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Synuclein Citations

2019

Li-fan Zhang, Xiao-lin Yu, Mei Ji, Shu-ying Liu, Xiao-ling Wu, Yu-jiong Wang, Rui-tian Liu (2019) Resveratrol alleviates motor and cognitive deficits and neuropathology in the A53T α-synuclein mouse model of Parkinson's disease. Food & Function; DOI: 10.1039/c8fo00964c.
Markus Mandler, Edward Rockenstein, Cassia Overk, Michael Mante, Jazmin Florio, Anthony Adame, Changyoun Kim, Radmila Santic, Achim Schneeberger, Frank Mattner, Sabine Schmidhuber, Gergan Galabova, Brian Spencer, Eliezer Masliah, Robert A.Rissman (2019) Effects of single and combined immunotherapy approach targeting amyloid β protein and α-synuclein in a dementia with Lewy bodies-like model.. Alzheimers Dement.; doi: 10.1016/j.jalz.2019.02.002.
Ying Guo, Xinbing Wei, Hua Yan, Yue Qin, Shaoqi Yan, Jia Liu, Yong Zhao, Fan Jiang, and Haiyan Lou (2019) TREM2 deficiency aggravates α-synuclein–induced neurodegeneration and neuroinflammation in Parkinson’s disease models.. FASEB J.; DOI: 10.1096/fj.201900992R.
Sarah Jinn, Cornelis Blauwendraat, Dawn Toolan, Cheryl A Gretzula, Robert E Drolet, Sean Smith, Mike A Nalls, Jacob Marcus, Andrew B Singleton, David J Stone (2019) Functionalization of the TMEM175 p.M393T Variant as a risk factor for Parkinson Disease.. Hum Mol Genet.; DOI: 10.1093/hmg/ddz136.
Veselin Grozdanov, Luc Bousset, Meike Hoffmeister, Corinna Bliederhaeuser, Christoph Meier, Karine Madiona, Laura Pieri, Martin Kiechle, Pamela J. McLean, Jan Kassubek, Christian Behrends, Albert C Ludolph, Jochen H Weishaupt, Ronald Melki, Karin M Danzer (2019) Increased Immune Activation by Pathologic α‐Synuclein in Parkinson's Disease. Annals of Neurology; https://doi.org/10.1002/ana.25557.
Monika Rabenstein Daniela Besong Agbo, Elias Wolfah, Judith Dams, Marina Nicolai, Andreas Roeder, Michael Bacher, Richard C. Dodel, Carmen Noelker (2019) Effect of naturally occurring α-synuclein-antibodies on toxic α-synuclein-fragments. Neuroscience Letters; https://doi.org/10.1016/j.neulet.2019.04.004.
Izumi Yasuhiko, Kondo, Naoto, Takahashi Ryosuke, Akaike Akinori, Kume Toshiaki (2019) Reduction of Immunoreactivity Against the C-Terminal Region of the Intracellular α-Synuclein by Exogenous α-Synuclein Aggregates: Possibility of Conformational Changes.. Journal of Parkinson's Disease; doi: 10.3233/JPD-160835..
Mingming Xu, Wendy Loa-Kum-Cheung, Haiyan Zhang, Ronald J. Quinn, George D. Mellick (2019) Identification of a New α-Synuclein Aggregation Inhibitor via Mass Spectrometry Based Screening. ACS Chem. Neurosci.; https://doi.org/10.1021/acschemneuro.9b00092.
Jintang Wang, Zheng Chen, Jeremy D. Walston, Peisong Gao, Maolong Gao, Sean X. Leng (2019) Interferon-γ Potentiates α-Synuclein-induced Neurotoxicity Linked to Toll-like Receptors 2 and 3 and Tumor Necrosis Factor-α in Murine Astrocytes.. Mol Neurobiol.; DOI: 10.1007/s12035-019-1567-5.
John D. Graef, Nina Hoque, Craig Polson, Ling Yang, Lawrence Iben, Yang Cao, Nino Devidze, Michael K. Ahlijanian, Jere E. Meredith Jr. (2019) Characterization of pathology-inducing α-synuclein species from human diseased brain tissue. bioRxiv; doi: https://doi.org/10.1101/588335.
ShaoPei Li, Kagan Kerman (2019) Electrochemical Detection of Interaction between Copper(II) and Peptides Related to Pathological α-Synuclein Mutants. Anal Chem.; DOI: 10.1021/acs.analchem.8b03612.
Ashim Paul, Bo-Dou Zhang, Satabdee Mohapatra, Gao Li, Yan-Mei Li, Ehud azit, and Daniel Segal (2019) Novel Mannitol-Based Small Molecules for Inhibiting Aggregation of α-Synuclein Amyloids in Parkinson's Disease. Frontiers; https://doi.org/10.3389/fmolb.2019.00016.
Małgorzata Gizyṅska, Julia Witkowska, Przemysław Karpowicz, Rafał Rostankowski,Estrella S. Chocron, Andrew M. Pickering, Pawel Osmulski, Maria Gaczynska,and Elzbieta Jankowska ̇ * (2019) Proline- and Arginine-Rich Peptides as Flexible Allosteric Modulators of Human Proteasome Activity. Journal of Medicinal Chemistry; DOI: 10.1021/acs.jmedchem.8b01025.
Miroslav Radman, Anita Krisko (2019) Protein Damage in Aging and Age-Related Diseases. Open Biology; https://doi.org/10.1098/rsob.180249.
Di Hu, Xiaoyan Sun, Xudong Liao, Xinwen Zhang, Sara Zarabi,..Xin Qi (2019) Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity. Springer Berlin Heidelberg; https://doi.org/10.1007/s00401-019-01993-2.
Lap Ho, Danyue Zhao, Kenjiro Ono, Kai Ruan, Ilaria Mogno, Mayumi Tsuji, Eileen Carry, Justin Brathwaite, Steven Sims, Tal Frolinger, Susan Westfall, Paolo Mazzola, Qingli Wu, Ke Hao, Thomas E. Lloyd, James E. Simon, Jeremiah Faith, Giulio M. Pasinetti (2019) Heterogeneity in gut microbiota drive polyphenol metabolism that influences α-synuclein misfolding and toxicity. The Journal of Nutritional Biochemistry; https://doi.org/10.1016/j.jnutbio.2018.10.019.
Eric S. Luth, Irina G. Stavrovskaya (2019) Measuring Mitochondrial Dysfunction Caused by Soluble α-Synuclein Oligomers. Humana Press, New York, NY; https://doi.org/10.1007/978-1-4939-9124-2_14.
Niccolò Candelise Matthias Schmitz Franc Llorens Anna Villar‐Piqué Maria Cramm Tobias Thom Susana Margarida da Silva Correia José Eriton Gomes da Cunha Wiebke Möbius Tiago F. Outeiro Valentina González Álvarez Martina Banchelli Cristiano D'Andrea Marella de Angelis Saima Zafar Alberto Rabano Paolo Matteini (2019) Seeding variability of different alpha synuclein strains in synucleinopathies. Annals of Neurology; https://doi.org/10.1002/ana.25446.
Anna Wilkaniec, Anna M. Lenkiewicz, Grzegorz A. Czapski, Henryk M. Jęśko, Wojciech Hilgier, Robert Brodzik, Magdalena Gąssowska-Dobrowolska, Carsten Culmsee, Agata Adamczyk (2019) Extracellular Alpha-Synuclein Oligomers Induce Parkin S-Nitrosylation: Relevance to Sporadic Parkinson’s Disease Etiopathology. Springer; https://doi.org/10.1007/s12035-018-1082-0.
Susan M.L. Banks, Audrey T. Medeiros, Molly McQuillan, David J. Busch, Ana Sofia Ibarraran-Viniegra, Subhojit Roy, Rui Sousa, Eileen M. Lafer, Jennifer R. Morgan (2019) Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess α-Synuclein at Synapses. Journal of Neuroscience; https://doi.org/10.1101/517524.

