Publications

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Synuclein Citations

2017

Anna WilkaniecEmail authorMagdalena GąssowskaGrzegorz A. CzapskiMagdalena CieślikGrzegorz SulkowskiAgata Adamczyk (2017) P2X7 receptor-pannexin 1 interaction mediates extracellular alpha-synuclein-induced ATP release in neuroblastoma SH-SY5Y cells. Springer Link Purinergic Signalling; DOI: 10.1007/s11302-017-9567-2.
James C. Giffina, Robert C. Richardsb, Cheryl Craftc, Nusrat Jahanc, 1, Cindy Leggiadrob, Thierry Chopind, Michael Szemerdae, Shawna L. MacKinnonc, K.Vanya Ewart (2017) An extract of the marine alga Alaria esculenta modulates α-synuclein folding and amyloid formation. Science Direct Neuroscience; http://dx.doi.org/10.1016/j.neulet.2017.02.055.
J. Scott Miners, Seth Love (2017) Endothelin-converting enzymes degrade α-synuclein and are reduced in dementia with Lewy bodies. Journal of Neurochemistry; 10.1111/jnc.13974.
Kallunki, Pekka Fog, Karina,Vesterager, Louise Buur,Bergstrôm, Ann-louise, Sotty, Florence,Satijn, David, Van Den, Brink Edward, Parren, Paul,Rademaker, Rik,Vink, Tom,Malik, Ibrahim, John, Montezinho, Liliana Christina Pereira (2017) Agents, Uses and Methods for the Treatment of Synucleinopathy. Free Patents Online; doi: 10.1038/srep05797, doi: 10.1128/mBio.00345-10,DOI:10.1371.
J. Motyl,P. L. Wencel,M. Cieślik,R. P. Strosznajde, J. B. Strosznajder (2017) Alpha-synuclein alters differently gene expression of Sirts, PARPs and other stress response proteins: implications for neurodegenerative disorders. Springer Link Molecular Neurobiology; doi:10.1007/s12035-016-0317-1.
Cagla Sahin, Nikolai Lorenzen, Lasse Lemminger, Gunna Christiansen, Ian Max Møller, Louise Buur Vesterager, Lars Østergaard Pedersen, Karina Fog, Pekka Kallunki, Daniel E. Otzen (2017) Antibodies against the C-terminus of α-synuclein modulate its fibrillation. Science Direct Biophysical Chemistry Volume 220, January 2017, Pages 34–41; http://dx.doi.org/10.1016/j.bpc.2016.11.002.
Ismael Segura-Ulate, Barbara Yang, Javier Vargas-Medrano, Ruth G. Perez (2017) FTY720 (Fingolimod) reverses α-synuclein-Induced downregulation of brain-derived neurotrophic factor mRNA in OLN-93 oligodendroglial cells. Science Direct Neuropharmacology; http://dx.doi.org/10.1016/j.neuropharm.2017.01.028.

2016

Leire Almandoz-Gil, Veronica Lindström, Jessica Sigvardson,Philipp J. Kahle, Lars Lannfelt, Martin Ingelsson, Joakim Bergström (2016) Mapping of Surface-Exposed Epitopes of In Vitro and In Vivo Aggregated Species of Alpha-Synuclein. Springer Link Cellular and Molecular Neurobiology; doi:10.1007/s10571-016-0454-0.
Al-Hilaly, Youssra K and Biasetti, Luca and Blakeman, Ben J F and Pollack, Saskia J and Zibaee, Shahin and Abdul-Sada, Alaa and Thorpe, Julian R and Xue, Wei-Feng and Serpell, Louise C (2016) The involvement of dityrosine crosslinking in synuclein assembly and deposition in Lewy Bodies in Parkinson's disease.. Scientific Reports; http://doi.org/10.1038/srep39171.
William T. Hu (2016) DIAGNOSTIC TESTING IN DEMENTIA AND METHODS RELATED THERETO. Free Patents Online; Application Number: 14/417672.
Richard Gordon, Neeraj Singh, Vivek Lawana, Anamitra Ghosh, Dilshan S. Harischandra, Huajun Jin, Colleen Hogan, Souvarish Sarkar, Dharmin Rokad, Nikhil Panicker, Vellareddy Anantharam, Anumantha G. Kanthasamy, Arthi Kanthasamy (2016) Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease. Science Direct; doi:10.1016/j.nbd.2016.04.008.
Teng Ai, Daniel J. Wilson, Swati S. More, Jiashu Xie, and Liqiang Chen (2016) 5-((3-Amidobenzyl)oxy)nicotinamides as Sirtuin 2 Inhibitors. ACS Publications; DOI: 10.1021/acs.jmedchem.5b01376.
Yunden Jinsmaa, Patricia Sullivan, Yehonatan Sharabi, David S. Goldstein (2016) DOPAL is transmissible to and oligomerizes alpha-synuclein in human glial cells. Autonomic Neuroscience; DOI: http://dx.doi.org/10.1016/j.autneu.2015.12.008.

