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Synuclein Citations


John D. Graef, Nina Hoque, Craig Polson, Ling Yang, Lawrence Iben, Yang Cao, Nino Devidze, Michael K. Ahlijanian, Jere E. Meredith Jr. (2019) Characterization of pathology-inducing α-synuclein species from human diseased brain tissue. bioRxiv; doi:
Di Hu, Xiaoyan Sun, Xudong Liao, Xinwen Zhang, Sara Zarabi,..Xin Qi (2019) Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity. Springer Berlin Heidelberg;
Eric S. Luth, Irina G. Stavrovskaya (2019) Measuring Mitochondrial Dysfunction Caused by Soluble α-Synuclein Oligomers. Humana Press, New York, NY;
Anna Wilkaniec, Anna M. Lenkiewicz, Grzegorz A. Czapski, Henryk M. Jęśko, Wojciech Hilgier, Robert Brodzik, Magdalena Gąssowska-Dobrowolska, Carsten Culmsee, Agata Adamczyk (2019) Extracellular Alpha-Synuclein Oligomers Induce Parkin S-Nitrosylation: Relevance to Sporadic Parkinson’s Disease Etiopathology. Springer;
Susan M.L. Banks, Audrey T. Medeiros, Molly McQuillan, David J. Busch, Ana Sofia Ibarraran-Viniegra, Subhojit Roy, Rui Sousa, Eileen M. Lafer, Jennifer R. Morgan (2019) Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess α-Synuclein at Synapses. Journal of Neuroscience;


Andreas Weihofen, YuTing Liu, Joseph W. Arndt, Christian Huy, Chao Quan, Benjamin A. Smith, Jean-Luc Baeriswyl, Nicole Cavegn, Luzia Senn, Lihe Su, Galina Marsh, Pavan Auluck, Fabio Montrasio, Roger M. Nitsch, Warren D. Hirst, Jesse M. Cedarbaum, R. Blake Pepinsky, Jan Grimm, Paul H. Weinreb (2018) Development of an aggregate-selective, human-derived α-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models.;
Ross S. Mancini, Yanfei Wang, and Donald F. Weaver (2018) Phenylindanes in Brewed Coffee Inhibit Amyloid-Beta and Tau Aggregation. Frontiers;
Alexandra Albus, Maike Gold, Jan-Philipp Bach, Monika Burg-Roderfeld, Marit Jördens, Yvonne Kirchhein, Yannick Kronimus, David Mengel, Inga Zerr, Richard Dodel (2018) Extending the functional characteristics of naturally occurring autoantibodies against β-Amyloid, Prion Protein and α-Synuclein. PLOS ONE;
Anna Wilkaniec, Anna M. Lenkiewicz, Grzegorz A. Czapski, Henryk M. Jęśko, Wojciech Hilgier, Robert Brodzik, Magdalena Gąssowska-Dobrowolska, Carsten Culmsee, Agata Adamczyk (2018) Extracellular Alpha-Synuclein Oligomers Induce Parkin S-Nitrosylation: Relevance to Sporadic Parkinson’s Disease Etiopathology.; 10.1007/s12035-018-1082-0.
Liyan Hou, Xiuqi Bao, Caixia Zang, Hanyu Yang, Fuqiang Sun, Yuning Che, Xuefei Wu, Shao Li, Dan Zhang, Qingshan Wang (2018) Integrin CD11b mediates α-synuclein-induced activation of NADPH oxidase through a Rho-dependent pathway. Science Direct;
Motyl, J., Wencel, P.L., Cieślik, M. Strosznajder,R.P., Strosznajder,J.B. (2018) Alpha-synuclein alters differently gene expression of Sirts, PARPs and other stress response proteins: implications for neurodegenerative disorders..;
Rebecca Ann Chmielowski (2018) DESIGN OF ANTIOXIDANT NANOTHERAPEUTICS FOR ATTENUATION OF ATHEROGENESIS AND NEUROINFLAMMATION. School of Graduate Studies Electronic Theses and Dissertations;


Goldman, J.G., Andrews, H., Amara, A., Naito, A., Alcalay, R.N.,…Kang, U.K. (2017) Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features..;
Patrick Oeckl, Petra Steinacker, and Markus Otto (2017) Comparison of Internal Standard Approaches for SRM Analysis of Alpha-Synuclein in Cerebrospinal Fluid.; 10.1021/acs.jproteome.7b00660.