2018

Andreas Weihofen, YuTing Liu, Joseph W. Arndt, Christian Huy, Chao Quan, Benjamin A. Smith, Jean-Luc Baeriswyl, Nicole Cavegn, Luzia Senn, Lihe Su, Galina Marsh, Pavan Auluck, Fabio Montrasio, Roger M. Nitsch, Warren D. Hirst, Jesse M. Cedarbaum, R. Blake Pepinsky, Jan Grimm, Paul H. Weinreb (2018) Development of an aggregate-selective, human-derived α-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models. www.sciencedirect.com; https://doi.org/10.1016/j.nbd.2018.10.016.
Ross S. Mancini, Yanfei Wang, and Donald F. Weaver (2018) Phenylindanes in Brewed Coffee Inhibit Amyloid-Beta and Tau Aggregation. Frontiers; https://doi.org/10.3389/fnins.2018.00735.
Vibha Prasad, Yasmine Wasser, Friederike Hans, Anand Goswami, Istvan Katona, Tiago F. Outeiro, Philipp J. Kahle, Jörg B. Schulz, and Aaron Voigt (2018) Monitoring α-synuclein multimerization in vivo.. FASEB Journal; https://doi.org/10.1096/fj.201800148RRR.
Matthias Schmitz, Anna Villar-Piqué, Franc Llorens, Karin Gmitterová, Peter Hermann, Daniela Varges, Saima Zafar, Paul Lingor, Hugo Vanderstichele, Leentje Demeyer, Erik Stoops, John Q Trojanowski, Virginia M-Y Lee, Inga Zerr (2018) Cerebrospinal Fluid Total and Phosphorylated α-Synuclein in Patients with Creutzfeldt–Jakob Disease and Synucleinopathy. Molecular Neurobiology; doi: 10.1007/s12035-018-1313-4.
Alexandra Albus, Maike Gold, Jan-Philipp Bach, Monika Burg-Roderfeld, Marit Jördens, Yvonne Kirchhein, Yannick Kronimus, David Mengel, Inga Zerr, Richard Dodel (2018) Extending the functional characteristics of naturally occurring autoantibodies against β-Amyloid, Prion Protein and α-Synuclein. PLOS ONE; https://doi.org/10.1371/journal.pone.0202954.
Jintang Wang Zheng Chen Jeremy D. Walston Peisong Gao Maolong Gao Sean X. Leng (2018) α‐Synuclein activates innate immunity but suppresses interferon‐γ expression in murine astrocytes.. Eur J Neurosci.; https://doi.org/10.1111/ejn.13956.
Anna Wilkaniec, Anna M. Lenkiewicz, Grzegorz A. Czapski, Henryk M. Jęśko, Wojciech Hilgier, Robert Brodzik, Magdalena Gąssowska-Dobrowolska, Carsten Culmsee, Agata Adamczyk (2018) Extracellular Alpha-Synuclein Oligomers Induce Parkin S-Nitrosylation: Relevance to Sporadic Parkinson’s Disease Etiopathology. link.springer.com; 10.1007/s12035-018-1082-0.
Liyan Hou, Xiuqi Bao, Caixia Zang, Hanyu Yang, Fuqiang Sun, Yuning Che, Xuefei Wu, Shao Li, Dan Zhang, Qingshan Wang (2018) Integrin CD11b mediates α-synuclein-induced activation of NADPH oxidase through a Rho-dependent pathway. Science Direct; https://doi.org/10.1016/j.redox.2017.11.010.
Motyl, J., Wencel, P.L., Cieślik, M. Strosznajder,R.P., Strosznajder,J.B. (2018) Alpha-synuclein alters differently gene expression of Sirts, PARPs and other stress response proteins: implications for neurodegenerative disorders.. link.springer.com; https://doi.org/10.1007/s12035-016-0317-1.
Rebecca Ann Chmielowski (2018) DESIGN OF ANTIOXIDANT NANOTHERAPEUTICS FOR ATTENUATION OF ATHEROGENESIS AND NEUROINFLAMMATION. School of Graduate Studies Electronic Theses and Dissertations; https://doi.org/doi:10.7282/T32N55GH.