2015

Shijun Wang, Chun-Hsien Chu, Mingri Guo, Lulu Jiang, Hui Nie, Wei Zhang, Belinda Wilson, Li Yang, Tessandra Stewart, Jau-Shyong HongEmail author and Jing Zhang (2015) Identification of a specific α-synuclein peptide (α-Syn 29-40) capable of eliciting microglial superoxide production to damage dopaminergic neurons. BioMed Central; DOI: 10.1186/s12974-016-0606-7.
Tatiana K Rostovtseva, Philip A Gurnev, Olga Protchenko, David P Hoogerheide Thai Leong Yap, Caroline C Philpott, Jennifer C Lee, Sergey M Bezrukov (2015) α-Synuclein Shows High-Affinity Interaction with Voltage-Dependent Anion Channel Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease. Research Gate; DOI: 10.1074/jbc.M115.641746.
Tomasz Brudek, Kristian Winge, Nadja Bredo Rasmussen, Justyna Maria Bahl Czarna, Julia Tanassi, Tina Klitmøller Agander, Thomas M. Hyde, and Bente Pakkenberg (2015) Altered Alpha-Synuclein, Parkin, and Synphilin Isoform Levels in Multiple System Atrophy Brains. Wiley Online Library; DOI: 10.1111/jnc.13392.
Aaron D. Thome, David G. Standaert, Ashley S. Harms (2015) Fractalkine Signaling Regulates the Inflammatory Response in an α-Synuclein Model of Parkinson Disease. PLOS One; DOI: 10.1371/journal.pone.0140566.
Sandeep K. Sharma, Erik Chorell, Pernilla Wittung-Stafshede (2015) Insulin-degrading enzyme is activated by the C-terminus of α-synuclein. Science Direct; doi:10.1016/j.bbrc.2015.09.002.
Joe Kakish, Dongsoo Lee, and Jeremy Stuart Lee (2015) Drugs which bind to alpha-synuclein. Neuroprotective or neurotoxic?. ACS Chemical; DOI: 10.1021/acschemneuro.5b00172.
Mari Suzuki, Nobuhiro Fujikake, Toshihide Takeuchi, Ayako Kohyama-Koganeya, Kazuki Nakajima, Yoshio Hirabayashi, Keiji Wada and Yoshitaka Nagai (2015) Glucocerebrosidase deficiency accelerates the accumulation of proteinase K-resistant α-synuclein and aggravates neurodegeneration in a Drosophila model of Parkinson's disease. Oxford Journals; doi: 10.1093/hmg/ddv372.
Sandeep K. Sharma, Erik Chorell, Pernilla Wittung-Stafshede (2015) Insulin-degrading enzyme is activated by the C-terminus of α-synuclein. ScienceDirect; doi:10.1016/j.bbrc.2015.09.002.
Iban Aldecoa, Judith Navarro-Otano, Nadia Stefanova, Fabienne S. Sprenger, Klaus Seppi, Werner Poewe, Miriam Cuatrecasas, Francesc Valldeoriolab, c, Ellen Gelpif, Eduard Tolosa (2015) Alpha-synuclein immunoreactivity patterns in the enteric nervous system. ScienceDirect; doi:10.1016/j.neulet.2015.07.005.
Andrew F. Fischer, Kathryn Mansfield Matera (2015) Stabilization of Alpha-Synuclein Oligomers In Vitro by the Neurotransmitters, Dopamine and Norepinephrine: The Effect of Oxidized Catecholamines. Springer Link; DOI: 10.1007/s11064-015-1597-y.
Tatiana K. Rostovtseva, Philip A. Gurnev, Olga Protchenko, David P. Hoogerheide, Thai Leong Yap, Caroline C. Philpott, Jennifer C. Lee, and Sergey M. Bezrukov (2015) Alpha Synuclein Shows High-Affinity Interaction with Voltage-Dependent Anion Channel Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease. JBC Papers in Press; doi:10.1074/jbc.M115.641746.
Staffan Holmqvista, Marinka Brouwer, Mehdi Djelloul, Alejandro Garcia Diaz, Michael J. Devine, Anna Hammarbergf, Karina Fog, Tilo Kunath, Laurent Roybon (2015) Generation of human pluripotent stem cell reporter lines for the isolation of and reporting on astrocytes generated from ventral midbrain and ventral spinal cord neural progenitors. ScienceDirect; doi:10.1016/j.scr.2015.05.014.
Ryoichi Takahashi, Kenjiro Ono, Yusaku Takamura, Mineyuki Mizuguchi, Tokuhei Ikeda, Hisao Nishijo andMasahito Yamada (2015) Phenolic compounds prevent the oligomerization of α-synuclein and reduce synaptic toxicity. JNC Journal of Neurochemistry; DOI: 10.1111/jnc.13180.
Tatiana K. Rostovtseva, Philip A. Gurnev, Olga Protchenko, David P. Hoogerheide, Thai Leong Yap, Caroline C. Philpott, Jennifer C. Lee and Sergey M. Bezrukov (2015) α-Synuclein Shows High Affinity Interaction with Voltage-dependent Anion Channel, Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease. The Journal of Biological Chemistry; doi: 10.1074/jbc.M115.641746.
Andrew F. Fischer, Kathryn Mansfield Matera (2015) Stabilization of Alpha-Synuclein Oligomers In Vitro by the Neurotransmitters, Dopamine and Norepinephrine: The Effect of Oxidized Catecholamines. Springer Link; DOI 10.1007/s11064-015-1597-y.

