Fluorescein Beta-Amyloid (1-42)
Product background: Beta-Amyloid peptides (A-beta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be a primary contributor to Alzheimer’s Disease (AD).
About the product: Beta-Amyloid (1-42) FITC is a synthetic peptide with an FIuorescein Isothiocyanate attached to the N-terminus, and purified to our highest standards to ensure batch-to-batch consistency in both purity and quality.
Applications: This FITC labeled form of Beta-Amyloid (1-42) is ideally suited to localization experiments, aggregation monitoring and other fluorescence based studies without the need for mutations or further labeling.
$650.00 – $900.00
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Product Details
- Physical State: White lyophilized powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Sequence:
Fluorescein-D A E F R H D S G Y E V H H Q K L V F F A E D V G S N K G A I I G L M V G G V V I A
- Source: Synthetic peptide
- Purity: >95%
- Molecular Mass: 4,873.4 Da
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References
1. Wei, H., et al. (2000) J. Pharmacol. 392: 117
2. Yankner, B.A., et al., (1990) Science, 250: 279-282
3. Selkoe, D.J., (2001) Physiol. Rev, 81: 741-766
4. Stine, W.B., et al., (2003) J. Biol. Chem, 278: 11612-11622
5. Frank, R.A., et al., (2003) Neurobiology of Aging, 24: 521-536 -
Publications
CD22 modulation alleviates amyloid β-induced neuroinflammation
J Neuroinflammation (2025) 22 (1), 32 DOI: 10.1186/s12974-025-03361-2
Mural cell dysfunction leads to altered cerebrovascular tau uptake following repetitive head trauma
ScienceDirect; https://doi.org/10.1016/j.nbd.2020.105237
Cell Reports; https://doi.org/10.1016/j.celrep.2021.108835
ScienceDirect; https://doi.org/10.1016/j.nbd.2020.105146
