Publications

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Beta Amyloid Citations: 2014

Silvia Maioli, Maria Lodeiro, Paula Merino-Serrais, Farshad Falahati, Wasim Khan, Elena Puerta, Alina Codita, Roberto Rimondini, Maria J. Ramirez, Andrew Simmons, Francisco Gil-Bea, Eric Westman, Angel Cedazo-Minguez1, and for the Alzheimer's Disease Neuroimaging Initiative (2014) Alterations in brain leptin signalling in spite of unchanged CSF leptin levels in Alzheimer's disease. Wiley Online Library; DOI: 10.1111/acel.12281.
William T. Hu, Kelly D. Watts, Leslie M. Shaw, Jennifer C. Howell, John Q. Trojanowski, Sundeep Basra, Jonathan D. Glass, James J. Lah and Allan I. Levey (2014) CSF beta-amyloid 1–42 – what are we measuring in Alzheimer's disease?. Wiley Online Library; DOI: 10.1002/acn3.160.
Zhongxiao Wan, Dorrian Mah, Svetlana Simtchouk, Andreas Kluftinger & Jonathan P Little (2014) Role of amyloid β in the induction of lipolysis and secretion of adipokines from human adipose tissue. Taylor Francis Online; DOI:10.4161/21623945.2014.985020.
Alexandra L Klinger, Janna Kiselar, Serguei Alekseyevich Ilchenko, Hiroaki Komatsu, Mark R. Chance, and Paul H Axelsen (2014) A Synchrotron-based Hydroxyl Radical Footprinting Analysis of Amyloid Fibrils and Pre-fibrillar Intermediates with Residue-specific Resolution. ACS Publications; DOI: 10.1021/bi5010409.
Ziao Fu, Darryl S. Aucoin, Mahiuddin Ahmed, Martine Ziliox, William E. Van Nostrand, and Steven O. Smith (2014) Capping of Aβ42 oligomers by small molecule inhibitors. ACS Publications; DOI: 10.1021/bi500910b.
Karine Bourgade, Hugo Garneau, Geneviève Giroux, Aurélie Y. Le Page, Christian Bocti, Gilles Dupuis, Eric H. Frost, Tamàs Fülöp Jr. (2014) β-Amyloid peptides display protective activity against the human Alzheimer’s disease-associated herpes simplex virus-1. Springer Link; DOI 10.1007/s10522-014-9538-8.
Kaleigh Filisa Roberts BS, Donald L. Elbert PhD, Tom P. Kasten PhD, Bruce W. Patterson PhD, Wendy C. Sigurdson RN, MSN, Rose E. Connors BS, Vitaliy Ovod MS, Ling Y. Munsell BS, Kwasi G. Mawuenyega PhD, Michelle M. Miller-Thomas MD, Christopher J. Moran MD, Dewitte T. Cross III MD, Colin P. Derdeyn MD, and Randall J. Bateman MD (2014) Amyloid-β efflux from the central nervous system into the plasma. Annals of Neurology; DOI: 10.1002/ana.24270.
Pietra Candela, Julien Saint-Pola, Marie-Christine Boucau, Fabien Gosselet, Laurence Fenart (2014) In vitro discrimination of the role of LRP1 at the BBB cellular level: Focus on brain capillary endothelial cells and brain pericytes. Science Direct; doi:10.1016/j.brainres.2014.10.047.
Daniel Paris, Ghania Ait-Ghezala, Corbin Bachmeier, Gary Laco, David Beaulieu-Abdelahad, Yong Lin, Chao Jin, Fiona Crawford and Michael Mullan (2014) The Spleen Tyrosine Kinase (syk) Regulates Alzheimer's Aβ Production and Tau Hyperphosphorylation. The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.608091.
Janice A. Maloney, Travis Bainbridge, Amy Gustafson, Shuo Zhang, Roxanne Kyauk, Pascal Steiner, Marcel van der Brug, Yichin Liu, James A. Ernst, Ryan J. Watts and Jasvinder K. Atwal (2014) Molecular Mechanisms of Alzheimer′s Disease Protection by the A673T Allele of Amyloid Precursor Protein. The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.589069.
Nitsch Maier, Andreas Plückthun and Roger M. Claudia Späni, Rebecca Derungs, Marcel Parizek, Lisa Strobel, Susann Cattepoel, Kulic, Tobias Welt, Fabian Wirth, Petra Michael Hanenberg, Jordan McAfoose, Luka (2014) Aβ-specific DARPins as a novel class of potential therapeutics for Alzheimer’s disease. The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.564013.