Hiroyuki Watanabe, Taisuke Ariyoshi, Akihiko Ozaki, Masafumi Ihara, Masahiro Ono, Hideo Saji (2017) Synthesis and biological evaluation of novel radioiodinated benzimidazole derivatives for imaging α-synuclein aggregates.;
Junichi Matsumoto, Tessandra Stewart, Lifu Sheng, Na Li, Kristin Bullock, Ning Song, Min Shi, William A Banks, Jing ZhangEmail (2017) Transmission of α-synuclein-containing erythrocyte-derived extracellular vesicles across the blood-brain barrier via adsorptive mediated transcytosis: another mechanism for initiation and progression of Parkinson’s disease?.; 10.1186/s40478-017-0470-4.
James Scott Miners; Seth Love (2017) Endothelin‐converting enzymes degrade α‐synuclein and are reduced in dementia with Lewy bodies. Online Library;
Tomasz Brudek, Kristian Winge, Jonas Folke, Søren Christensen, Karina Fog, Bente Pakkenberg and Lars Østergaard Pedersen (2017) Autoimmune antibody decline in Parkinson’s disease and Multiple System Atrophy; a step towards immunotherapeutic strategies. BioMedCentral;
Anna Wilkaniec, Magdalena Gąssowska, Grzegorz A. Czapski, Magdalena Cieślik, Grzegorz Sulkowski, Agata Adamczyk (2017) P2X7 receptor-pannexin 1 interaction mediates extracellular alpha-synuclein-induced ATP release in neuroblastoma SH-SY5Y cells. Springer Link Purinergic Signalling; DOI: 10.1007/s11302-017-9567-2.
James C. Giffina, Robert C. Richardsb, Cheryl Craftc, Nusrat Jahanc, 1, Cindy Leggiadrob, Thierry Chopind, Michael Szemerdae, Shawna L. MacKinnonc, K.Vanya Ewart (2017) An extract of the marine alga Alaria esculenta modulates -synuclein folding and amyloid formation. Elsevier;
Cagla Sahin, Nikolai Lorenzen, Lasse Lemminger, Gunna Christiansen, Ian Max Møller, Louise Buur Vesterager, Lars Østergaard Pedersen, Karina Fog, Pekka Kallunki, Daniel E. Otzen (2017) Antibodies against the C-terminus of α-synuclein modulate its fibrillation. Science Direct Biophysical Chemistry Volume 220, January 2017, Pages 34–41;
Yunden Jinsmaa, Patricia Sullivan, Yehonatan Sharabi, David S. Goldstein (2017) DOPAL is transmissible to and oligomerizes alpha-synuclein in human glial cells.. NCBI; doi: 10.1016/j.autneu.2015.12.008.
Ismael Segura-Ulate, Barbara Yang, Javier Vargas-Medrano, Ruth G. Perez (2017) FTY720 (Fingolimod) reverses α-synuclein-Induced downregulation of brain-derived neurotrophic factor mRNA in OLN-93 oligodendroglial cells. Science Direct Neuropharmacology;


Leire Almandoz-Gil, Veronica Lindström, Jessica Sigvardson,Philipp J. Kahle, Lars Lannfelt, Martin Ingelsson, Joakim Bergström (2016) Mapping of Surface-Exposed Epitopes of In Vitro and In Vivo Aggregated Species of Alpha-Synuclein. Springer Link Cellular and Molecular Neurobiology; doi:10.1007/s10571-016-0454-0.
