Publications

ORDER ONLINE  •  CALL 866.753.0747  •  FAX 678.753.0746

Beta Amyloid Citations: 2012

Di Scala C, Yahi N, Lelièvre C, Garmy N, Chahinian H, Fantini J. (2012) Biochemical Identification of a Linear Cholesterol-Binding Domain within Alzheimer’s β Amyloid Peptide. ACS Chem. Neurosci; December 27, 2012 DOI: 10.1021/cn300203a.
Liu Q, Huang Y, Shen J, Steffensen S, Wu J (2012) Functional alpha7beta2 nicotinic acetylcholine receptors expressed in hippocampal interneurons exhibit high sensitivity to pathological level of amyloid beta peptides. BMC Neuroscience; 29 December 2012, 13:155 doi:10.1186/1471-2202-13-155.
Kimura R, MacTavish D, Yang J, Westaway D, Jhamandas JH (2012) Beta Amyloid-Induced Depression of Hippocampal Long-Term Potentiation Is Mediated through the Amylin Receptor.. The Journal of Neuroscience,; 28 November 2012 32(48):17401-17406;doi:10.1523/JNEUROSCI.3028-12.2012.
Gibbs ME, Gibbs CL (2012) Deleterious Effects of Soluble Beta Amyloid on Cognition, Antagonisism by Saline and Noradrenaline, A Role for Microglia.. J.Neuroscience 17 November 2012; pii: S0306-4522(12)01099-8. doi: 10.1016/j.neuroscience.2012.10.070. [Epub ahead of print].
O'Hare E, Scopes DI, Kim EM, Palmer P, Jones M, Whyment AD, Spanswick D, Amijee H, Nerou E, McMahon B, Treherne JM, Jeggo R. (2012) Orally bioavailable small molecule drug protects memory in Alzheimer's disease models.. Neurobiol Aging. 2012 Nov 17; pii: S0197-4580(12)00527-1. doi: 10.1016/j.neurobiolaging.2012.10.016. [Epub ahead of print].
Robert Root-Bernstein and Abigail Podufaly (2012) T Cell Receptor Variable Regions in Di abetes Bind to Each Other, to Insulin, Glucagon or Insulin Rece ptor, and to Their Antibodies. The Open Autoimmunity Journal; 1876-8946/12.
Pannee J, Portelius E, Oppermann M, Atkins A, Hornshaw M, Zegers I, Höjrup P, Minthon L, Hansson O, Zetterberg H, Blennow K, Gobom J. (2012) A Selected Reaction Monitoring (SRM)-Based Method for Absolute Quantification of Aβ38, Aβ40, and Aβ42 in Cerebrospinal Fluid of Alzheimer's Disease Patients and Healthy Controls. J Alzheimer’s Dis; 2012 Oct 17. [Epub ahead of print] DOI 10.3233/JAD-2012-121471.
Tanifum EA, Dasgupta I, Srivastava M, Bhavane RC, Sun L, Berridge J, Pourgarzham H, Kamath R, Espinosa G, Cook SC, Eriksen JL, Annapragada A. (2012) Intravenous Delivery of Targeted Liposomes to Amyloid-β Pathology in APP/PSEN1 Transgenic Mice.. PLoS One. 2012;7(10):e48515; doi: 10.1371/journal.pone.0048515. Epub 2012 Oct 31..
Gunderson WA, Hernandez-Guzman J, Karr JW, Sun L, Szalai VA, Warncke K. (2012) Local Structure and Global Patterning of Cu2+ Binding in Fibrillar Amyloid-β [Aβ(1-40)] Protein. J. Am. Chem. Soc; Publication Date (Web): October 9, 2012 DOI: 10.1021/ja306946q.
Amijee H, Bate C, Williams A, Virdee J, Jeggo R, Spanswick D, Scopes DI, Treherne JM, Mazzitelli S, Chawner R, Eyers CE, Doig AJ. (2012) The N-Methylated Peptide SEN304 Powerfully Inhibits Aβ(1-42) Toxicity by Perturbing Oligomer Formation. Biochemistry; 2012 Oct 1. [Epub ahead of print].
Gan, Li (2012) Methods and Compositions for Modulating Tau Levels. United States Patent Application; United States Patent Application 20120225864. September 2012.
Vandersteen A, Masman MF, De Baets G, Jonckheere W, Van der Werf K, Marrink SJ, Rozenski J, Benilova I, De Strooper B, Subramaniam V, Schymkowitz J, Rousseau F, Broersen K. (2012) Molecular plasticity regulates oligomerization and cytotoxicity of the multi-peptide length Aβ pool. J. Biol. Chem; doi: 10.1074/jbc.M112.394635, PMID: 22992745.
Kroth H, Ansaloni A, Varisco Y, Jan A, Sreenivasachary N, Rezaei-Ghaleh N, Giriens V, Lohmann S, Lopez-Deber MP, Adolfsson O, Pihlgren M, Paganetti P, Froestl W, Nagel-Steger L, Willbold D, Schrader T, Zweckstetter M, Pfeifer A, Lashuel HA, Muhs A. (2012) Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formation.. J. Biol. Chem; 2012 Aug 13: doi:10.1074/jbc.M112.357665jbc.M112.357665.
