Tau K19, C322S Mutant
Product background: The Tau proteins are a family of neuronal microtubule associated proteins that are found in the neurofibrillary tangles often associated with Alzheimer’s Disease. Tau promotes the assembly and maintains the structure of microtubules in neuronal cells.
About the product: This Tau K19 fragment comprises the microtubule binding region of Tau with repeat 2 omitted and the mutation C322S. Expressed recombinantly in E. coli, Tau K19 is purified to our highest standards to ensure batch-to-batch consistency in both purity and quality.
Applications: rPeptide Tau products may be used for a wide variety of applications including aggregation experiments, microtubule binding studies and acetyltransferase activity.
$425.00 – $5,120.00
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Product Details
- Physical State: White lyophilized powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Source: Recombinant. Tau K19 is comprised of amino acids Q244-V275 plus V306-E372 from the full-length human Tau sequence, with a mutation C322S.
- Purity: >90% by SDS-PAGE and Mass spec.
- Molecular Mass: 10,650 Da
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References
1. Shammas S., et al., (2015) Nat Commun., 7025 (6)
2. Kim D., et al., (2015) Sci Rep. 5 : 15231
3. Mukrasch MD., et al., (2005) J Biol Chem. 280(26) : 24978-24986
4. Cohen TJ., et al., (2013) Nat Struct Mol Biol. 20(6) : 756-762