Al-Hilaly, Youssra K and Biasetti, Luca and Blakeman, Ben J F and Pollack, Saskia J and Zibaee, Shahin and Abdul-Sada, Alaa and Thorpe, Julian R and Xue, Wei-Feng and Serpell, Louise C (2016) The involvement of dityrosine crosslinking in synuclein assembly and deposition in Lewy Bodies in Parkinson's disease.. Scientific Reports;
Richard Gordon, Neeraj Singh, Vivek Lawana, Anamitra Ghosh, Dilshan S. Harischandra, Huajun Jin, Colleen Hogan, Souvarish Sarkar, Dharmin Rokad, Nikhil Panicker, Vellareddy Anantharam, Anumantha G. Kanthasamy, Arthi Kanthasamy (2016) Protein Kinase Cδ Upregulation in Microglia Drives Neuroinflammatory Responses and Dopaminergic Neurodegeneration in Experimental Models of Parkinson's Disease. NCBI; doi: 10.1016/j.nbd.2016.04.008.
Teng Ai, Daniel J. Wilson, Swati S. More, Jiashu Xie, and Liqiang Chen (2016) 5-((3-Amidobenzyl)oxy)nicotinamides as Sirtuin 2 Inhibitors. ACS Publications; DOI: 10.1021/acs.jmedchem.5b01376.
Yunden Jinsmaa, Patricia Sullivan, Yehonatan Sharabi, David S. Goldstein (2016) DOPAL is transmissible to and oligomerizes alpha-synuclein in human glial cells. Autonomic Neuroscience; DOI:


Shijun Wang, Chun-Hsien Chu, Mingri Guo, Lulu Jiang, Hui Nie, Wei Zhang, Belinda Wilson, Li Yang, Tessandra Stewart, Jau-Shyong HongEmail author and Jing Zhang (2015) Identification of a specific α-synuclein peptide (α-Syn 29-40) capable of eliciting microglial superoxide production to damage dopaminergic neurons. BioMed Central; DOI: 10.1186/s12974-016-0606-7.
Tomasz Brudek, Kristian Winge, Nadja Bredo Rasmussen, Justyna Maria Bahl Czarna, Julia Tanassi, Tina Klitmøller Agander, Thomas M. Hyde, and Bente Pakkenberg (2015) Altered Alpha-Synuclein, Parkin, and Synphilin Isoform Levels in Multiple System Atrophy Brains. Wiley Online Library; DOI: 10.1111/jnc.13392.
Sandeep K. Sharma, Erik Chorell, Pernilla Wittung-Stafshede (2015) Insulin-degrading enzyme is activated by the C-terminus of α-synuclein. Science Direct; doi:10.1016/j.bbrc.2015.09.002.
Joe Kakish, Dongsoo Lee, and Jeremy Stuart Lee (2015) Drugs which bind to alpha-synuclein. Neuroprotective or neurotoxic?. ACS Chemical; DOI: 10.1021/acschemneuro.5b00172.
Mari Suzuki, Nobuhiro Fujikake, Toshihide Takeuchi, Ayako Kohyama-Koganeya, Kazuki Nakajima, Yoshio Hirabayashi, Keiji Wada and Yoshitaka Nagai (2015) Glucocerebrosidase deficiency accelerates the accumulation of proteinase K-resistant α-synuclein and aggravates neurodegeneration in a Drosophila model of Parkinson's disease. Oxford Journals; doi: 10.1093/hmg/ddv372.
Sandeep K. Sharma, Erik Chorell, Pernilla Wittung-Stafshede (2015) Insulin-degrading enzyme is activated by the C-terminus of α-synuclein. ScienceDirect; doi:10.1016/j.bbrc.2015.09.002.
Iban Aldecoa, Judith Navarro-Otano, Nadia Stefanova, Fabienne S. Sprenger, Klaus Seppi, Werner Poewe, Miriam Cuatrecasas, Francesc Valldeoriolab, c, Ellen Gelpif, Eduard Tolosa (2015) Alpha-synuclein immunoreactivity patterns in the enteric nervous system. ScienceDirect; doi:10.1016/j.neulet.2015.07.005.
