Alpha-Synuclein 2G9 Antibody

Product background: Alpha-Synuclein (α-Synuclein) is a presynaptic protein found to be a major component of Parkinson’s Disease (PD) aggregates and is implicated in the pathogenesis of PD and related neurodegenerative disorders.

About the product: Alpha-Synuclein 2G9 is an rPeptide exclusive mouse monoclonal antibody that binds most of the Alpha-Synuclein proteins. This antibody does not recognize the Alpha-Synuclein 1-60, 1-95, or NACP splicing variant, indicating the epitope is located near the C-terminus.

Applications: This anti-Alpha-Synuclein mouse derived monoclonal antibody recognizes all but three Alpha-Synuclein constructs. Possible applications may include isoform identification, qualitative analysis, or expression level monitoring through western blots, ELISAs, or other methods.

Catalog ID: SAb-1002

$200.00 – $1,280.00

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  • Product Details
    • Host: Mouse
    • Reactivity Species: Human
    • Physical State: Liquid
    • Temperature Storage: -80°C
    • Temperature Shipping: Dry Ice
    • Purity: >90% by SDS-PAGE

  • References

    1. Conway, K., et al., (2000) Biochemistry, 39 : 2552
    2. Jakes, R., et al., (1994) FEBS Letters, 345 : 27
    3. Masliah, E., et al., (2001) Proc. Natl. Acad. Sci., USA, 98 : 12245
    4. Ueda, K., et al., (1993) Proc. Natl. Acad. Sci., USA, 90 : 11282
    5. Grozdanov, V., et al., (2019) Ann Neurol, 86(4) : 593-606

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