Linn Malmsten, Swetha Vijayaraghavan, Outi Hovatta, Amelia Marutle and Taher Darreh-Shori (2014) Fibrillar β-Amyloid 1-42 Alters Cytokine Secretion, Cholinergic Signalling and Neuronal Differentiation. Wiley Online Library; DOI: 10.1111/jcmm.12343.
Sergey V. Matveev, Hans Peter Spielmann, Brittney M. Metts, Jing Chen, Fredrick Onono, Haining Zhu, Stephen W. Scheff, Lary C. Walker, and Harry LeVine (2014) A distinct subfraction of Aβ is responsible for the high-affinity Pittsburgh compound B-binding site in Alzheimer's disease brain. Wiley Online Library; DOI: 10.1111/jnc.12815.
Nicolas L. Fawzi, David S. Libich, Jinfa Ying, Vitali Tugarinov, and G. Marius Clore (2014) Characterizing Methyl-Bearing Side Chain Contacts and Dynamics Mediating Amyloid-b Protofibril Interactions Using 13C methyl-DEST and Lifetime Line Broadening. NIH.gov; DOI: 10.1002/anie.201405180.
K. Ishara Silva, Brian C. Michael, Steven J. Geib, and Sunil Saxena (2014) ESEEM Analysis of Multi-Histidine Cu(II)-Coordination in Model Complexes, Peptides, and Amyloid-β. ACS Publications; DOI: 10.1021/jp500767n.
Nicola Acerra, Neil. M. Kad, Harish Cheruvara and Jody M. Mason (2014) Intracellular selection of peptide inhibitors that target disulphide-bridged Aβ42 oligomers. Wiley Online Library; 10.1002/pro.2509.
Cristina Airoldi, Spyridon Mourtas, Francisco Cardona, Cristiano Zona, Erika Sironi, Giuseppe D'Orazio, Eleni Markoutsa, Francesco Nicotra, Sophia G. Antimisiaris, Barbara La Ferla (2014) Nanoliposomes presenting on surface a cis-glycofused benzopyran compound display binding affinity and aggregation inhibition ability towards Amyloid β1-42 peptide. Science Direct; DOI: 10.1016/j.ejmech.2014.07.085.
Makoto Ishii, Gang Wang, Gianfranco Racchumi, Jonathan P. Dyke, and Costantino Iadecola (2014) Transgenic Mice Overexpressing Amyloid Precursor Protein Exhibit Early Metabolic Deficits and a Pathologically Low Leptin State Associated with Hypothalamic Dys. The Journal of Neuroscience; 10.1523/JNEUROSCI.0872-14.2014.
Kumi Nagamoto-Combsa, Joshua Kulasb, Colin K. Combs (2014) A novel cell line from spontaneously immortalized murine microglia. Science Direct; DOI: 10.1016/j.jneumeth.2014.05.021.
Megan Conway, Firoozeh Nafar, Tatjana Straka, Karen Mearow (2014) Modulation of Amyloid-β Protein Precursor Expression by HspB1. Metapress; DOI 10.3233/JAD-140348.
Josef Panneea, Ulrika Törnqvista, Anni Westerlunda, Martin Ingelssonb, Lars Lannfeltb, Gunnar Brinkmalma, Rita Perssona, Johan Goboma, Johan Svenssonc, Per Johanssonc, Henrik Zetterberga, Kaj Blennowa, Erik Porteliusa, (2014) The amyloid-β degradation pattern in plasma—A possible tool for clinical trials in Alzheimer's disease. Science Direct; 10.1016/j.neulet.2014.04.041.
Joseph J. Gingell, Erica R. Burns, and Debbie L. Hay (2014) Activity of Pramlintide, Rat and Human Amylin but not ABeta 1–42 at Human Amylin Receptors. pfizerpro.com; doi: 10.1210/en.2013-1658.
André Jerónimo-Santos, Sandra Henriques Vaz, Sara Parreira, Sofia Rapaz-Lérias, António P. Caetano, Valérie Buée-Scherrer, Eero Castrén, Claudia A. Valente, David Blum, Ana Maria Sebastião and Maria José Diógenes (2014) Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain. Oxford Journals; doi: 10.1093/cercor/bhu105.
