FK-506

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Product Name
FK-506
Size
Catalog #
N-3024-1
Storage
-20°C
Description
FK-506 induces immunosuppression by inhibiting T cell proliferation. Inhibits FKBP12 and calcineurin (IC50ca. 1 nM)1. Reduces neuroinflammation and neuro-degeneration in an alpha-synuclein-based rat model of Parkinson’s disease2. Increases the rate of axonal regeneration following crush injury in a rat model3. Cell permeable.
Molecular Mass
804.0
Purity
>98%
Cost (US$)
$100
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1.DY Yu et al. IUBMB Life 2006 58:429
2.A Van Der Perren et al. Neurobiol. Aging 2015 36:155
3.HH Sun et al. Neuroscience 2012 223:114