Andrew F. Fischer, Kathryn Mansfield Matera (2015) Stabilization of Alpha-Synuclein Oligomers In Vitro by the Neurotransmitters, Dopamine and Norepinephrine: The Effect of Oxidized Catecholamines. Springer Link; DOI: 10.1007/s11064-015-1597-y.
Tatiana K. Rostovtseva, Philip A. Gurnev, Olga Protchenko, David P. Hoogerheide, Thai Leong Yap, Caroline C. Philpott, Jennifer C. Lee, and Sergey M. Bezrukov (2015) Alpha Synuclein Shows High-Affinity Interaction with Voltage-Dependent Anion Channel Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease. JBC Papers in Press; doi:10.1074/jbc.M115.641746.
Staffan Holmqvista, Marinka Brouwer, Mehdi Djelloul, Alejandro Garcia Diaz, Michael J. Devine, Anna Hammarbergf, Karina Fog, Tilo Kunath, Laurent Roybon (2015) Generation of human pluripotent stem cell reporter lines for the isolation of and reporting on astrocytes generated from ventral midbrain and ventral spinal cord neural progenitors. ScienceDirect; doi:10.1016/j.scr.2015.05.014.
Ryoichi Takahashi, Kenjiro Ono, Yusaku Takamura, Mineyuki Mizuguchi, Tokuhei Ikeda, Hisao Nishijo andMasahito Yamada (2015) Phenolic compounds prevent the oligomerization of α-synuclein and reduce synaptic toxicity. JNC Journal of Neurochemistry; DOI: 10.1111/jnc.13180.
Tatiana K. Rostovtseva, Philip A. Gurnev, Olga Protchenko, David P. Hoogerheide, Thai Leong Yap, Caroline C. Philpott, Jennifer C. Lee and Sergey M. Bezrukov (2015) α-Synuclein Shows High Affinity Interaction with Voltage-dependent Anion Channel, Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease. The Journal of Biological Chemistry; doi: 10.1074/jbc.M115.641746.


S.N. Pchelina, E.P. Nuzhnyib, A.K. Emelyanov,T.M. Boukina, T.S. Usenko, M.A. Nikolaev, G.N. Salogub, A.F. Yakimovskii, E.Yu. Zakharova (2014) Increased plasma oligomeric alpha-synuclein in patients with lysosomal storage diseases. Science Direct; doi:10.1016/j.neulet.2014.09.041.
John F. Kellie, Richard E. Higgs, John W. Ryder, Anthony Major, Thomas G. Beach, Charles H. Adler, Kalpana Merchant, & Michael D. Knierman (2014) Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry. Scientific Reports; doi:10.1038/srep05797.
Omid Tavassoly, Joe Kakish, Sergiy Nokhrin, Oleg Dmitriev, Jeremy S. Lee (2014) The use of nanopore analysis for discovering drugs which bind to α-synuclein for treatment of Parkinson's disease. Science Direct; DOI: 10.1016/j.ejmech.2014.07.090.
Gyan Modi, Chandrashekhar Voshavar, Sanjib Gogoi, Mrudang Shah, Tamara Antonio, Maarten E. A. Reith, and Aloke K. Dutta (2014) Multifunctional D2/D3 Agonist D-520 with High in Vivo Efficacy: Modulator of Toxicity of Alpha-Synuclein Aggregates. ACS Publications; DOI: 10.1021/cn500084x.
Guoxiang Liu, Jia Yu, Jinhui Ding, Chengsong Xie, Lixin Sun, Iakov Rudenko, Wang Zheng, Namratha Sastry, Jing Luo, Gay Rudow, Juan C. Troncoso, and Huaibin Cai (2014) Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation. JCI: The Journal of Clinical Investigation; doi:10.1172/JCI72176..