Jason O. Matos, Greg Goldblatt, Jaekyun Jeon, Bo Chen, and Suren A. Tatulian (2014) Pyroglutamylated Amyloid-β Peptide Reverses Cross β-Sheets by a Prion-Like Mechanism. The Journal of Physical Chemistry; DOI: 10.1021/jp412743s.
Young G. Shin, Lee Hamm, Stanley Murakami, Kenji Buirst, Michael H. Buonarati, April Cox, Kelly Regal, Kevin W. Hunt, Kimberly Scearce-Levie, Ryan J. Watts, Xingrong Liu (2014) Qualification and application of a liquid chromatography–tandem mass spectrometric method for the determination of human Aβ1-40 and Aβ1-42 peptides in transgenic mouse plasma using micro-elution solid phase extraction. Springer Link; DOI 10.1007/s12272-013-0215-2.
Ryan T. Camerona, Steven D. Quinnb, Lynn S. Cairnsa, Ruth MacLeoda, Ifor D.W. Samuelb, Brian O. Smitha, J. Carlos Penedob, George S. Baillie (2014) The phosphorylation of Hsp20 enhances its association with amyloid-β to increase protection against neuronal cell death. Science Direct; http://dx.doi.org/10.1016/j.mcn.2014.05.002.
Rob J.A. Nabuursa, Varsha V. Kapoerchanb, Athanasios Metaxasc, Sanne de Jongha, Maaike de Backera, Mick M. Wellinga, Wim Jiskootd, Albert D. Windhorstc, Hermen S. Overkleeftb, Mark A. van Buchema, Mark Overhandb, Louise van der Weerda (2014) Polyfluorinated bis-styrylbenzenes as amyloid-β plaque binding ligands. Science Direct; DOI: 10.1016/j.bmc.2014.02.054.
Thomas McAvoy, Michael E. Lassman, Daniel S. Spellman, Zhenlian Ke, Bonnie J. Howell, Oitak Wong, Lan Zhu, Michael Tanen, Arie Struyk, Omar F. Laterza (2014) Quantification of Tau in Cerebrospinal Fluid by Immunoaffinity Enrichment and Tandem Mass Spectrometry. Clinical Chemistry; DOI: 10.1373/clinchem.2013.216515.
Nathaniel S. Woodling, Qian Wang, Prachi G. Priyam, Paul Larkin, Ju Shi, Jenny U. Johansson, Irene Zagol-Ikapitte, Olivier Boutaud, and Katrin I. Andreasson (2014) Suppression of Alzheimer-Associated Inflammation by Microglial Prostaglandin-E2 EP4 Receptor Signaling. The Journal of Neuroscience; doi: 10.1523/JNEUROSCI.0410-14.2014.
Francis T. Hanea, Brenda Y. Leea, Anahit Petoyanb, Arvi Raukb, Zoya Leonenko (2014) Testing synthetic amyloid-β aggregation inhibitor using single molecule atomic force spectroscopy. Science Direct; http://dx.doi.org/10.1016/j.bios.2013.10.060.
Peipei Wang, Wenfeng Liao, Jianping Fang, Qin Liu, Jian Yao, Minghua Hu, Kan Ding (2014) A glucan isolated from flowers of Lonicera japonica Thunb. inhibits aggregation and neurotoxicity of Aβ. Science Direct; DOI: 10.1016/j.carbpol.2014.03.060.
Orkid Coskuner, Ian V.J. Murray (2014) Adenosine Triphosphate (ATP) Reduces Amyloid-β Protein Misfolding in vitro. IOS Press; DOI: 10.3233/JAD-132300.
Irfan Y. Tamboli, Dongeun Heo, G. William Rebeck (2014) Extracellular Proteolysis of Apolipoprotein E (apoE) by Secreted Serine Neuronal Protease. PLOS One; DOI: 10.1371/journal.pone.0093120.
Saketh Chemuru, Ravindra Kodali and Ronald Wetzel (2014) Improved chemical synthesis of hydrophobic Aβ peptides using addition of C-terminal lysines later removed by carboxypeptidase B. Biopolymers; DOI: 10.1002/bip.22470.
Marta Tajes1, Abel Eraso-Pichot1, Fanny Rubio-Moscardó1, Biuse Guivernau1, Eva Ramos-Fernández1, Mònica Bosch-Morató1, Francesc Xavier Guix, Jordi Clarimón, Gian Pietro Miscione, Mercé Boada, Gabriel Gil-Gómez, Toshiharu Suzuki, Henrik Molina, Jordi Villà-Freixa, Rubén Vicente, Francisco J. Muñoz (2014) Methylglyoxal Produced by Amyloid-β Peptide-Induced Nitrotyrosination of Triosephosphate Isomerase Triggers Neuronal Death in Alzheimer's Disease. Metapress; DOI 10.3233/JAD-131685.