2014

S.N. Pchelina, E.P. Nuzhnyib, A.K. Emelyanov,T.M. Boukina, T.S. Usenko, M.A. Nikolaev, G.N. Salogub, A.F. Yakimovskii, E.Yu. Zakharova (2014) Increased plasma oligomeric alpha-synuclein in patients with lysosomal storage diseases. Science Direct; doi:10.1016/j.neulet.2014.09.041.
Miroslav Radman, Anita Krisko (2014) Protein Damage in Aging and Age-Related Diseases. FPO; United States Patent Application 20140235735.
John F. Kellie, Richard E. Higgs, John W. Ryder, Anthony Major, Thomas G. Beach, Charles H. Adler, Kalpana Merchant, & Michael D. Knierman (2014) Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry. Scientific Reports; doi:10.1038/srep05797.
Omid Tavassoly, Joe Kakish, Sergiy Nokhrin, Oleg Dmitriev, Jeremy S. Lee (2014) The use of nanopore analysis for discovering drugs which bind to α-synuclein for treatment of Parkinson's disease. Science Direct; DOI: 10.1016/j.ejmech.2014.07.090.
Gyan Modi, Chandrashekhar Voshavar, Sanjib Gogoi, Mrudang Shah, Tamara Antonio, Maarten E. A. Reith, and Aloke K. Dutta (2014) Multifunctional D2/D3 Agonist D-520 with High in Vivo Efficacy: Modulator of Toxicity of Alpha-Synuclein Aggregates. ACS Publications; DOI: 10.1021/cn500084x.
Guoxiang Liu, Jia Yu, Jinhui Ding, Chengsong Xie, Lixin Sun, Iakov Rudenko, Wang Zheng, Namratha Sastry, Jing Luo, Gay Rudow, Juan C. Troncoso, and Huaibin Cai (2014) Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation. JCI: The Journal of Clinical Investigation; doi:10.1172/JCI72176..
Omid Tavassoly, Sergiy Nokhrin, Oleg Y. Dmitriev, and Jeremy S. Lee (2014) Cu(II) and dopamine bind to α-Synuclein and cause large conformational changes. FEBS Journal; DOI: 10.1111/febs.12817 (Pay to View).
Magdalena Gąssowska, Grzegorz A. Czapski, Beata Pająk, Magdalena Cieślik, Anna M. Lenkiewicz, Agata Adamczyk (2014) Extracellular α-Synuclein Leads to Microtubule Destabilization via GSK-3β-Dependent Tau Phosphorylation in PC12 Cells. PLOS One; DOI: 10.1371/journal.pone.0094259.
Methodios Ximerakis, Georgios Pampalakis, Theodoros I. Roumeliotis, Vasia-Samantha Sykioti, Spiros D. Garbis, Leonidas Stefanis, Georgia Sotiropoulou, and Kostas Vekrellis (2014) Resistance of naturally secreted -synuclein to proteolysis. FEBS Journal; doi: 10.1096/fj.13-245852.
Walter Maetzler, Anja Apel, Markus Langkamp, Christian Deuschle, Sarah Selina Dilger, Johannes Georg Stirnkorb, Claudia Schulte, Erwin Schleicher, Thomas Gasser, Daniela Berg (2014) Comparable Autoantibody Serum Levels against Amyloid- and Inflammation-Associated Proteins in Parkinson’s Disease Patients and Controls. PLoS ONE; DOI: 10.1371/journal.pone.0088604.
Srabasti Acharya, Brian M. Safaie, Piriya Wongkongkathep, Magdalena I. Ivanova, Aida Attar, Frank-Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Gal Bitan, and Lisa J. Lapidus (2014) Molecular Basis for Preventing α-Synuclein Aggregation by a Molecular Tweezer. The Journal of Biological Chemistry; doi: 10.1074/jbc.M113.524520.
Markus Mandler, Elvira Valera, Edward Rockenstein, Harald Weninger, Christina Patrick, Anthony Adame, Radmila Santic, Stefanie Meindl, Benjamin Vigl, Oskar Smrzka, Achim Schneeberger, Frank Mattner, Eliezer Masliah (2014) Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials. DOI 10.1007/s00401-014-1256-4; Title Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials Print ISSN 0001-6322 Online ISSN 1432-0533 Publisher Springer Berlin Heidelberg.
Scott Miners, Hayley Moulding, Rohan de Silva, Seth Love (2014) Reduced vascular endothelial growth factor and capillary density in the occipital cortex in dementia with Lewy bodies. DOI: 10.1111/bpa.12130; Accepted manuscript online: 13 FEB 2014 01:41AM EST Manuscript Accepted: 2 FEB 2014.

