Salirasib

Displaces active Ras protein from the plasma membrane inhibiting its activity, IC50=10-15 µM 1. Enhances autophagy in a variety of cell lines 2. Protects against HIV-1-induced accumulation of Aβ in human brain microvascular endothelial cells 3. Displays antiinflammatory activity, inhibiting the release of PGD2 and TNFα from mast cells 4.

Catalog ID: N-1461-2

$228.00

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  • Product Details
    • Size: 25.0 mg
    • Physical State: White crystalline powder
    • Temperature Storage: -20°C
    • Temperature Shipping: Ambient
    • Molecular Mass: 358.5

  • References

    1. Haklai, R., et al., (1998) Biochemistry, 37 : 1306
    2. Schmuckler, E., et al., (2013) Oncotarget, 4 : 145
    3. Andras, I.E., et al., (2012) Biochem. Biophys. Res. Commun., 421 : 177
    4. Mor, A., et al., (2011) Inflammation, 34 : 314

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