2017

Goldman, J.G., Andrews, H., Amara, A., Naito, A., Alcalay, R.N.,…Kang, U.K. (2017) Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features.. onlinelibrary.wiley.com; https://doi.org/10.1002/mds.27232.
Vandana Deora, Eduardo A. Albornoz, Kevin Zhu, Trent M. Woodruff, Richard Gordon (2017) The Ketone Body β-Hydroxybutyrate Does Not Inhibit Synuclein Mediated Inflammasome Activation in Microglia.. Journal of Neuroimmune Pharmocology; doi: 10.1007/s11481-017-9754-5..
Patrick Oeckl, Petra Steinacker, and Markus Otto (2017) Comparison of Internal Standard Approaches for SRM Analysis of Alpha-Synuclein in Cerebrospinal Fluid. https://pubs.acs.org; 10.1021/acs.jproteome.7b00660.
Hiroyuki Watanabe, Taisuke Ariyoshi, Akihiko Ozaki, Masafumi Ihara, Masahiro Ono, Hideo Saji (2017) Synthesis and biological evaluation of novel radioiodinated benzimidazole derivatives for imaging α-synuclein aggregates. www.sciencedirect.com; https://doi.org/10.1016/j.bmc.2017.10.010.
Junichi Matsumoto, Tessandra Stewart, Lifu Sheng, Na Li, Kristin Bullock, Ning Song, Min Shi, William A Banks, Jing ZhangEmail (2017) Transmission of α-synuclein-containing erythrocyte-derived extracellular vesicles across the blood-brain barrier via adsorptive mediated transcytosis: another mechanism for initiation and progression of Parkinson’s disease?. actaneurocomms.biomedcentral.com; 10.1186/s40478-017-0470-4.
Marika Doucet, Aadil El-Turabi, Franziska Zabel, Benjamin H.M. Hunn, Nora Bengoa-Vergniory, ilena Cioroch, Mauricio Ramm, Amy M. Smith, Ariane Cruz Gomes, Gustavo Cabral de Miranda, Richard Wade-Martins, Martin F. Bachmann (2017) Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles.. PLoS One; https://doi.org/10.1371/journal.pone.0181844.
Sovanarak Lek, Javier Vargas-Medrano, Ernesto Villanueva, Brian S. Marcus, Wesley Godfrey (2017) Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free Assays.. Journal of Visualized Expirements; doi: 10.3791/55361.
Vasquez Velmarinia, Mitra Joya, Hegde Pavana M., Pandey Arvinda, Sengupta Shiladityaa, Mitra Sankara, Rao K.S., Hegde Muralidhar L (2017) Chromatin-Bound Oxidized α-Synuclein Causes Strand Breaks in Neuronal Genomes in in vitro Models of Parkinson’s Disease.. Journal of Alzheimer's Disease; doi: 10.3233/JAD-170342..
James Scott Miners; Seth Love (2017) Endothelin‐converting enzymes degrade α‐synuclein and are reduced in dementia with Lewy bodies. Online Library; https://doi.org/10.1111/jnc.13974.
Juhyun Song, Byeong C.Kim, Dai-Trang T.Nguyen, Manikandan Samidurai, Seong-Min Choib (2017) Levodopa (L-DOPA) attenuates endoplasmic reticulum stress response and cell death signaling through DRD2 in SH-SY5Y neuronal cells under α-synuclein-induced toxicity.. Neuroscience; doi: 10.1016/j.neuroscience.2017.06.060..
Hayk Davtyan, Karen Zagorski, Irina Petrushina, Konstantin Kazarian, Natalie R.S.Goldberg, Janet Petrosyan, Mathew Blurton-Jones, Eliezer Masliah, David H.Cribbs, Michael G.Agadjanyan, Anahit Ghochikyan (2017) MultiTEP platform–based DNA vaccines for alpha-synucleinopathies: pre clinical evaluation of immunogenicity and therapeutic potency. Journal of the Alzheimer's Association; https://doi.org/10.1016/j.jalz.2017.06.168.
Tomasz Brudek, Kristian Winge, Jonas Folke, Søren Christensen, Karina Fog, Bente Pakkenberg and Lars Østergaard Pedersen (2017) Autoimmune antibody decline in Parkinson’s disease and Multiple System Atrophy; a step towards immunotherapeutic strategies. BioMedCentral; https://doi.org/10.1186/s13024-017-0187-7.
Hugo Vanderstichele, Leentje Demeyer, Shorena Janelidze, Els Coart, Erik Stoops, Kimberley Mauroo, Victor Herbst, Cindy François and Oskar Hansson (2017) Recommendations for cerebrospinal fluid collection for the analysis by ELISA of neurogranin trunc P75, α-synuclein, and total tau in combination with Aβ(1–42)/Aβ(1–40).. Alzheimer's Research & Therapy; https://doi.org/10.1186/s13195-017-0265-7.
Anna Wilkaniec, Magdalena Gąssowska, Grzegorz A. Czapski, Magdalena Cieślik, Grzegorz Sulkowski, Agata Adamczyk (2017) P2X7 receptor-pannexin 1 interaction mediates extracellular alpha-synuclein-induced ATP release in neuroblastoma SH-SY5Y cells. Springer Link Purinergic Signalling; DOI: 10.1007/s11302-017-9567-2.
James C. Giffina, Robert C. Richardsb, Cheryl Craftc, Nusrat Jahanc, 1, Cindy Leggiadrob, Thierry Chopind, Michael Szemerdae, Shawna L. MacKinnonc, K.Vanya Ewart (2017) An extract of the marine alga Alaria esculenta modulates -synuclein folding and amyloid formation. Elsevier; http://dx.doi.org/10.1016/j.neulet.2017.02.055.
Cagla Sahin, Nikolai Lorenzen, Lasse Lemminger, Gunna Christiansen, Ian Max Møller, Louise Buur Vesterager, Lars Østergaard Pedersen, Karina Fog, Pekka Kallunki, Daniel E. Otzen (2017) Antibodies against the C-terminus of α-synuclein modulate its fibrillation. Science Direct Biophysical Chemistry Volume 220, January 2017, Pages 34–41; http://dx.doi.org/10.1016/j.bpc.2016.11.002.
Elisabet Jakova, Jeremy S. Lee (2017) Behavior of α‐synuclein–drug complexes during nanopore analysis with a superimposed AC field.. Electrophoresis; doi: 10.1002/elps.201600253.
Yunden Jinsmaa, Patricia Sullivan, Yehonatan Sharabi, David S. Goldstein (2017) DOPAL is transmissible to and oligomerizes alpha-synuclein in human glial cells.. NCBI; doi: 10.1016/j.autneu.2015.12.008.
Ismael Segura-Ulate, Barbara Yang, Javier Vargas-Medrano, Ruth G. Perez (2017) FTY720 (Fingolimod) reverses α-synuclein-Induced downregulation of brain-derived neurotrophic factor mRNA in OLN-93 oligodendroglial cells. Science Direct Neuropharmacology; http://dx.doi.org/10.1016/j.neuropharm.2017.01.028.