2013

Rudy Orlando Cedillos (2013) Alpha-Synuclein Aggregates Activate the Nlrp3Inflammasome Following Vesicle Rupture. Loyola eCommons; (2013). Master's Theses. Paper 1859.
Anahit Ghochikyan, Irina Petrushina, Hayk Davtyan, Armine Hovakimyan, Tommy Saing, Arpine Davtyan, David H. Cribbs, Michael G. Agadjanyan (2013) Immunogenicity of epitope vaccines targeting different B cell antigenic determinants of human α-synuclein: Feasibility study. Science Direct; doi:10.1016/j.neulet.2013.12.028.
Ruben Berrocal, Padmaraju Vasudevaraju, Shantinath Satappa Indi, Krothapalli Raja Surya Sambasiva Rao, and K.S. Rao (2013) In vitro Evidence that an Aqueous Extract of Centella asiatica Modulates α-Synuclein Aggregation Dynamics. IOS Press; DOI: 10.3233/JAD-131187 (Pay to View).
Grzegorz A. Czapski, Magdalena Gąssowska, Anna Wilkaniec, Magdalena Cieślik, and Agata Adamczyk (2013) Extracellular alpha-synuclein induces calpain-dependent overactivation of cyclin-dependent kinase 5 in vitro. Elsevier B.V.; http://dx.doi.org/10.1016/j.febslet.2013.07.053 (Pay to view).
David Freeman, Rudy Cedillos, Samantha Choyke, Zana Lukic, Kathleen McGuire, Shauna Marvin, Andrew M. Burrage, Stacey Sudholt, Ajay Rana, Christopher O'Connor, Christopher M. Wiethoff, Edward M. Campbell (2013) Alpha-Synuclein Induces Lysosomal Rupture and Cathepsin Dependent Reactive Oxygen Species Following Endocytosis. PLOS One; DOI: 10.1371/journal.pone.0062143.
Douglas G. Walker, Lue LF, Adler CH, Shill HA, Caviness JN, Sabbagh MN, Akiyama H, Serrano GE, Sue LI, Beach TG (2013) Changes in Properties of Serine 129 Phosphorylated α-Synuclein with Progression of Lewy Type Histopathology in Human Brains. Experimental Neurology; Volume 240, February 2013, Pages 190–204; doi 10.1016/j.expneurol.2012.11.020.
Wright, O., Zhang, L., Liu, Y., Yoshimi, T., Zheng, Y. and Tunnacliffe, A. (2013) Critique of the use of fluorescence-based reporters in Escherichia coli as a screening tool for the identification of peptide inhibitors of Aβ42 aggregation. J. Peptide Sci; doi: 10.1002/psc.2474 (Pay to View).
TL Yap, A Velayati, E Sidransky, JC Lee (2013) Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity.. Molecular Genetics and Metabolism; 2013 Jan;108(1):56-64, ISSN 1096-7192, DOI 10.1016/j.ymgme.2012.11.010.