Omid Tavassoly, Sergiy Nokhrin, Oleg Y. Dmitriev, and Jeremy S. Lee (2014) Cu(II) and dopamine bind to α-Synuclein and cause large conformational changes. FEBS Journal; DOI: 10.1111/febs.12817 (Pay to View).
Magdalena Gąssowska, Grzegorz A. Czapski, Beata Pająk, Magdalena Cieślik, Anna M. Lenkiewicz, Agata Adamczyk (2014) Extracellular α-Synuclein Leads to Microtubule Destabilization via GSK-3β-Dependent Tau Phosphorylation in PC12 Cells. PLOS One; DOI: 10.1371/journal.pone.0094259.
Methodios Ximerakis, Georgios Pampalakis, Theodoros I. Roumeliotis, Vasia-Samantha Sykioti, Spiros D. Garbis, Leonidas Stefanis, Georgia Sotiropoulou, and Kostas Vekrellis (2014) Resistance of naturally secreted -synuclein to proteolysis. FEBS Journal; doi: 10.1096/fj.13-245852.
Walter Maetzler, Anja Apel, Markus Langkamp, Christian Deuschle, Sarah Selina Dilger, Johannes Georg Stirnkorb, Claudia Schulte, Erwin Schleicher, Thomas Gasser, Daniela Berg (2014) Comparable Autoantibody Serum Levels against Amyloid- and Inflammation-Associated Proteins in Parkinson’s Disease Patients and Controls. PLoS ONE; DOI: 10.1371/journal.pone.0088604.
Srabasti Acharya, Brian M. Safaie, Piriya Wongkongkathep, Magdalena I. Ivanova, Aida Attar, Frank-Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Gal Bitan, and Lisa J. Lapidus (2014) Molecular Basis for Preventing α-Synuclein Aggregation by a Molecular Tweezer. The Journal of Biological Chemistry; doi: 10.1074/jbc.M113.524520.
Markus Mandler, Elvira Valera, Edward Rockenstein, Harald Weninger, Christina Patrick, Anthony Adame, Radmila Santic, Stefanie Meindl, Benjamin Vigl, Oskar Smrzka, Achim Schneeberger, Frank Mattner, Eliezer Masliah (2014) Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials. DOI 10.1007/s00401-014-1256-4; Title Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials Print ISSN 0001-6322 Online ISSN 1432-0533 Publisher Springer Berlin Heidelberg.
Scott Miners, Hayley Moulding, Rohan de Silva, Seth Love (2014) Reduced vascular endothelial growth factor and capillary density in the occipital cortex in dementia with Lewy bodies. DOI: 10.1111/bpa.12130; Accepted manuscript online: 13 FEB 2014 01:41AM EST Manuscript Accepted: 2 FEB 2014.


Rudy Orlando Cedillos (2013) Alpha-Synuclein Aggregates Activate the Nlrp3Inflammasome Following Vesicle Rupture. Loyola eCommons; (2013). Master's Theses. Paper 1859.
Anahit Ghochikyan, Irina Petrushina, Hayk Davtyan, Armine Hovakimyan, Tommy Saing, Arpine Davtyan, David H. Cribbs, Michael G. Agadjanyan (2013) Immunogenicity of epitope vaccines targeting different B cell antigenic determinants of human α-synuclein: Feasibility study. Science Direct; doi:10.1016/j.neulet.2013.12.028.
Ruben Berrocal, Padmaraju Vasudevaraju, Shantinath Satappa Indi, Krothapalli Raja Surya Sambasiva Rao, and K.S. Rao (2013) In vitro Evidence that an Aqueous Extract of Centella asiatica Modulates α-Synuclein Aggregation Dynamics. IOS Press; DOI: 10.3233/JAD-131187 (Pay to View).
