Publications
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Interferon-γ Potentiates α-Synuclein-induced Neurotoxicity Linked to Toll-like Receptors 2 and 3 and Tumor Necrosis Factor-α in Murine Astrocytes..
Mol Neurobiol.; DOI: 10.1007/s12035-019-1567-5.
Jintang Wang, Zheng Chen, Jeremy D. Walston, Peisong Gao, Maolong Gao, Sean X. Leng (2018) -
Characterization of pathology-inducing α-synuclein species from human diseased brain tissue.
bioRxiv; doi: https://doi.org/10.1101/588335.
John D. Graef, Nina Hoque, Craig Polson, Ling Yang, Lawrence Iben, Yang Cao, Nino Devidze, Michael K. Ahlijanian, Jere E. Meredith Jr. (2018) -
Electrochemical Detection of Interaction between Copper(II) and Peptides Related to Pathological α-Synuclein Mutants.
Anal Chem.; DOI: 10.1021/acs.analchem.8b03612.
ShaoPei Li, Kagan Kerman (2018) -
Novel Mannitol-Based Small Molecules for Inhibiting Aggregation of α-Synuclein Amyloids in Parkinson's Disease.
Frontiers; https://doi.org/10.3389/fmolb.2019.00016.
Ashim Paul, Bo-Dou Zhang, Satabdee Mohapatra, Gao Li, Yan-Mei Li, Ehud azit, and Daniel Segal (2018) -
Proline- and Arginine-Rich Peptides as Flexible Allosteric Modulators of Human Proteasome Activity.
Journal of Medicinal Chemistry; DOI: 10.1021/acs.jmedchem.8b01025
Gizyṅska, Witkowska, Karpowicz, et al. (2018) -
Protein Damage in Aging and Age-Related Diseases.
Open Biology; https://doi.org/10.1098/rsob.180249
Miroslav Radman, Anita Krisko (2018) -
Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity.
Springer Berlin Heidelberg; https://doi.org/10.1007/s00401-019-01993-2.
Di Hu, Xiaoyan Sun, Xudong Liao, Xinwen Zhang, Sara Zarabi,..Xin Qi (2018) -
Heterogeneity in gut microbiota drive polyphenol metabolism that influences α-synuclein misfolding and toxicity.
The Journal of Nutritional Biochemistry; https://doi.org/10.1016/j.jnutbio.2018.10.019.
Lap Ho, Danyue Zhao, Kenjiro Ono, Kai Ruan, Ilaria Mogno, Mayumi Tsuji, Eileen Carry, Justin Brathwaite, Steven Sims, Tal Frolinger, Susan Westfall, Paolo Mazzola, Qingli Wu, Ke Hao, Thomas E. Lloyd, James E. Simon, Jeremiah Faith, Giulio M. Pasinetti (2018) -
Measuring Mitochondrial Dysfunction Caused by Soluble α-Synuclein Oligomers.
Humana Press, New York, NY; https://doi.org/10.1007/978-1-4939-9124-2_14.
Eric S. Luth, Irina G. Stavrovskaya (2018) -
Seeding variability of different alpha synuclein strains in synucleinopathies.
Annals of Neurology; https://doi.org/10.1002/ana.25446.
Candelise, Schmitz, Llorens et al (2018) -
Extracellular Alpha-Synuclein Oligomers Induce Parkin S-Nitrosylation: Relevance to Sporadic Parkinson’s Disease Etiopathology.
Springer; https://doi.org/10.1007/s12035-018-1082-0.
Anna Wilkaniec, Anna M. Lenkiewicz, Grzegorz A. Czapski, Henryk M. Jęśko, Wojciech Hilgier, Robert Brodzik, Magdalena Gąssowska-Dobrowolska, Carsten Culmsee, Agata Adamczyk (2018) -
Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess α-Synuclein at Synapses.
Journal of Neuroscience; https://doi.org/10.1101/517524.
Susan M.L. Banks, Audrey T. Medeiros, Molly McQuillan, David J. Busch, Ana Sofia Ibarraran-Viniegra, Subhojit Roy, Rui Sousa, Eileen M. Lafer, Jennifer R. Morgan (2018) -
Quantification of Tau Protein Lysine Methylation in Aging and Alzheimer’s Disease.
J Alzheimers Dis.; doi: 10.3233/JAD-190604.
Huseby, Carol J., Hoffman, Claire N., Cooper, Grace L., Cocuron, Jean-Christophe., Alonso, Ana P., Thomas, Stefani N., Yang, Austin J., Kuret, J. (2018) -
Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation.
J Biol Chem.; doi: 10.1074/jbc.RA119.009487.
Takashi Saito, Naomi Mihira, Yukio Matsuba, Hiroki Sasaguri, Shoko Hashimoto, Sneha Narasimhan,Bin Zhang, Shigeo Murayama,Makoto Higuchi, Virginia M.Y. Lee, John Q Trojanowski, Takaomi C. Saido (2018) -
Highly sensitive quantification of Alzheimer's disease biomarkers by aptamer-assisted amplification.
Theranostics; DOI: 10.7150/thno.29232.
Hei-Nga Chan, Di Xu, See-Lok Ho, Dinggeng He, Man Shing Wong, Hung-Wing Li (2018) -
Mass Spectrometry-Based Quantification of Tau in Human Cerebrospinal Fluid Using a Complementary Tryptic Peptide Standard.
Journal of Proteome Research; https://doi.org/10.1021/acs.jproteome.8b00920.
Maotian Zhou, Duc M Duong, Erik C.B. Johnson, Jingting Dai, James J Lah, Allan I. Levey, and Nicholas T. Seyfried (2018) -
ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects.
Nature Communications; https://doi.org/10.1038/s41467-019-09291-x.
Yuanyuan Zhao, Xiaoyan Sun, Di Hu, Domenick A. Prosdocimo, Charles Hoppel, Mukesh K. Jain, Rajesh Ramachandran & Xin Qi (2018) -
Dural lymphatics regulate clearance of extracellular tau from the CNS.
BioMed Central; https://doi.org/10.1186/s13024-019-0312-x.
Tirth K. PatelLeMoyne Habimana-GriffinXuefeng GaoBaogang XuSamuel Achilefu,....David M. Holtzman (2018) -
Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors.
Science Advances; DOI: 10.1126/sciadv.aau3333
Stephen S. Dominy, Casey lynch, Florian Ermini, Malgorzata Benedyk, Agata Marczyk,...Jan Potempa (2018) -
Amyloid-β/Drug Interactions from Computer Simulations and Cell-Based Assays
IOS Press; DOI 10.3233/JAD-179902.
Nguyen, Phuong H., del Castillo-Frias, Maria P., Berthoumieux, Olivia ,Faller, Peter, Doig, Andrew J., Derreumaux, Philippe (2018)