2012

Smith LM, Klaver AC, Coffey MP, Dang L, Loeffler DA. (2012) Effects of intravenous immunoglobulin on alpha synuclein aggregation and neurotoxicity. Int Immunopharmacol; 2012 Sep 28. pii: S1567-5769(12)00270-6. doi: 10.1016/j.intimp.2012.09.007..
Maetzler W, Langkamp M, Lerche S, Godau J, Brockmann K, Gaenslen A, Huber H, Wurster I, Niebler R, Eschweiler GW, Berg D. (2012) Lowered Serum Amyloid-β1-42 Autoantibodies in Individuals with Lifetime Depression. Journal of Alzheimer's Disease; 2012 Jul 5. [Epub ahead of print] DOI: 10.3233/JAD-2012-120625.
Tavassoly, O., Lee, J.S. (2012) Methamphetamine binds to α-synuclein and causes a conformational change which can be detected by nanopore analysis. FEBS Letters; In Press, Uncorrected proof (5 July 2012), doi:10.1016/j.febslet.2012.06.040.
Mandler, M., Weninger, H., Santic, R., Lahsnig, C. (2012) Means for Treating Synucleinopathies. United States Patent Application 20120156234; 2012 United States AFFIRIS AG (Vienna, AT) 20120156234.
Prabhudesai, S., Sinha, S., Attar, A., Kotagiri, A., Fitzmaurice, AG, Lakshmanan, R., Ivanova, MI, Loo, JA, Klärner, FG and Schrader, T., et al. (2012) A Novel “Molecular Tweezer” Inhibitor of α-Synuclein Neurotoxicity in Vitro and in Vivo. Neurotherapeutics; Volume 9, Number 2 (2012), 464-476, DOI: 10.1007/s13311-012-0105-1.
Vasudevaraju, P., Guerrero, E., Hegde, ML, Collen, TB, Britton, GB, and Rao, KS (2012) New evidence on α-synuclein and Tau binding to conformation and sequence specific GC* rich DNA: Relevance to neurological disorders. J Pharm Bioallied Sci.; 2012 Apr-Jun; 4(2): 112–117. doi: 10.4103/0975-7406.9481; PMCID: PMC3341714.
Kovacs, GG, Wagner, U., Dumont, B., Pikkarainen, M., Osman, AA, Streichenberger, N., Leisser, I., Verchère, J., Baron, T. and Alafuzoff, I., et al. (2012) An antibody with high reactivity for disease-associated α-synuclein reveals extensive brain pathology. Acta Neuropathologica; 2012, DOI: 10.1007/s00401-012-0964-x.
Martin, Z. S., Neugebauer, V., Dineley, K. T., Kayed, R., Zhang, W., Reese, L. C. and Taglialatela, G., (2012) α-Synuclein oligomers oppose long-term potentiation and impair memory through a calcineurin-dependent mechanism: relevance to human synucleopathic diseases.. Journal of Neurochemistry; 120: 440–452. 2012 Feb; doi: 10.1111/j.1471-4159.2011.07576.x.
Tousi, A.S., Buck, D.J., Curtis, T., Davis, R.L. (2012) α-Synuclein potentiates interleukin-1β-induced CXCL10 expression in human A172 astrocytoma cells. Neuroscience Letters; Volume 507, Issue 2, 24 January 2012, Pages 133–136 DOI /10.1016/j.neulet.2011.12.001.