Grzegorz A. Czapski, Magdalena Gąssowska, Anna Wilkaniec, Magdalena Cieślik, and Agata Adamczyk (2013) Extracellular alpha-synuclein induces calpain-dependent overactivation of cyclin-dependent kinase 5 in vitro. Elsevier B.V.; (Pay to view).
David Freeman, Rudy Cedillos, Samantha Choyke, Zana Lukic, Kathleen McGuire, Shauna Marvin, Andrew M. Burrage, Stacey Sudholt, Ajay Rana, Christopher O'Connor, Christopher M. Wiethoff, Edward M. Campbell (2013) Alpha-Synuclein Induces Lysosomal Rupture and Cathepsin Dependent Reactive Oxygen Species Following Endocytosis. PLOS One; DOI: 10.1371/journal.pone.0062143.
Douglas G. Walker, Lue LF, Adler CH, Shill HA, Caviness JN, Sabbagh MN, Akiyama H, Serrano GE, Sue LI, Beach TG (2013) Changes in Properties of Serine 129 Phosphorylated α-Synuclein with Progression of Lewy Type Histopathology in Human Brains. Experimental Neurology; Volume 240, February 2013, Pages 190–204; doi 10.1016/j.expneurol.2012.11.020.
Wright, O., Zhang, L., Liu, Y., Yoshimi, T., Zheng, Y. and Tunnacliffe, A. (2013) Critique of the use of fluorescence-based reporters in Escherichia coli as a screening tool for the identification of peptide inhibitors of Aβ42 aggregation. J. Peptide Sci; doi: 10.1002/psc.2474 (Pay to View).
TL Yap, A Velayati, E Sidransky, JC Lee (2013) Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity.. Molecular Genetics and Metabolism; 2013 Jan;108(1):56-64, ISSN 1096-7192, DOI 10.1016/j.ymgme.2012.11.010.


Smith LM, Klaver AC, Coffey MP, Dang L, Loeffler DA. (2012) Effects of intravenous immunoglobulin on alpha synuclein aggregation and neurotoxicity. Int Immunopharmacol; 2012 Sep 28. pii: S1567-5769(12)00270-6. doi: 10.1016/j.intimp.2012.09.007..
Maetzler W, Langkamp M, Lerche S, Godau J, Brockmann K, Gaenslen A, Huber H, Wurster I, Niebler R, Eschweiler GW, Berg D. (2012) Lowered Serum Amyloid-β1-42 Autoantibodies in Individuals with Lifetime Depression. Journal of Alzheimer's Disease; 2012 Jul 5. [Epub ahead of print] DOI: 10.3233/JAD-2012-120625.
Tavassoly, O., Lee, J.S. (2012) Methamphetamine binds to α-synuclein and causes a conformational change which can be detected by nanopore analysis. FEBS Letters; In Press, Uncorrected proof (5 July 2012), doi:10.1016/j.febslet.2012.06.040.
Prabhudesai, S., Sinha, S., Attar, A., Kotagiri, A., Fitzmaurice, AG, Lakshmanan, R., Ivanova, MI, Loo, JA, Klärner, FG and Schrader, T., et al. (2012) A Novel “Molecular Tweezer” Inhibitor of α-Synuclein Neurotoxicity in Vitro and in Vivo. Neurotherapeutics; Volume 9, Number 2 (2012), 464-476, DOI: 10.1007/s13311-012-0105-1.
Vasudevaraju, P., Guerrero, E., Hegde, ML, Collen, TB, Britton, GB, and Rao, KS (2012) New evidence on α-synuclein and Tau binding to conformation and sequence specific GC* rich DNA: Relevance to neurological disorders. J Pharm Bioallied Sci.; 2012 Apr-Jun; 4(2): 112–117. doi: 10.4103/0975-7406.9481; PMCID: PMC3341714.
Kovacs, GG, Wagner, U., Dumont, B., Pikkarainen, M., Osman, AA, Streichenberger, N., Leisser, I., Verchère, J., Baron, T. and Alafuzoff, I., et al. (2012) An antibody with high reactivity for disease-associated α-synuclein reveals extensive brain pathology. Acta Neuropathologica; 2012, DOI: 10.1007/s00401-012-0964-x.