2016

Leire Almandoz-Gil, Veronica Lindström, Jessica Sigvardson,Philipp J. Kahle, Lars Lannfelt, Martin Ingelsson, Joakim Bergström (2016) Mapping of Surface-Exposed Epitopes of In Vitro and In Vivo Aggregated Species of Alpha-Synuclein. Springer Link Cellular and Molecular Neurobiology; doi:10.1007/s10571-016-0454-0.
Al-Hilaly, Youssra K and Biasetti, Luca and Blakeman, Ben J F and Pollack, Saskia J and Zibaee, Shahin and Abdul-Sada, Alaa and Thorpe, Julian R and Xue, Wei-Feng and Serpell, Louise C (2016) The involvement of dityrosine crosslinking in synuclein assembly and deposition in Lewy Bodies in Parkinson's disease.. Scientific Reports; http://doi.org/10.1038/srep39171.
Wei-Li Kuan, Neal Bennett, Xiaoling He, Jeremy N. Skepper, Nataly Martynyuk, Ruwani Wijeyekoon, Prabhas V. Moghe, Roger A. Barker (2016) α-Synuclein pre-formed fibrils impair tight junction protein expression without affecting cerebral endothelial cell function.. EXP Neurol.; doi: 10.1016/j.expneurol.2016.09.003..
Suraj S. Pradhan, Kirstie Salinas, Alexis C. Garduno, Jenny U. Johansson, Qian Wang, Amy Manning-Bog (2016) Anti-Inflammatory and Neuroprotective Effects of PGE2 EP4 Signaling in Models of Parkinson’s Disease.. Journal of Neuroimmune Pharmocology; doi: 10.1007/s11481-016-9713-6..
Nadja Bredo Rasmussen, Mikkel Vestergaard Olesen, Tomasz Brudek, Per Plenge, Anders Bue Klein, Jenny E. Westin, Karina Fog, Gitta Wörtwein, Susana Aznar (2016) 5-HT2A Receptor Binding in the Frontal Cortex of Parkinson’s Disease Patients and Alpha-Synuclein Overexpressing Mice: A Postmortem Study. Parkinson’s Disease; http://dx.doi.org/10.1155/2016/3682936.
Dolores Vilas, Leslie M. Shaw, Peggy Taylor, Daniela Berg, Kathrin Brockmann, Jan Aasly, Connie Marras, Claustre Pont‐Sunyer, José Ríos, Ken Marek, Eduardo Tolosa (2016) Cerebrospinal fluid biomarkers and clinical features in leucine‐rich repeat kinase 2 (LRRK2) mutation carriers.. Mov Disord.; doi: 10.1002/mds.26591..
Richard Gordon, Neeraj Singh, Vivek Lawana, Anamitra Ghosh, Dilshan S. Harischandra, Huajun Jin, Colleen Hogan, Souvarish Sarkar, Dharmin Rokad, Nikhil Panicker, Vellareddy Anantharam, Anumantha G. Kanthasamy, Arthi Kanthasamy (2016) Protein Kinase Cδ Upregulation in Microglia Drives Neuroinflammatory Responses and Dopaminergic Neurodegeneration in Experimental Models of Parkinson's Disease. NCBI; doi: 10.1016/j.nbd.2016.04.008.
Manna F. Iwabuchi, Marcel M. Hetu, William G.Tong (2016) Sensitive analysis of α-synuclein by nonlinear laser wave mixing coupled with capillary electrophoresis.. Analytical Biochem.; doi: 10.1016/j.ab.2016.01.010.
Masahiro Ono, Yuki Doi, Hiroyuki Watanabe, Masafumi Ihara, Akihiko Ozaki, Hideo Saji (2016) Structure–activity relationships of radioiodinated diphenyl derivatives with different conjugated double bonds as ligands for α-synuclein aggregates.. RSC Advances; DOI: 10.1039/C6RA02710E.
Teng Ai, Daniel J. Wilson, Swati S. More, Jiashu Xie, and Liqiang Chen (2016) 5-((3-Amidobenzyl)oxy)nicotinamides as Sirtuin 2 Inhibitors. ACS Publications; DOI: 10.1021/acs.jmedchem.5b01376.
Yunden Jinsmaa, Patricia Sullivan, Yehonatan Sharabi, David S. Goldstein (2016) DOPAL is transmissible to and oligomerizes alpha-synuclein in human glial cells. Autonomic Neuroscience; DOI: http://dx.doi.org/10.1016/j.autneu.2015.12.008.

2015

Shijun Wang, Chun-Hsien Chu, Mingri Guo, Lulu Jiang, Hui Nie, Wei Zhang, Belinda Wilson, Li Yang, Tessandra Stewart, Jau-Shyong HongEmail author and Jing Zhang (2015) Identification of a specific α-synuclein peptide (α-Syn 29-40) capable of eliciting microglial superoxide production to damage dopaminergic neurons. BioMed Central; DOI: 10.1186/s12974-016-0606-7.
Tomasz Brudek, Kristian Winge, Nadja Bredo Rasmussen, Justyna Maria Bahl Czarna, Julia Tanassi, Tina Klitmøller Agander, Thomas M. Hyde, and Bente Pakkenberg (2015) Altered Alpha-Synuclein, Parkin, and Synphilin Isoform Levels in Multiple System Atrophy Brains. Wiley Online Library; DOI: 10.1111/jnc.13392.
Sandeep K. Sharma, Erik Chorell, Pernilla Wittung-Stafshede (2015) Insulin-degrading enzyme is activated by the C-terminus of α-synuclein. Science Direct; doi:10.1016/j.bbrc.2015.09.002.
Joe Kakish, Dongsoo Lee, and Jeremy Stuart Lee (2015) Drugs which bind to alpha-synuclein. Neuroprotective or neurotoxic?. ACS Chemical; DOI: 10.1021/acschemneuro.5b00172.
Mari Suzuki, Nobuhiro Fujikake, Toshihide Takeuchi, Ayako Kohyama-Koganeya, Kazuki Nakajima, Yoshio Hirabayashi, Keiji Wada and Yoshitaka Nagai (2015) Glucocerebrosidase deficiency accelerates the accumulation of proteinase K-resistant α-synuclein and aggravates neurodegeneration in a Drosophila model of Parkinson's disease. Oxford Journals; doi: 10.1093/hmg/ddv372.
Sandeep K. Sharma, Erik Chorell, Pernilla Wittung-Stafshede (2015) Insulin-degrading enzyme is activated by the C-terminus of α-synuclein. ScienceDirect; doi:10.1016/j.bbrc.2015.09.002.
Iban Aldecoa, Judith Navarro-Otano, Nadia Stefanova, Fabienne S. Sprenger, Klaus Seppi, Werner Poewe, Miriam Cuatrecasas, Francesc Valldeoriolab, c, Ellen Gelpif, Eduard Tolosa (2015) Alpha-synuclein immunoreactivity patterns in the enteric nervous system. ScienceDirect; doi:10.1016/j.neulet.2015.07.005.
Tianfang Jiang, Jake Hoekstra, Xin Heng, Wenyan Kang, Jianqing Ding, Jun Liu, Shengdi Chen, Jing Zhang (2015) P2X7 receptor is critical in α-synuclein–mediated microglial NADPH oxidase activation.. Neurobiol. Aging; doi: 10.1016/j.neurobiolaging.2015.03.015.
Andrew F. Fischer, Kathryn Mansfield Matera (2015) Stabilization of Alpha-Synuclein Oligomers In Vitro by the Neurotransmitters, Dopamine and Norepinephrine: The Effect of Oxidized Catecholamines. Springer Link; DOI: 10.1007/s11064-015-1597-y.
Tatiana K. Rostovtseva, Philip A. Gurnev, Olga Protchenko, David P. Hoogerheide, Thai Leong Yap, Caroline C. Philpott, Jennifer C. Lee, and Sergey M. Bezrukov (2015) Alpha Synuclein Shows High-Affinity Interaction with Voltage-Dependent Anion Channel Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease. JBC Papers in Press; doi:10.1074/jbc.M115.641746.
Staffan Holmqvista, Marinka Brouwer, Mehdi Djelloul, Alejandro Garcia Diaz, Michael J. Devine, Anna Hammarbergf, Karina Fog, Tilo Kunath, Laurent Roybon (2015) Generation of human pluripotent stem cell reporter lines for the isolation of and reporting on astrocytes generated from ventral midbrain and ventral spinal cord neural progenitors. ScienceDirect; doi:10.1016/j.scr.2015.05.014.
Ryoichi Takahashi, Kenjiro Ono, Yusaku Takamura, Mineyuki Mizuguchi, Tokuhei Ikeda, Hisao Nishijo andMasahito Yamada (2015) Phenolic compounds prevent the oligomerization of α-synuclein and reduce synaptic toxicity. JNC Journal of Neurochemistry; DOI: 10.1111/jnc.13180.
Tatiana K. Rostovtseva, Philip A. Gurnev, Olga Protchenko, David P. Hoogerheide, Thai Leong Yap, Caroline C. Philpott, Jennifer C. Lee and Sergey M. Bezrukov (2015) α-Synuclein Shows High Affinity Interaction with Voltage-dependent Anion Channel, Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease. The Journal of Biological Chemistry; doi: 10.1074/jbc.M115.641746.