2011

Weihofen, A., Grimm, J. , Nitsch, R. , Hock, C. (2011) Human Anti-Alpha-Synuclein Antibodies. United States Patent Application; United States Patent Application 20110300077; 2011 Dec 8; DOI: y2011/0300077.html..
Couch, Y, Alvarez-Erviti, L., Sibson, NR, Wood, M and Anthony, D. (2011) The acute inflammatory response to intranigral a-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation. Journal of Neuroinflammation; 2011, 8:166.
Fantini, J., Carlus, D., Yahi, N. (2011) The fusogenic tilted peptide (67–78) of α-synuclein is a cholesterol binding domain. Biochimica et Biophysica Acta (BBA) – Biomembranes; Volume 1808, Issue 10, 2011 October, Pages 2343–2351.
Dodel, R., Bacher, M., Besong Agbo, D., Hagemann, S., Balzer-geldsetzer, M. (2011) Naturally occuring autoantibodies against alpha-synuclein that inhibit the aggregation and cytotoxicity of alpha-synuclein. European Patent Application; European Patent Application EP2366714; 2011 Sept. 21.
Coffey C, Shaw L, Trojanowski J (2011) PPMI Parkinson’s Progression Monitoring Initiative : CSF α-synuclein interlaboratory study. Parkinson ‘s Progession Markers Initiative; 2011 July 7 PPMI – SYN – RR-1.
Verhaara, R., Jongenelena, CA,, Gerardb, M., Baekelandt, V., Van Dama, A., Wilhelmusa, MM., Drukarcha, B. (2011) Blockade of enzyme activity inhibits tissue transglutaminase-mediated transamidation of α-synuclein in a cellular model of Parkinson's disease. Neurochemistry International; Volume 58, Issue 7, June 2011, Pages 785–793 DOI: 10.1016/j.neuint.2011.03.004.
Milowska, K., ,Malachowska, M., Gabryelak, T. (2011) PAMAM G4 dendrimers affect the aggregation of α-synuclein. International Journal of Biological Macromolecules; Volume 48, Issue 5, 2011 June 1, Pages 742–746; DOI: 10.1016/j.ijbiomac.2011.02.021..
Fantini, J., Yahi, N. (2011) Molecular Basis for the Glycosphingolipid-Binding Specificity of α-Synuclein: Key Role of Tyrosine 39 in Membrane Insertion. Journal of Molecular Biology; Volume 408, Issue 4, 13 May 2011, Pages 654–669; DOI: 10.1016/j.bbr.2011.03.031.
Choi DH, Kim YJ, Kim YG, Joh TH, Beal MF, Kim YS. (2011) Role of Matrix Metalloproteinase 3-mediated α-Synuclein Cleavage in Dopaminergic Cell Death. J Biol Chem.; 2011 Apr 22;286(16):14168-77. Epub 2011 Feb 17..
Beales, PA, Bergstrom, CL, Geerts, N., Groves, JT, and Vanderlick, K. (2011) Single Vesicle Observations of the Cardiolipin−Cytochrome c Interaction: Induction of Membrane Morphology Changes. Langmuir; 2011 April 19, 27 (10), pp 6107–6115 DOI: 10.1021/la104924c.
Kalia LV, Kalia SK, Chau H, Lozano AM, Hyman BT, et al. (2011) Ubiquitinylation of α-Synuclein by Carboxyl Terminus Hsp70-Interacting Protein (CHIP) Is Regulated by Bcl-2-Associated Athanogene 5 (BAG5). PLoS ONE; 6(2): e14695. 2011 Feb 16; doi:10.1371/journal.pone.0014695.
Gordon R, Hogan CE, Neal ML, Anantharam V, Kanthasamy AG, Kanthasamy A. (2011) A simple magnetic separation method for high-yield isolation of pure primary microglia. J Neurosci Methods; 2011 Jan 15; 194 (2) :287-96. PubMed PMID:21074565..

