Na Valproate
Histone deacetylase inhibitor (IC50=400 µM). Demonstrates neuroprotective, anticancer and anti-inflammatory activity. Inhibits Aβ production, reduced neuritic plaque formation and improved memory deficits in Alzheimer’s mouse models. Improves stem cell reprogramming efficiency and enables efficient induction of pluripotency without introduction of the oncogene c-Myc. Clinically useful anticonvulsant.
$57.00
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Product Details
- Size: 5 g
- Physical State: White powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Molecular Mass: 166.2
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References
1. Phiel, C.J., et al., (2001) J. Biol. Chem., 276 : 36734
2. Kim, H.J., et al., (2007) J. Pharmacol. Exp. Ther., 321 : 892
3. Qing, H., et al., (2008) J. Exp. Med., 205 : 2781
4. Huangfu, D., et al., (2008) Nature Biotechnol., 26 : 795