Martin, Z. S., Neugebauer, V., Dineley, K. T., Kayed, R., Zhang, W., Reese, L. C. and Taglialatela, G., (2012) α-Synuclein oligomers oppose long-term potentiation and impair memory through a calcineurin-dependent mechanism: relevance to human synucleopathic diseases.. Journal of Neurochemistry; 120: 440–452. 2012 Feb; doi: 10.1111/j.1471-4159.2011.07576.x.
Tousi, A.S., Buck, D.J., Curtis, T., Davis, R.L. (2012) α-Synuclein potentiates interleukin-1β-induced CXCL10 expression in human A172 astrocytoma cells. Neuroscience Letters; Volume 507, Issue 2, 24 January 2012, Pages 133–136 DOI /10.1016/j.neulet.2011.12.001.


Weihofen, A., Grimm, J. , Nitsch, R. , Hock, C. (2011) Human Anti-Alpha-Synuclein Antibodies. United States Patent Application; United States Patent Application 20110300077; 2011 Dec 8; DOI: y2011/0300077.html..
Couch, Y, Alvarez-Erviti, L., Sibson, NR, Wood, M and Anthony, D. (2011) The acute inflammatory response to intranigral a-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation. Journal of Neuroinflammation; 2011, 8:166.
Fantini, J., Carlus, D., Yahi, N. (2011) The fusogenic tilted peptide (67–78) of α-synuclein is a cholesterol binding domain. Biochimica et Biophysica Acta (BBA) – Biomembranes; Volume 1808, Issue 10, 2011 October, Pages 2343–2351.
Dodel, R., Bacher, M., Besong Agbo, D., Hagemann, S., Balzer-geldsetzer, M. (2011) Naturally occuring autoantibodies against alpha-synuclein that inhibit the aggregation and cytotoxicity of alpha-synuclein. European Patent Application; European Patent Application EP2366714; 2011 Sept. 21.
Coffey C, Shaw L, Trojanowski J (2011) PPMI Parkinson’s Progression Monitoring Initiative : CSF α-synuclein interlaboratory study. Parkinson ‘s Progession Markers Initiative; 2011 July 7 PPMI – SYN – RR-1.
Verhaara, R., Jongenelena, CA,, Gerardb, M., Baekelandt, V., Van Dama, A., Wilhelmusa, MM., Drukarcha, B. (2011) Blockade of enzyme activity inhibits tissue transglutaminase-mediated transamidation of α-synuclein in a cellular model of Parkinson's disease. Neurochemistry International; Volume 58, Issue 7, June 2011, Pages 785–793 DOI: 10.1016/j.neuint.2011.03.004.
Milowska, K., ,Malachowska, M., Gabryelak, T. (2011) PAMAM G4 dendrimers affect the aggregation of α-synuclein. International Journal of Biological Macromolecules; Volume 48, Issue 5, 2011 June 1, Pages 742–746; DOI: 10.1016/j.ijbiomac.2011.02.021..
Fantini, J., Yahi, N. (2011) Molecular Basis for the Glycosphingolipid-Binding Specificity of α-Synuclein: Key Role of Tyrosine 39 in Membrane Insertion. Journal of Molecular Biology; Volume 408, Issue 4, 13 May 2011, Pages 654–669; DOI: 10.1016/j.bbr.2011.03.031.
Choi DH, Kim YJ, Kim YG, Joh TH, Beal MF, Kim YS. (2011) Role of Matrix Metalloproteinase 3-mediated α-Synuclein Cleavage in Dopaminergic Cell Death. J Biol Chem.; 2011 Apr 22;286(16):14168-77. Epub 2011 Feb 17..