2010

Mata IF, Shi M, Agarwal P, Chung KA, Edwards KL, Factor SA, Galasko DR, Ginghina C, Griffith A, Higgins DS, Kay DM, Kim H, Leverenz JB, Quinn JF, Roberts JW, Samii A, Snapinn KW, Tsuang DW, Yearout D, Zhang J, Payami H, Zabetian CP. (2010) SNCA variant associated with Parkinson disease and plasma alpha-synuclein level. Arch Neurol; 2010 Nov; 67 (11) :1350-6. PubMed PMID:21060011; PubMed Central PMCID: PMC3010848..
Dragusanu M, Petre BA, Slamnoiu S, Vlad C, Tu T, Przybylski M. (2010) On-line bioaffinity-electrospray mass spectrometry for simultaneous detection, identification, and quantification of protein-ligand interactions. J Am Soc Mass Spectrom; 2010 Oct; 21 (10) :1643-8. PubMed PMID:20692851..
Dragusanu, M., Petre, B.A., Slamnoiu, S., Vlad, C., Tu, T., Przybylski, M. (2010) On-Line Bioaffinity-Electrospray Mass Spectrometry for Simultaneous Detection, Identification, and Quantification of Protein–Ligand Interactions. Journal of the American Society for Mass Spectrometry; Volume 21, Issue 10, October 2010, Pages 1643–1648 doi 10.1016/j.jasms.2010.06.011.
Mougenot AL, Bétemps D, Hogeveen KN, Kovacs GG, Chouaf-Lakhdar L, Milhavet O, Lehmann S, Legastelois S, Pin JJ, Baron TG. (2010) Production of a monoclonal antibody, against human α-synuclein, in a subpopulation of C57BL/6J mice, presenting a deletion of the α-synuclein locus. J Neurosci Methods; 2010 Oct 15; 192 (2) :268-76. PubMed PMID:20709102..
Patrias L. M., Klaver A. C., Coffey M.P., Loeffler D.A. (2010) Specific antibodies to soluble alpha-synuclein conformations in intravenous immunoglobulin preparations. Clinical & Experimental Immunology; Volume 161, Issue 3, pages 527–535, September 2010 DOI: 10.1111/j.1365-2249.2010.04214.x.
Lee EJ, Woo MS, Moon PG, Baek MC, Choi IY, Kim WK, Junn E, Kim HS. (2010) Alpha-synuclein activates microglia by inducing the expressions of matrix metalloproteinases and the subsequent activation of protease-activated receptor-1. J Immunol; 2010 Jul 1; 185 (1) :615-23. PubMed PMID:20511551..
Liu J, Shi M, Hong Z, Zhang J, Bradner J, Quinn T, Beyer RP, Mcgeer PL, Chen S, Zhang J. (2010) Identification of ciliary neurotrophic factor receptor alpha as a mediator of neurotoxicity induced by alpha-synuclein. Proteomics; 2010 Jun; 10 (11) :2138-50. PubMed PMID:20340160; PubMed Central PMCID: PMC3013276..
Hong, Z., Shi, M., Chung, K.A., Quinn, J.F., Peskind, E.R., Galasko, D., Jankovic, J., Zabetian, C.P., Leverenz, J.B., Baird, G., Montine, T.J., Hancock, A.M., Hwang, H., Pan, C., Bradner, J., Kang, U.J., Jensen, P.H., Zhang, J. (2010) DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease. Brain; 133 (3): 713-726. doi: 10.1093/brain/awq008.

2009

Adamczyk A, Czapski GA, Ka?mierczak A, Strosznajder JB. (2009) Effect of N-methyl-D-aspartate (NMDA) receptor antagonists on alpha-synuclein-evoked neuronal nitric oxide synthase activation in the rat brain. Pharmacol Rep; 2009 Nov-Dec;61(6):1078-85. PubMed PMID: 20081243..
Parihar MS, Parihar A, Fujita M, Hashimoto M, Ghafourifar P. (2009) Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells. Int J Biochem Cell Biol; 2009 Oct;41(10):2015-24. Epub 2009 May 19. PubMed PMID: 19460457..
Zuo P, Qu W, Cooper RN, Goyer RA, Diwan BA, Waalkes MP. (2009) Potential role of alpha-synuclein and metallothionein in lead-induced inclusion body formation. Toxicol Sci; 2009 Sep;111(1):100-8. Epub 2009 Jun 19. PubMed PMID: 19542206; PubMed Central PMCID: PMC2726298..
Chanthamontri C, Liu J, McLuckey SA. (2009) Charge State Dependent Fragmentation of Gaseous alpha-Synuclein Cations via Ion Trap and Beam-Type Collisional Activation. Int J Mass Spectrom; 2009 Jun 1;283(1-3):9-16. PubMed PMID: 20160958; PubMed Central PMCID: PMC2759116..
Adamczyk A, Ka?mierczak A. (2009) Alpha-synuclein inhibits poly (ADP-ribose) polymerase-1 (PARP-1) activity via NO-dependent pathway.. Folia Neuropathol; 2009;47(3):247-51. PubMed PMID: 19813144..
Yin S, Loo JA. (2009) Mass spectrometry detection and characterization of noncovalent protein complexes. Methods Mol Biol; 2009;492:273-82. PubMed PMID: 19241039..
Näsström T, Wahlberg T, Karlsson M, Nikolajeff F, Lannfelt L, Ingelsson M, Bergström J. (2009) The lipid peroxidation metabolite 4-oxo-2-nonenal cross-links alpha-synuclein causing rapid formation of stable oligomers. Biochem Biophys Res Commun; 2009 Jan 23;378(4):872-6. Epub 2008 Dec 12. PubMed PMID: 19070597..
Näsström, T., Wahlberg, T., Karlsson, M., Nikolajeff, F., Lannfelt, L., Ingelsson, M., Bergström, J. (2009) The lipid peroxidation metabolite 4-oxo-2-nonenal cross-links α-synuclein causing rapid formation of stable oligomers. Biochemical and Biophysical Research Communications; 378 (4): 872-876.

