues for Alzheimer’s disease
Acta Neuropathologica Communications; https://doi.org/10.1186/s40478-018-0626-x.
Shaomin Li, Ming Jin, Lei Liu, Yifan Dang, Beth L. Ostaszewski and Dennis J. Selkoe (2018) -
Effect of Varying Concentrations of Docosahexaenoic Acid on Amyloid Beta (1–42) Aggregation: An Atomic Force Microscopy Study.
Molecules; https://doi.org/10.3390/molecules23123089.
Lee, B.Y., Attwood, S.J., Turnbull, S., Leonenko, Z. (2018) -
Amyloid-β Inhibits PDGFβ Receptor Activation and Prevents PDGF-BB-induced Neuroprotection.
Current Alzheimer Research; https://doi.org/10.2174/1567205015666180110110321.
Liu, Hui; Saffi, Golam T.; Vasefi, Maryam S.; Choi, Youngjik; Kruk, Jeff S.; Ahmed, Nawaz; Gondora, Nyasha; Mielke, John; Leonenko, Zoya; Beazely, Michael A (2018) -
Pharmacological Modulation of Three Modalities of CA1 Hippocampal Long-Term Potentiation in the Ts65Dn Mouse Model of Down Syndrome
Neural Plasticity; 10.1155/2018/9235796.
Jonah J. Scott-McKean, Adriano L. Roque, Krystyna Surewicz, Mark W. Johnson, Witold K. Surewicz, and Alberto C. S. Costa (2018) -
Effects of Prion Protein on Aβ42 and Pyroglutamate-Modified AβpΕ3-42 Oligomerization and Toxicity
Molecular Neurobiology; DOI: https://doi.org/10.1007/s12035-018-1202-x.
Katiuscia Pagano, Denise Galante, Cristina D’Arrigo, Alessandro Corsaro, Mario Nizzari, Tullio Florio, Henriette Molinari, Simona Tomaselli, Laura Ragona (2018) -
Development of an aggregate-selective, human-derived α-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models.
Neurobiology of Disease; https://doi.org/10.1016/j.nbd.2018.10.016.
Weihofen, Liu, Arndt, et al (2017) -
Phenylindanes in Brewed Coffee Inhibit Amyloid-Beta and Tau Aggregation.
Frontiers; https://doi.org/10.3389/fnins.2018.00735.
Ross S. Mancini, Yanfei Wang, and Donald F. Weaver (2017) -
Monitoring α-synuclein multimerization in vivo..
FASEB Journal; https://doi.org/10.1096/fj.201800148RRR.
Vibha Prasad, Yasmine Wasser, Friederike Hans, Anand Goswami, Istvan Katona, Tiago F. Outeiro, Philipp J. Kahle, Jörg B. Schulz, and Aaron Voigt (2017) -
Cerebrospinal Fluid Total and Phosphorylated α-Synuclein in Patients with Creutzfeldt–Jakob Disease and Synucleinopathy
Molecular Neurobiology; doi: 10.1007/s12035-018-1313-4.
Schmitz,Villar-Piqué, Llorens, et al (2017) -
Extending the functional characteristics of naturally occurring autoantibodies against β-Amyloid, Prion Protein and α-Synuclein.
PLOS ONE; https://doi.org/10.1371/journal.pone.0202954.
Alexandra Albus, Maike Gold, Jan-Philipp Bach, Monika Burg-Roderfeld, Marit Jördens, Yvonne Kirchhein, Yannick Kronimus, David Mengel, Inga Zerr, Richard Dodel (2017) -
Native Top-Down Mass Spectrometry and Ion Mobility MS for Characterizing the Cobalt and Manganese Metal Binding of α-Synuclein Protein.
J Am Soc Mass Spectrom.; doi: 10.1007/s13361-018-2002-2.
Wongkongkathep, P., Han, J., Choi,T., Yin, S., Kim,H., Loo,J. (2017) -
α‐Synuclein activates innate immunity but suppresses interferon‐γ expression in murine astrocytes
Eur J Neurosci.; https://doi.org/10.1111/ejn.13956.
Jintang Wang Zheng Chen Jeremy D. Walston Peisong Gao Maolong Gao Sean X. Leng (2017) -
Extracellular Alpha-Synuclein Oligomers Induce Parkin S-Nitrosylation: Relevance to Sporadic Parkinson’s Disease Etiopathology
Molecular Neurobiology; 10.1007/s12035-018-1082-0.
Wilkaniec, A., Lenkiewicz, A.M., Czapski, G.A. et al. (2017) -
Integrin CD11b mediates α-synuclein-induced activation of NADPH oxidase through a Rho-dependent pathway
Redox Biology; https://doi.org/10.1016/j.redox.2017.11.010.
Liyan Hou, Xiuqi Bao, Caixia Zang, Hanyu Yang, Fuqiang Sun, Yuning Che, Xuefei Wu, Shao Li, Dan Zhang, Qingshan Wang (2017) -
Alpha-synuclein alters differently gene expression of Sirts, PARPs and other stress response proteins: implications for neurodegenerative disorders..
Molecular Neurobiology; https://doi.org/10.1007/s12035-016-0317-1.
Motyl, J., Wencel, P.L., Cieślik, M. Strosznajder,R.P., Strosznajder,J.B. (2017) -
Calpain-mediated tau fragmentation is altered in Alzheimer’s disease progression.
Scientific Reports; DOI:10.1038/s41598-018-35130-y.
Hsu-Hsin Chen, Peter Liu, Paul Auger, Seung-Hye Lee, Oskar Adolfsson, Lorianne Rey-Bellet, Julien Lafrance-Vanasse, Brad A. Friedman, Maria Pihlgren, Andreas Muhs, Andrea Pfeifer, James Ernst, Gai Ayalon, Kristin R. Wildsmith, Thomas G. Beach & Marcel P. van der Brug (2017) -
In vitro generation of tau aggregates conformationally distinct from parent tau seeds of Alzheimer’s brain
Prion; https://doi.org/10.1080/19336896.2018.1545524.
Won-Hee Nam & Young Pyo Choi (2017) -
Secretion of Tau via an Unconventional Non-vesicular Mechanism
Cell Reports; https://doi.org/10.1016/j.celrep.2018.10.078.
Merezhko, M., Brunello, C.A., Yan, X., et al (2017) -
Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy
Mol Neurodegeneration 15, 2 (2020). https://doi.org/10.1186/s13024-019-0354-0
Chen, X., Li, Y., Wang, C. et al. (2017) -
Anti-Tau Antibodies Based Electrochemical Sensor for Detection of Tau Protein Biomarkers.
Journal of The Electrochemical Society; DOI: 10.1149/2.0041812jes.
Nicholas Carlin and Sanela Martic-Milne (2017)