Beales, PA, Bergstrom, CL, Geerts, N., Groves, JT, and Vanderlick, K. (2011) Single Vesicle Observations of the Cardiolipin−Cytochrome c Interaction: Induction of Membrane Morphology Changes. Langmuir; 2011 April 19, 27 (10), pp 6107–6115 DOI: 10.1021/la104924c.
Kalia LV, Kalia SK, Chau H, Lozano AM, Hyman BT, et al. (2011) Ubiquitinylation of α-Synuclein by Carboxyl Terminus Hsp70-Interacting Protein (CHIP) Is Regulated by Bcl-2-Associated Athanogene 5 (BAG5). PLoS ONE; 6(2): e14695. 2011 Feb 16; doi:10.1371/journal.pone.0014695.
Gordon R, Hogan CE, Neal ML, Anantharam V, Kanthasamy AG, Kanthasamy A. (2011) A simple magnetic separation method for high-yield isolation of pure primary microglia. J Neurosci Methods; 2011 Jan 15; 194 (2) :287-96. PubMed PMID:21074565..


Mata IF, Shi M, Agarwal P, Chung KA, Edwards KL, Factor SA, Galasko DR, Ginghina C, Griffith A, Higgins DS, Kay DM, Kim H, Leverenz JB, Quinn JF, Roberts JW, Samii A, Snapinn KW, Tsuang DW, Yearout D, Zhang J, Payami H, Zabetian CP. (2010) SNCA variant associated with Parkinson disease and plasma alpha-synuclein level. Arch Neurol; 2010 Nov; 67 (11) :1350-6. PubMed PMID:21060011; PubMed Central PMCID: PMC3010848..
Dragusanu M, Petre BA, Slamnoiu S, Vlad C, Tu T, Przybylski M. (2010) On-line bioaffinity-electrospray mass spectrometry for simultaneous detection, identification, and quantification of protein-ligand interactions. J Am Soc Mass Spectrom; 2010 Oct; 21 (10) :1643-8. PubMed PMID:20692851..
Mougenot AL, Bétemps D, Hogeveen KN, Kovacs GG, Chouaf-Lakhdar L, Milhavet O, Lehmann S, Legastelois S, Pin JJ, Baron TG. (2010) Production of a monoclonal antibody, against human α-synuclein, in a subpopulation of C57BL/6J mice, presenting a deletion of the α-synuclein locus. J Neurosci Methods; 2010 Oct 15; 192 (2) :268-76. PubMed PMID:20709102..
Patrias L. M., Klaver A. C., Coffey M.P., Loeffler D.A. (2010) Specific antibodies to soluble alpha-synuclein conformations in intravenous immunoglobulin preparations. Clinical & Experimental Immunology; Volume 161, Issue 3, pages 527–535, September 2010 DOI: 10.1111/j.1365-2249.2010.04214.x.
Lee EJ, Woo MS, Moon PG, Baek MC, Choi IY, Kim WK, Junn E, Kim HS. (2010) Alpha-synuclein activates microglia by inducing the expressions of matrix metalloproteinases and the subsequent activation of protease-activated receptor-1. J Immunol; 2010 Jul 1; 185 (1) :615-23. PubMed PMID:20511551..
Liu J, Shi M, Hong Z, Zhang J, Bradner J, Quinn T, Beyer RP, Mcgeer PL, Chen S, Zhang J. (2010) Identification of ciliary neurotrophic factor receptor alpha as a mediator of neurotoxicity induced by alpha-synuclein. Proteomics; 2010 Jun; 10 (11) :2138-50. PubMed PMID:20340160; PubMed Central PMCID: PMC3013276..
Hong, Z., Shi, M., Chung, K.A., Quinn, J.F., Peskind, E.R., Galasko, D., Jankovic, J., Zabetian, C.P., Leverenz, J.B., Baird, G., Montine, T.J., Hancock, A.M., Hwang, H., Pan, C., Bradner, J., Kang, U.J., Jensen, P.H., Zhang, J. (2010) DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease. Brain; 133 (3): 713-726. doi: 10.1093/brain/awq008.


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