2014

Scott Miners, Ruth Renfrew, Marta Swirski, Seth Love (2014) Accumulation of α-synuclein in dementia with Lewy bodies is associated with decline in the α-synuclein-degrading enzymes kallikrein-6 and calpain-1.. Acta Neuropathol Commun.; doi: 10.1186/s40478-014-0164-0..
Sebastian Heinzel , Maike Gold, Christian Deuschle, Felix Bernhard, Walter Maetzler, Daniela Berg, Richard Dodel (2014) Naturally Occurring Alpha-Synuclein Autoantibodies in Parkinson’s Disease: Sources of (Error) Variance in Biomarker Assays.. PLoS One; https://doi.org/10.1371/journal.pone.0114566.
S.N. Pchelina, E.P. Nuzhnyib, A.K. Emelyanov,T.M. Boukina, T.S. Usenko, M.A. Nikolaev, G.N. Salogub, A.F. Yakimovskii, E.Yu. Zakharova (2014) Increased plasma oligomeric alpha-synuclein in patients with lysosomal storage diseases. Science Direct; doi:10.1016/j.neulet.2014.09.041.
Min Shi, Changqin Liu, Travis J. Cook, Kristin M. Bullock, Yanchun Zhao, Carmen Ginghina, Yanfei Li, Patrick Aro, Romel Dator, Chunmei He, Michael J. Hipp, Cyrus P. Zabetian, Elaine R. Peskind, Shu-Ching Hu, Joseph F. Quinn, Douglas R. Galasko, William A. Banks, Jing Zhang (2014) Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson’s disease.. Acta Neurolpathol.; doi: 10.1007/s00401-014-1314-y.
John F. Kellie, Richard E. Higgs, John W. Ryder, Anthony Major, Thomas G. Beach, Charles H. Adler, Kalpana Merchant, & Michael D. Knierman (2014) Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry. Scientific Reports; doi:10.1038/srep05797.
Omid Tavassoly, Joe Kakish, Sergiy Nokhrin, Oleg Dmitriev, Jeremy S. Lee (2014) The use of nanopore analysis for discovering drugs which bind to α-synuclein for treatment of Parkinson's disease. Science Direct; DOI: 10.1016/j.ejmech.2014.07.090.
Gyan Modi, Chandrashekhar Voshavar, Sanjib Gogoi, Mrudang Shah, Tamara Antonio, Maarten E. A. Reith, and Aloke K. Dutta (2014) Multifunctional D2/D3 Agonist D-520 with High in Vivo Efficacy: Modulator of Toxicity of Alpha-Synuclein Aggregates. ACS Publications; DOI: 10.1021/cn500084x.
Guoxiang Liu, Jia Yu, Jinhui Ding, Chengsong Xie, Lixin Sun, Iakov Rudenko, Wang Zheng, Namratha Sastry, Jing Luo, Gay Rudow, Juan C. Troncoso, and Huaibin Cai (2014) Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation. JCI: The Journal of Clinical Investigation; doi:10.1172/JCI72176..
Omid Tavassoly, Sergiy Nokhrin, Oleg Y. Dmitriev, and Jeremy S. Lee (2014) Cu(II) and dopamine bind to α-Synuclein and cause large conformational changes. FEBS Journal; DOI: 10.1111/febs.12817 (Pay to View).
Magdalena Gąssowska, Grzegorz A. Czapski, Beata Pająk, Magdalena Cieślik, Anna M. Lenkiewicz, Agata Adamczyk (2014) Extracellular α-Synuclein Leads to Microtubule Destabilization via GSK-3β-Dependent Tau Phosphorylation in PC12 Cells. PLOS One; DOI: 10.1371/journal.pone.0094259.
Methodios Ximerakis, Georgios Pampalakis, Theodoros I. Roumeliotis, Vasia-Samantha Sykioti, Spiros D. Garbis, Leonidas Stefanis, Georgia Sotiropoulou, and Kostas Vekrellis (2014) Resistance of naturally secreted -synuclein to proteolysis. FEBS Journal; doi: 10.1096/fj.13-245852.
Walter Maetzler, Anja Apel, Markus Langkamp, Christian Deuschle, Sarah Selina Dilger, Johannes Georg Stirnkorb, Claudia Schulte, Erwin Schleicher, Thomas Gasser, Daniela Berg (2014) Comparable Autoantibody Serum Levels against Amyloid- and Inflammation-Associated Proteins in Parkinson’s Disease Patients and Controls. PLoS ONE; DOI: 10.1371/journal.pone.0088604.
Srabasti Acharya, Brian M. Safaie, Piriya Wongkongkathep, Magdalena I. Ivanova, Aida Attar, Frank-Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Gal Bitan, and Lisa J. Lapidus (2014) Molecular Basis for Preventing α-Synuclein Aggregation by a Molecular Tweezer. The Journal of Biological Chemistry; doi: 10.1074/jbc.M113.524520.
Markus Mandler, Elvira Valera, Edward Rockenstein, Harald Weninger, Christina Patrick, Anthony Adame, Radmila Santic, Stefanie Meindl, Benjamin Vigl, Oskar Smrzka, Achim Schneeberger, Frank Mattner, Eliezer Masliah (2014) Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials. DOI 10.1007/s00401-014-1256-4; Title Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials Print ISSN 0001-6322 Online ISSN 1432-0533 Publisher Springer Berlin Heidelberg.
Scott Miners, Hayley Moulding, Rohan de Silva, Seth Love (2014) Reduced vascular endothelial growth factor and capillary density in the occipital cortex in dementia with Lewy bodies. DOI: 10.1111/bpa.12130; Accepted manuscript online: 13 FEB 2014 01:41AM EST Manuscript Accepted: 2 FEB 2014.

