Captopril

Angiotensin-converting enzyme (ACE) inhibitor (IC50 = 0.022 μM). Also inhibits the bifunctional Zn2+-containing leukotriene A4 hydrolase/aminopeptidase (LTA4 hydrolase) reversibly and competitively (Ki = 6.0 μM for leukotriene B4 formation and Ki = 60 nM for L-lysine-p-nitroanilide). Displays vasodilatory and antihypertensive effects in vivo. Clinically useful antihypertensive agent.

Catalog ID: CV-1020-2

$152.00

  • Product Details

    • Size: 5 g
    • Physical State: White powder
    • Temperature Storage: -20°C
    • Temperature Shipping: Ambient
    • Molecular Mass: 217.3
  • References

    1. Cushman, D.W., et al., (1999) Nat. Med., 5 : 1110
    2. Orning, L., et al., (1991) J. Biol. Chem., 266 : 16507