Publications
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Resveratrol alleviates motor and cognitive deficits and neuropathology in the A53T α-synuclein mouse model of Parkinson's disease.
Food & Function; DOI: 10.1039/c8fo00964c.
Li-fan Zhang, Xiao-lin Yu, Mei Ji, Shu-ying Liu, Xiao-ling Wu, Yu-jiong Wang, Rui-tian Liu (2018) -
α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome.
Experimental and Therapeutic Medicine; https://doi.org/10.3892/etm.2019.8297.
Wang,X., Chi,J., Huang,D., Ding,L., Zhao,X., Jiang,L., Yu,Y., Gao,F. (2018) -
Effects of single and combined immunotherapy approach targeting amyloid β protein and α-synuclein in a dementia with Lewy bodies-like model..
Alzheimers Dement.; doi: 10.1016/j.jalz.2019.02.002.
Markus Mandler, Edward Rockenstein, Cassia Overk, Michael Mante, Jazmin Florio, Anthony Adame, Changyoun Kim, Radmila Santic, Achim Schneeberger, Frank Mattner, Sabine Schmidhuber, Gergan Galabova, Brian Spencer, Eliezer Masliah, Robert A.Rissman (2018) -
TREM2 deficiency aggravates α-synuclein–induced neurodegeneration and neuroinflammation in Parkinson’s disease models
FASEB J.; DOI: 10.1096/fj.201900992R.
Guo, Wei, Yan, et al (2018) -
Functionalization of the TMEM175 p.M393T Variant as a risk factor for Parkinson Disease
Hum Mol Genet.; DOI: 10.1093/hmg/ddz136.
Jinn, Blauwendraat, Toolan, et al (2018) -
Increased Immune Activation by Pathologic α‐Synuclein in Parkinson's Disease.
Annals of Neurology; https://doi.org/10.1002/ana.25557.
Grozdanov, Bousset, Hoffmeister, et al (2018) -
Effect of naturally occurring α-synuclein-antibodies on toxic α-synuclein-fragments.
Neuroscience Letters; https://doi.org/10.1016/j.neulet.2019.04.004
Rabenstein, Besong, Wolfah, et al (2018) -
Reduction of Immunoreactivity Against the C-Terminal Region of the Intracellular α-Synuclein by Exogenous α-Synuclein Aggregates: Possibility of Conformational Changes..
Journal of Parkinson’s Disease; doi: 10.3233/JPD-160835..
Izumi Yasuhiko, Kondo, Naoto, Takahashi Ryosuke, Akaike Akinori, Kume Toshiaki (2018) -
Identification of a New α-Synuclein Aggregation Inhibitor via Mass Spectrometry Based Screening.
ACS Chem. Neurosci.; https://doi.org/10.1021/acschemneuro.9b00092.
Mingming Xu, Wendy Loa-Kum-Cheung, Haiyan Zhang, Ronald J. Quinn, George D. Mellick (2018) -
Interferon-γ Potentiates α-Synuclein-induced Neurotoxicity Linked to Toll-like Receptors 2 and 3 and Tumor Necrosis Factor-α in Murine Astrocytes..
Mol Neurobiol.; DOI: 10.1007/s12035-019-1567-5.
Jintang Wang, Zheng Chen, Jeremy D. Walston, Peisong Gao, Maolong Gao, Sean X. Leng (2018) -
Characterization of pathology-inducing α-synuclein species from human diseased brain tissue.
bioRxiv; doi: https://doi.org/10.1101/588335.
John D. Graef, Nina Hoque, Craig Polson, Ling Yang, Lawrence Iben, Yang Cao, Nino Devidze, Michael K. Ahlijanian, Jere E. Meredith Jr. (2018) -
Electrochemical Detection of Interaction between Copper(II) and Peptides Related to Pathological α-Synuclein Mutants.
Anal Chem.; DOI: 10.1021/acs.analchem.8b03612.
ShaoPei Li, Kagan Kerman (2018) -
Novel Mannitol-Based Small Molecules for Inhibiting Aggregation of α-Synuclein Amyloids in Parkinson's Disease.
Frontiers; https://doi.org/10.3389/fmolb.2019.00016.
Ashim Paul, Bo-Dou Zhang, Satabdee Mohapatra, Gao Li, Yan-Mei Li, Ehud azit, and Daniel Segal (2018) -
Proline- and Arginine-Rich Peptides as Flexible Allosteric Modulators of Human Proteasome Activity.
Journal of Medicinal Chemistry; DOI: 10.1021/acs.jmedchem.8b01025
Gizyṅska, Witkowska, Karpowicz, et al. (2018) -
Protein Damage in Aging and Age-Related Diseases.
Open Biology; https://doi.org/10.1098/rsob.180249
Miroslav Radman, Anita Krisko (2018) -
Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity.
Springer Berlin Heidelberg; https://doi.org/10.1007/s00401-019-01993-2.
Di Hu, Xiaoyan Sun, Xudong Liao, Xinwen Zhang, Sara Zarabi,..Xin Qi (2018) -
Heterogeneity in gut microbiota drive polyphenol metabolism that influences α-synuclein misfolding and toxicity.
The Journal of Nutritional Biochemistry; https://doi.org/10.1016/j.jnutbio.2018.10.019.
Lap Ho, Danyue Zhao, Kenjiro Ono, Kai Ruan, Ilaria Mogno, Mayumi Tsuji, Eileen Carry, Justin Brathwaite, Steven Sims, Tal Frolinger, Susan Westfall, Paolo Mazzola, Qingli Wu, Ke Hao, Thomas E. Lloyd, James E. Simon, Jeremiah Faith, Giulio M. Pasinetti (2018) -
Measuring Mitochondrial Dysfunction Caused by Soluble α-Synuclein Oligomers.
Humana Press, New York, NY; https://doi.org/10.1007/978-1-4939-9124-2_14.
Eric S. Luth, Irina G. Stavrovskaya (2018) -
Seeding variability of different alpha synuclein strains in synucleinopathies.
Annals of Neurology; https://doi.org/10.1002/ana.25446.
Candelise, Schmitz, Llorens et al (2018) -
Extracellular Alpha-Synuclein Oligomers Induce Parkin S-Nitrosylation: Relevance to Sporadic Parkinson’s Disease Etiopathology.
Springer; https://doi.org/10.1007/s12035-018-1082-0.
Anna Wilkaniec, Anna M. Lenkiewicz, Grzegorz A. Czapski, Henryk M. Jęśko, Wojciech Hilgier, Robert Brodzik, Magdalena Gąssowska-Dobrowolska, Carsten Culmsee, Agata Adamczyk (2018)