2013

Rudy Orlando Cedillos (2013) Alpha-Synuclein Aggregates Activate the Nlrp3Inflammasome Following Vesicle Rupture. Loyola eCommons; (2013). Master's Theses. Paper 1859.
Anahit Ghochikyan, Irina Petrushina, Hayk Davtyan, Armine Hovakimyan, Tommy Saing, Arpine Davtyan, David H. Cribbs, Michael G. Agadjanyan (2013) Immunogenicity of epitope vaccines targeting different B cell antigenic determinants of human α-synuclein: Feasibility study. Science Direct; doi:10.1016/j.neulet.2013.12.028.
Ruben Berrocal, Padmaraju Vasudevaraju, Shantinath Satappa Indi, Krothapalli Raja Surya Sambasiva Rao, and K.S. Rao (2013) In vitro Evidence that an Aqueous Extract of Centella asiatica Modulates α-Synuclein Aggregation Dynamics. IOS Press; DOI: 10.3233/JAD-131187 (Pay to View).
Grzegorz A. Czapski, Magdalena Gąssowska, Anna Wilkaniec, Magdalena Cieślik, and Agata Adamczyk (2013) Extracellular alpha-synuclein induces calpain-dependent overactivation of cyclin-dependent kinase 5 in vitro. Elsevier B.V.; http://dx.doi.org/10.1016/j.febslet.2013.07.053 (Pay to view).
David Freeman, Rudy Cedillos, Samantha Choyke, Zana Lukic, Kathleen McGuire, Shauna Marvin, Andrew M. Burrage, Stacey Sudholt, Ajay Rana, Christopher O'Connor, Christopher M. Wiethoff, Edward M. Campbell (2013) Alpha-Synuclein Induces Lysosomal Rupture and Cathepsin Dependent Reactive Oxygen Species Following Endocytosis. PLOS One; DOI: 10.1371/journal.pone.0062143.
Tamara C. Hornik, Urte Neniskyte, Guy C. BrownInf (2013) Inflammation induces multinucleation of Microglia via PKC inhibition of cytokinesis, generating highly phagocytic multinucleated giant cells. J Neurochem.; doi: 10.1111/jnc.12477.
Ove Jonsson, Ann-Charlott Steffen, Valentina Screpanti Sundquist, Juliette Janson, Stefan Martinsson, Ulrika Määttä, Anna Breitholtz Emanuelsson (2013) Capillary microsampling and analysis of 4-µl blood, plasma and serum samples to determine human α-synuclein elimination rate in mice.. Bioanalysis.; doi: 10.4155/bio.12.337.
Douglas G. Walker, Lue LF, Adler CH, Shill HA, Caviness JN, Sabbagh MN, Akiyama H, Serrano GE, Sue LI, Beach TG (2013) Changes in Properties of Serine 129 Phosphorylated α-Synuclein with Progression of Lewy Type Histopathology in Human Brains. Experimental Neurology; Volume 240, February 2013, Pages 190–204; doi 10.1016/j.expneurol.2012.11.020.
Wright, O., Zhang, L., Liu, Y., Yoshimi, T., Zheng, Y. and Tunnacliffe, A. (2013) Critique of the use of fluorescence-based reporters in Escherichia coli as a screening tool for the identification of peptide inhibitors of Aβ42 aggregation. J. Peptide Sci; doi: 10.1002/psc.2474 (Pay to View).
TL Yap, A Velayati, E Sidransky, JC Lee (2013) Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity.. Molecular Genetics and Metabolism; 2013 Jan;108(1):56-64, ISSN 1096-7192, DOI 10.1016/j.ymgme.2012.11.010.

2012

Smith LM, Klaver AC, Coffey MP, Dang L, Loeffler DA. (2012) Effects of intravenous immunoglobulin on alpha synuclein aggregation and neurotoxicity. Int Immunopharmacol; 2012 Sep 28. pii: S1567-5769(12)00270-6. doi: 10.1016/j.intimp.2012.09.007..
Michael Bidinosti, Derya R. Shimshek, Brit Mollenhauer, David Marcellin, Tatjana Schweizer, Gregor P. Lotz, Michael G. Schlossmacher, Andreas Weiss (2012) https://www.ncbi.nlm.nih.gov/pubmed/22843695. J Biol Chem.; DOI: 10.1074/jbc.M112.379792.
Maetzler W, Langkamp M, Lerche S, Godau J, Brockmann K, Gaenslen A, Huber H, Wurster I, Niebler R, Eschweiler GW, Berg D. (2012) Lowered Serum Amyloid-β1-42 Autoantibodies in Individuals with Lifetime Depression. Journal of Alzheimer's Disease; 2012 Jul 5. [Epub ahead of print] DOI: 10.3233/JAD-2012-120625.
Tavassoly, O., Lee, J.S. (2012) Methamphetamine binds to α-synuclein and causes a conformational change which can be detected by nanopore analysis. FEBS Letters; In Press, Uncorrected proof (5 July 2012), doi:10.1016/j.febslet.2012.06.040.
Prabhudesai, S., Sinha, S., Attar, A., Kotagiri, A., Fitzmaurice, AG, Lakshmanan, R., Ivanova, MI, Loo, JA, Klärner, FG and Schrader, T., et al. (2012) A Novel “Molecular Tweezer” Inhibitor of α-Synuclein Neurotoxicity in Vitro and in Vivo. Neurotherapeutics; Volume 9, Number 2 (2012), 464-476, DOI: 10.1007/s13311-012-0105-1.
Vasudevaraju, P., Guerrero, E., Hegde, ML, Collen, TB, Britton, GB, and Rao, KS (2012) New evidence on α-synuclein and Tau binding to conformation and sequence specific GC* rich DNA: Relevance to neurological disorders. J Pharm Bioallied Sci.; 2012 Apr-Jun; 4(2): 112–117. doi: 10.4103/0975-7406.9481; PMCID: PMC3341714.
Kovacs, GG, Wagner, U., Dumont, B., Pikkarainen, M., Osman, AA, Streichenberger, N., Leisser, I., Verchère, J., Baron, T. and Alafuzoff, I., et al. (2012) An antibody with high reactivity for disease-associated α-synuclein reveals extensive brain pathology. Acta Neuropathologica; 2012, DOI: 10.1007/s00401-012-0964-x.
Martin, Z. S., Neugebauer, V., Dineley, K. T., Kayed, R., Zhang, W., Reese, L. C. and Taglialatela, G., (2012) α-Synuclein oligomers oppose long-term potentiation and impair memory through a calcineurin-dependent mechanism: relevance to human synucleopathic diseases.. Journal of Neurochemistry; 120: 440–452. 2012 Feb; doi: 10.1111/j.1471-4159.2011.07576.x.
Tousi, A.S., Buck, D.J., Curtis, T., Davis, R.L. (2012) α-Synuclein potentiates interleukin-1β-induced CXCL10 expression in human A172 astrocytoma cells. Neuroscience Letters; Volume 507, Issue 2, 24 January 2012, Pages 133–136 DOI /10.1016/j.neulet.2011.12.001.

