Alpha-Synuclein 98 Monomer

Product Background: Alpha-Synuclein (α-Synuclein) is a presynaptic protein found to be a major component of Parkinson’s Disease (PD) aggregates and is implicated in the pathogenesis of PD and related neurodegenerative disorders.

About the product: Expressed recombinantly in E. coli, Alpha-Synuclein 98 is a splicing variant that lacks exons 3 (G41-T54) and 5 (N103-E130) and is purified to our highest standards to ensure batch-to-batch consistency in both purity and quality. 

Applications: Human Alpha-Synuclein 98 is sold in 20mM Tris, pH 7.4 to ensure a highly monomeric starting material that may be suited to aggregation studies, seeding experiments, molecular standards, and more.

Catalog ID: S-1026

Price range: $300.00 through $550.00

Download Datasheet

  • Product Details
    • Physical State: White lyophilized powder
    • Temperature Storage: -20°C
    • Temperature Shipping: Ambient
    • Sequence:
      MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYVVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GK EGYQDYEPEA
    • Source: Recombinant. A DNA sequence encoding the human Alpha-Synuclein 98AA sequence was expressed in E. coli
    • Purity: >95%
    • Molecular Mass: 10,020 Da theoretical

  • References
    1. Du, T., et al., (2019), Frontiers in Molecular Neuroscience, 12, 189
    2. Beyer, K., et al., (2008), Neurogenetics, 9 15-23
    3. 3. Röntgen, A., et al., (2024) Biophysics and Computational Biology, 121, 7

Related products