2008

Lya, T., Julian, R.R. (2008) Protein–Metal Interactions of Calmodulin and α-Synuclein Monitored by Selective Noncovalent Adduct Protein Probing Mass Spectrometry. Journal of the American Society for Mass Spectrometry; 19(11): 1663-1672..
Grabenauer, M., Bernstein, SL., Lee, JC., Wyttenbach, T., Dupuis, NF., Gary, HB., Winker, JR., Bowers, MT. (2008) Spermine Binding to Parkinson’s Protein α-Synuclein and Its Disease-related A30P and A53T Mutants. The Journal of Physical Chemistry B; 112 (35), pp 11147-11154. DOI abs/10.1021/jp801175w.
Madine, J., Hughes, E., Doig, AJ., Middleton, DA. (2008) The effect of α-synuclein on phospholipid vesicle integrity: a study using 31P NMR and electron mircroscopy. Moleculalr Membrane Biology; Vol. 25, No.6-7, Pages 518-527 DOI abs/10.1080/09687680802467977.
Li, Z.N., Lee, B.J., Langley, W.A., Bradley, K.C., Russell, R.J., Steinhauer, D.A. (2008) Length Requirements for Membrane Fusion of Influenza Virus Hemagglutinin Peptide Linkers to Transmembrane or Fusion Peptide Domains {triangledown}. Journal of Virology; 82(13): 6337-6348..
Madine, J., Doig, AJ., Middleton, DA. (2008) Design of an N-Methylated Peptide Inhibitor of α-Synuclein Aggregation Guided by Solid-State NMR. Journal of the American Chemical Society; 130 (25), pp 7873-7881 DOI abs/10.1021.ja075356q.
Jacobsa, A., Garga, H., Viarda, M., Raviva, Y., Puria, A., Blumenthala, R. (2008) HIV-1 envelope glycoprotein-mediated fusion and pathogenesis: Implications for therapy and vaccine developmentstar. Vaccine; 26(24): 3026-3035..
Kasai, T., Tokuda, T., Yamaguchi, N., Watanabe, Y., Kametani, F., Nakagawa, M., Mizuno, T. (2008) Cleavage of normal and pathological forms of α-synuclein by neurosin in vitro. Neuroscience Letters; 436, 52-56.
Parihar, M.S., Parihar, A.,Fujita, M., Hashimoto, M., Ghafourifar, P. (2008) Mitochondrial association of alpha-synuclein causes oxidative stress. Journal of the Cellular and Molecular Life Sciences; 65(7-8): 1272-1284..
Wieneke J.A., Abdo, W.F., Melis, R., Williams, S., Bloem, B.R., Verbeek, M.M. (2008) A more efficient enzyme-linked immunosorbent assay for measurement of α-synuclein in cerebrospinal fluid. Journal of Neuroscience Methods; 168(1): 182-185..
Thoennesa, S., Lia, Z.N., Leea, B.J., Langleya, W.A., Skehelb, J.J., Russellc, R.J., Steinhauera, D.A. (2008) Analysis of residues near the fusion peptide in the influenza hemagglutinin structure for roles in triggering membrane fusion. Virology; 370(2): 403-414..
Ghosha, J.G., Houcka, S.A., Clarka, J.I. (2008) Interactive sequences in the molecular chaperone, human αB crystallin modulate the fibrillation of amyloidogenic proteins. The International Journal of Biochemistry & Cell Biology; 40(5): 954-967..
Wathen, B., Jia, Z. (2008) Local and Nonlocal Environments around Cis Peptides. J. Proteome Res; 7(01): 145-153..
Williamson, S.J.M (2008) Non-toxic concentrations of a-synuclein exacerbate Parkinson’s disease-like cell death by inducing mitochondrial dysfunction. The Universtiy of Edinburgh; 2008.
Leaman, Douglas W. (2008) Recent progress in oligonucleotide therapeutics: antisense to aptamers. Expert Opinion on Drug Discovery; 3(9): 997-1009..