2011

Weihofen, A., Grimm, J. , Nitsch, R. , Hock, C. (2011) Human Anti-Alpha-Synuclein Antibodies. United States Patent Application; United States Patent Application 20110300077; 2011 Dec 8; DOI: y2011/0300077.html..
Couch, Y, Alvarez-Erviti, L., Sibson, NR, Wood, M and Anthony, D. (2011) The acute inflammatory response to intranigral a-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation. Journal of Neuroinflammation; 2011, 8:166.
Fantini, J., Carlus, D., Yahi, N. (2011) The fusogenic tilted peptide (67–78) of α-synuclein is a cholesterol binding domain. Biochimica et Biophysica Acta (BBA) – Biomembranes; Volume 1808, Issue 10, 2011 October, Pages 2343–2351.
Dodel, R., Bacher, M., Besong Agbo, D., Hagemann, S., Balzer-geldsetzer, M. (2011) Naturally occuring autoantibodies against alpha-synuclein that inhibit the aggregation and cytotoxicity of alpha-synuclein. European Patent Application; European Patent Application EP2366714; 2011 Sept. 21.
Jason Jensen, Margherita Farina, Giampaolo Zuccheri, Wilfried Grange, Martin Hegner (2011) Quantitative, Label-Free Detection of the Aggregation of α-Synuclein Using Microcantilever Arrays Operated in a Liquid Environment.. Journal of Sensors; http://dx.doi.org/10.1155/2012/874086.
Coffey C, Shaw L, Trojanowski J (2011) PPMI Parkinson’s Progression Monitoring Initiative : CSF α-synuclein interlaboratory study. Parkinson ‘s Progession Markers Initiative; 2011 July 7 PPMI – SYN – RR-1.
Verhaara, R., Jongenelena, CA,, Gerardb, M., Baekelandt, V., Van Dama, A., Wilhelmusa, MM., Drukarcha, B. (2011) Blockade of enzyme activity inhibits tissue transglutaminase-mediated transamidation of α-synuclein in a cellular model of Parkinson's disease. Neurochemistry International; Volume 58, Issue 7, June 2011, Pages 785–793 DOI: 10.1016/j.neuint.2011.03.004.
Milowska, K., ,Malachowska, M., Gabryelak, T. (2011) PAMAM G4 dendrimers affect the aggregation of α-synuclein. International Journal of Biological Macromolecules; Volume 48, Issue 5, 2011 June 1, Pages 742–746; DOI: 10.1016/j.ijbiomac.2011.02.021..
Fantini, J., Yahi, N. (2011) Molecular Basis for the Glycosphingolipid-Binding Specificity of α-Synuclein: Key Role of Tyrosine 39 in Membrane Insertion. Journal of Molecular Biology; Volume 408, Issue 4, 13 May 2011, Pages 654–669; DOI: 10.1016/j.bbr.2011.03.031.
Choi DH, Kim YJ, Kim YG, Joh TH, Beal MF, Kim YS. (2011) Role of Matrix Metalloproteinase 3-mediated α-Synuclein Cleavage in Dopaminergic Cell Death. J Biol Chem.; 2011 Apr 22;286(16):14168-77. Epub 2011 Feb 17..
Beales, PA, Bergstrom, CL, Geerts, N., Groves, JT, and Vanderlick, K. (2011) Single Vesicle Observations of the Cardiolipin−Cytochrome c Interaction: Induction of Membrane Morphology Changes. Langmuir; 2011 April 19, 27 (10), pp 6107–6115 DOI: 10.1021/la104924c.
Kalia LV, Kalia SK, Chau H, Lozano AM, Hyman BT, et al. (2011) Ubiquitinylation of α-Synuclein by Carboxyl Terminus Hsp70-Interacting Protein (CHIP) Is Regulated by Bcl-2-Associated Athanogene 5 (BAG5). PLoS ONE; 6(2): e14695. 2011 Feb 16; doi:10.1371/journal.pone.0014695.
Gordon R, Hogan CE, Neal ML, Anantharam V, Kanthasamy AG, Kanthasamy A. (2011) A simple magnetic separation method for high-yield isolation of pure primary microglia. J Neurosci Methods; 2011 Jan 15; 194 (2) :287-96. PubMed PMID:21074565..

2010

Mata IF, Shi M, Agarwal P, Chung KA, Edwards KL, Factor SA, Galasko DR, Ginghina C, Griffith A, Higgins DS, Kay DM, Kim H, Leverenz JB, Quinn JF, Roberts JW, Samii A, Snapinn KW, Tsuang DW, Yearout D, Zhang J, Payami H, Zabetian CP. (2010) SNCA variant associated with Parkinson disease and plasma alpha-synuclein level. Arch Neurol; 2010 Nov; 67 (11) :1350-6. PubMed PMID:21060011; PubMed Central PMCID: PMC3010848..
Dragusanu M, Petre BA, Slamnoiu S, Vlad C, Tu T, Przybylski M. (2010) On-line bioaffinity-electrospray mass spectrometry for simultaneous detection, identification, and quantification of protein-ligand interactions. J Am Soc Mass Spectrom; 2010 Oct; 21 (10) :1643-8. PubMed PMID:20692851..
Mougenot AL, Bétemps D, Hogeveen KN, Kovacs GG, Chouaf-Lakhdar L, Milhavet O, Lehmann S, Legastelois S, Pin JJ, Baron TG. (2010) Production of a monoclonal antibody, against human α-synuclein, in a subpopulation of C57BL/6J mice, presenting a deletion of the α-synuclein locus. J Neurosci Methods; 2010 Oct 15; 192 (2) :268-76. PubMed PMID:20709102..
Patrias L. M., Klaver A. C., Coffey M.P., Loeffler D.A. (2010) Specific antibodies to soluble alpha-synuclein conformations in intravenous immunoglobulin preparations. Clinical & Experimental Immunology; Volume 161, Issue 3, pages 527–535, September 2010 DOI: 10.1111/j.1365-2249.2010.04214.x.
Lee EJ, Woo MS, Moon PG, Baek MC, Choi IY, Kim WK, Junn E, Kim HS. (2010) Alpha-synuclein activates microglia by inducing the expressions of matrix metalloproteinases and the subsequent activation of protease-activated receptor-1. J Immunol; 2010 Jul 1; 185 (1) :615-23. PubMed PMID:20511551..
Liu J, Shi M, Hong Z, Zhang J, Bradner J, Quinn T, Beyer RP, Mcgeer PL, Chen S, Zhang J. (2010) Identification of ciliary neurotrophic factor receptor alpha as a mediator of neurotoxicity induced by alpha-synuclein. Proteomics; 2010 Jun; 10 (11) :2138-50. PubMed PMID:20340160; PubMed Central PMCID: PMC3013276..
Hong, Z., Shi, M., Chung, K.A., Quinn, J.F., Peskind, E.R., Galasko, D., Jankovic, J., Zabetian, C.P., Leverenz, J.B., Baird, G., Montine, T.J., Hancock, A.M., Hwang, H., Pan, C., Bradner, J., Kang, U.J., Jensen, P.H., Zhang, J. (2010) DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease. Brain; 133 (3): 713-726. doi: 10.1093/brain/awq008.

