Proline- and Arginine-Rich Peptides as Flexible Allosteric Modulators of Human Proteasome Activity.
Journal of Medicinal Chemistry; DOI: 10.1021/acs.jmedchem.8b01025
Protein Damage in Aging and Age-Related Diseases.
Open Biology; https://doi.org/10.1098/rsob.180249
Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity.
Springer Berlin Heidelberg; https://doi.org/10.1007/s00401-019-01993-2.
Heterogeneity in gut microbiota drive polyphenol metabolism that influences α-synuclein misfolding and toxicity.
The Journal of Nutritional Biochemistry; https://doi.org/10.1016/j.jnutbio.2018.10.019.
Measuring Mitochondrial Dysfunction Caused by Soluble α-Synuclein Oligomers.
Humana Press, New York, NY; https://doi.org/10.1007/978-1-4939-9124-2_14.
Seeding variability of different alpha synuclein strains in synucleinopathies.
Annals of Neurology; https://doi.org/10.1002/ana.25446.
Extracellular Alpha-Synuclein Oligomers Induce Parkin S-Nitrosylation: Relevance to Sporadic Parkinson’s Disease Etiopathology.
Springer; https://doi.org/10.1007/s12035-018-1082-0.
Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess α-Synuclein at Synapses.
Journal of Neuroscience; https://doi.org/10.1101/517524.
Development of an aggregate-selective, human-derived α-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models.
Neurobiology of Disease; https://doi.org/10.1016/j.nbd.2018.10.016.
Phenylindanes in Brewed Coffee Inhibit Amyloid-Beta and Tau Aggregation.
Frontiers; https://doi.org/10.3389/fnins.2018.00735.