Pengcheng Hana, Zhiwei Tanga, Junxiang Yina, Marwan Maaloufa, Thomas G. Beachc, Eric M. Reimand, Jiong Shi (2014) Pituitary adenylate cyclase-activating polypeptide protects against β-amyloid toxicity. Science Direct; DOI: 10.1016/j.neurobiolaging.2014.03.022.
Scott Miners, Hayley Moulding, Rohan de Silva, andSeth Love (2014) Reduced Vascular Endothelial Growth Factor and Capillary Density in the Occipital Cortex in Dementia with Lewy Bodies. Brain Pathology; DOI: 10.1111/bpa.12130.
Nicola Acerra, Neil M. Kad, Douglas A. Griffith, Stanislav Ott, Damian C. Crowther, and Jody M. Mason (2014) Retro-inversal of Intracellular Selected β-Amyloid-Interacting Peptides: Implications for a Novel Alzheimer’s Disease Treatment. ACS Publications; DOI: 10.1021/bi5001257.
Jennifer Mayes, Claire Tinker-Mill, Oleg Kolosov, Hao Zhang, Brian J. Tabner, and Daivd Allsop (2014) β-Amyloid Fibrils in Alzheimer Disease Are Not Inert When Bound to Copper Ions but Can Degrade Hydrogen Peroxide and Generate Reactive Oxygen Species. The Journal of Biological Chemistry; 10.1074/jbc.M113.525212.
Walter Maetzler, Anja Apel, Markus Langkamp, Christian Deuschle, Sarah Selina Dilger, Johannes Georg Stirnkorb, Claudia Schulte, Erwin Schleicher, Thomas Gasser, Daniela Berg (2014) Comparable Autoantibody Serum Levels against Amyloid- and Inflammation-Associated Proteins in Parkinson’s Disease Patients and Controls. PLOS One; DOI: 10.1371/journal.pone.0088604.
Claire Tinker-Mill, Jennifer Mayes, David Allsop, & Oleg V. Kolosov (2014) Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation. Scientific Reports; doi:10.1038/srep04004.
Sandra D. Mulder, Henrietta M. Nielsen, Marinus A. Blankenstein, Piet Eikelenboom, and Robert Veerhuis (2014) Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microglia in vitro. Wiley Online Library; DOI: 10.1002/glia.22619.
Jacques Fantini, Coralie Di Scala, Nouara Yahi, Jean-Denis Troadec, Kevin Sadelli, Henri Chahinian, and Nicolas Garmy (2014) Bexarotene Blocks Calcium-Permeable Ion Channels Formed by Neurotoxic Alzheimer’s β-Amyloid Peptides. ACS Publications; DOI: 10.1021/cn400183w.
David G. Courtney1 , Sarah D. Atkinson1,2, Johnny E. Moore1 , Eleonora Maurizi3 , Chiara Serafini3 , Graziella Pellegrini3 , Graeme C. Black4,5, Forbes D. Manson4,5, Gary H. F. Yam6 , Edwin H. Allen1 , W. H. Irwin McLean2 and C. B. Tara Moore (2014) Development of allele specific gene silencing siRNAs for TGFBI Arg124Cys in Lattice Corneal Dystrophy Type I. Invest. Ophthalmol. Vis. Sci.; doi: 10.1167/iovs.13-13279.
Alexander Sandberg (2014) Interaction studies of luminescent conjugated oligothiophenes with aggregated Amyloid β. Diva-Portal; doi:10.1385/1-59259-890-0:571.
Eugene O'Hare, David I.C. Scopes, Eun-Mee Kim, Philip Palmer, David Spanswick, Bridgeen McMahon, Hozefa Amijee, Edmund Neroua, J. Mark Treherne and Ross Jeggo (2014) Novel 5-aryloxypyrimidine SEN1576 as a candidate for the treatment of Alzheimer's disease. Cambridge University Press; DOI: http://dx.doi.org/10.1017/S1461145713000886.
H Summersgill, H England, G Lopez-Castejon, C B Lawrence, N M Luheshi, J Pahle, P Mendes, and D Brough (2014) Zinc depletion regulates the processing and secretion of IL-1β. Nature.com; doi:10.1038/cddis.2013.547.