2009

Adamczyk A, Czapski GA, Kamierczak A, Strosznajder JB. (2009) Effect of N-methyl-D-aspartate (NMDA) receptor antagonists on alpha-synuclein-evoked neuronal nitric oxide synthase activation in the rat brain. Pharmacol Rep; 2009 Nov-Dec;61(6):1078-85. PubMed PMID: 20081243..
Parihar MS, Parihar A, Fujita M, Hashimoto M, Ghafourifar P. (2009) Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells. Int J Biochem Cell Biol; 2009 Oct;41(10):2015-24. Epub 2009 May 19. PubMed PMID: 19460457..
Zuo P, Qu W, Cooper RN, Goyer RA, Diwan BA, Waalkes MP. (2009) Potential role of alpha-synuclein and metallothionein in lead-induced inclusion body formation. Toxicol Sci; 2009 Sep;111(1):100-8. Epub 2009 Jun 19. PubMed PMID: 19542206; PubMed Central PMCID: PMC2726298..
Chanthamontri C, Liu J, McLuckey SA. (2009) Charge State Dependent Fragmentation of Gaseous alpha-Synuclein Cations via Ion Trap and Beam-Type Collisional Activation. Int J Mass Spectrom; 2009 Jun 1;283(1-3):9-16. PubMed PMID: 20160958; PubMed Central PMCID: PMC2759116..
Adamczyk A, Kamierczak A. (2009) Alpha-synuclein inhibits poly (ADP-ribose) polymerase-1 (PARP-1) activity via NO-dependent pathway.. Folia Neuropathol; 2009;47(3):247-51. PubMed PMID: 19813144..
Yin S, Loo JA. (2009) Mass spectrometry detection and characterization of noncovalent protein complexes. Methods Mol Biol; 2009;492:273-82. PubMed PMID: 19241039..
Näsström T, Wahlberg T, Karlsson M, Nikolajeff F, Lannfelt L, Ingelsson M, Bergström J. (2009) The lipid peroxidation metabolite 4-oxo-2-nonenal cross-links alpha-synuclein causing rapid formation of stable oligomers. Biochem Biophys Res Commun; 2009 Jan 23;378(4):872-6. Epub 2008 Dec 12. PubMed PMID: 19070597..

2008

Lya, T., Julian, R.R. (2008) Protein–Metal Interactions of Calmodulin and α-Synuclein Monitored by Selective Noncovalent Adduct Protein Probing Mass Spectrometry. Journal of the American Society for Mass Spectrometry; 19(11): 1663-1672..
Grabenauer, M., Bernstein, SL., Lee, JC., Wyttenbach, T., Dupuis, NF., Gary, HB., Winker, JR., Bowers, MT. (2008) Spermine Binding to Parkinson’s Protein α-Synuclein and Its Disease-related A30P and A53T Mutants. The Journal of Physical Chemistry B; 112 (35), pp 11147-11154. DOI abs/10.1021/jp801175w.
Madine, J., Hughes, E., Doig, AJ., Middleton, DA. (2008) The effect of α-synuclein on phospholipid vesicle integrity: a study using 31P NMR and electron mircroscopy. Moleculalr Membrane Biology; Vol. 25, No.6-7, Pages 518-527 DOI abs/10.1080/09687680802467977.
Li, Z.N., Lee, B.J., Langley, W.A., Bradley, K.C., Russell, R.J., Steinhauer, D.A. (2008) Length Requirements for Membrane Fusion of Influenza Virus Hemagglutinin Peptide Linkers to Transmembrane or Fusion Peptide Domains {triangledown}. Journal of Virology; 82(13): 6337-6348..
Madine, J., Doig, AJ., Middleton, DA. (2008) Design of an N-Methylated Peptide Inhibitor of α-Synuclein Aggregation Guided by Solid-State NMR. Journal of the American Chemical Society; 130 (25), pp 7873-7881 DOI abs/10.1021.ja075356q.
Jacobsa, A., Garga, H., Viarda, M., Raviva, Y., Puria, A., Blumenthala, R. (2008) HIV-1 envelope glycoprotein-mediated fusion and pathogenesis: Implications for therapy and vaccine developmentstar. Vaccine; 26(24): 3026-3035..
Kasai, T., Tokuda, T., Yamaguchi, N., Watanabe, Y., Kametani, F., Nakagawa, M., Mizuno, T. (2008) Cleavage of normal and pathological forms of α-synuclein by neurosin in vitro. Neuroscience Letters; 436, 52-56.
Parihar, M.S., Parihar, A.,Fujita, M., Hashimoto, M., Ghafourifar, P. (2008) Mitochondrial association of alpha-synuclein causes oxidative stress. Journal of the Cellular and Molecular Life Sciences; 65(7-8): 1272-1284..
Wieneke J.A., Abdo, W.F., Melis, R., Williams, S., Bloem, B.R., Verbeek, M.M. (2008) A more efficient enzyme-linked immunosorbent assay for measurement of α-synuclein in cerebrospinal fluid. Journal of Neuroscience Methods; 168(1): 182-185..
Thoennesa, S., Lia, Z.N., Leea, B.J., Langleya, W.A., Skehelb, J.J., Russellc, R.J., Steinhauera, D.A. (2008) Analysis of residues near the fusion peptide in the influenza hemagglutinin structure for roles in triggering membrane fusion. Virology; 370(2): 403-414..
Ghosha, J.G., Houcka, S.A., Clarka, J.I. (2008) Interactive sequences in the molecular chaperone, human αB crystallin modulate the fibrillation of amyloidogenic proteins. The International Journal of Biochemistry & Cell Biology; 40(5): 954-967..
Wathen, B., Jia, Z. (2008) Local and Nonlocal Environments around Cis Peptides. J. Proteome Res; 7(01): 145-153..
Williamson, S.J.M (2008) Non-toxic concentrations of a-synuclein exacerbate Parkinson’s disease-like cell death by inducing mitochondrial dysfunction. The Universtiy of Edinburgh; 2008.
Leaman, Douglas W. (2008) Recent progress in oligonucleotide therapeutics: antisense to aptamers. Expert Opinion on Drug Discovery; 3(9): 997-1009..