Yam G.H.F., Wang K., Jhanji V., Choy K.W., Baum L., Pang C.P. (2012) In Vitro Amyloid Aggregate Forming Ability of TGFBI Mutants that Cause Corneal Dystrophies. Invest Ophthalmol Vis Sci.; 2012 Jul 31. [Epub ahead of print] doi: 10.1167/iovs.11-9068.
Klooster R., Rutgers K.S., van der Maarel S. M. (2012) Selection of VHH Antibody Fragments That Recognize Different Aβ Depositions Using Complex Immune Libraries. Methods in Molecular Biology; 2012, Volume 911, Part 3, 241-253, DOI: 10.1007/978-1-61779-968-6_15.
Bachmeier C., Beaulieu-Abdelahad D., Crawford F., Mullan M., Paris D. (2012) Stimulation of the Retinoid X Receptor Facilitates Beta-Amyloid Clearance Across the Blood–Brain Barrier.. JOURNAL OF MOLECULAR NEUROSCIENCE; 2012, DOI: 10.1007/s12031-012-9866-6.
Prades,R., Guerrero, S., Araya, E., Molina, C., Salas, E., Zurita, E., Selva, J., Egea, G., López-Iglesias, C., Teixidó, M., Kogan, M.J., Giralt, E. (2012) Delivery of gold nanoparticles to the brain by conjugation with a peptide that recognizes the transferrin receptor. Biomaterials; 2012 Jul 13. doi: 10.1016/j.biomaterials.2012.06.063.
Jones, M.R., Service, E.L., Thompson, J.R., Wang, M.C.P., Kimsey,I.J., DeToma, A. S., Lim, M. H., Ramamoorthy, A., Storr, T. (2012) Dual-function Triazole-pyridine Derivatives as Inhibitors of Metal-induced Amyloid-β Aggregation. Metallomics; 2012, [Epub ahead of print] DOI: 10.1039/C2MT20113E.
Heneka MT, Kummer MP. (2012) Inhibitors of the Nitration of Amyloid Beta Peptides and Their Uses in the Diagnosis and Treatment of Alzheimer's Disease. United States Patent; Application 20120192294.
Ran, C., Moore, A. (2012) Methods and System for Detecting Soluble Amyloid-Beta. United States Patent; Application 20120183474. July 19, 2012.
Wang, C.C., Huang, H.B., Tsay, H.J., Shiao, M.S., Wu, W.J., Cheng, Y.C., Lin, T.H. (2012) Characterization of Aβ aggregation mechanism probed by congo red. J Biomol Struct Dyn; 2012 Jun;30(2):160-9. Pubmed ID :22702727.
Nabuurs, R.J.A., Rutgers, K.S., Welling, M.M., Metaxas, A. de Backer, M.E., Rotman, M., Bacskai, B.J., van Buchem, M.A., van der Maarel, S., van der Weerd, L. (2012) In Vivo Detection of Amyloid-β Deposits Using Heavy Chain Antibody Fragments in a Transgenic Mouse Model for Alzheimer's Disease. PLoS One; 2012;7(6):e38284. Epub 2012 Jun 4 PMID: 22675537.
Brouillette, J., Caillierez, R., Zommer, N., Alves-Pires, C., Benilova, I., Blum, D., Strooper, B.,Buée, L. (2012) Neurotoxicity and Memory Deficits Induced by Soluble Low-Molecular-Weight Amyloid-β1–42 Oligomers Are Revealed In Vivo by Using a Novel Animal Model. The Journal of Neuroscience; 6 June 2012, 32(23): 7852-7861; DOI: 10.1523/JNEUROSCI.5901-11.2012.
Tate B, Loureiro RB, McKee TD, Dumin JA, Zarayskiy V, Austin WF, Fuller NO, Hubbs JL, Shen R, Ives J, Jonker J, Bronk B. (2012) Novel, potent, and selective modulators of gamma secretase. Satori Pharmaceuticals, Inc.; Presentation at World Pharma Congress, Targeting Alzheimer’s Disease June 5-7, 2012, Philadelphia, PA.
Howells, C., Saar, K., Eaton, E., Ray, S., Palumaa, P., Shabala, L., Adlard, P.A., Bennett, W., West, A.K., Guillemin, G., Chung, R.S. (2012) Redox-active Cu(II)–Aβ causes substantial changes in axonal integrity in cultured cortical neurons in an oxidative-stress dependent manner. Experimental Neurology; Available online 9 June 2012 DOI 10.1016/j.expneurol.2012.06.002.
Picoua, RA, Schrumb, DP, Kuc, G, Cerquaa,RA ,Kheterpalc, I, Gilmana, SD. (2012) Separation and detection of individual Aβ aggregates by capillary electrophoresis with laser-induced fluorescence detection. Analytical Biochemistry; Volume 425, Issue 2, 15 June 2012, Pages 104–112 DOI: 10.1016/j.ab.2012.03.006.
Sancesario, G.M., Cencioni, M.T., Esposito, A., Brosellino, G., Nuccetelli, M., Martorana, A., Battistini, L., Sorge, R., Spalletta, G., Ferrazzoli, D., Bernardi, G., Bernardini, S., Sancesario, G. (2012) The Load of Amyloid-β Oligomers is Decreased in the Cerebrospinal Fluid of Alzheimer's Disease Patients. Journal of Alzheimer's Disease; Volume 31, Number 4, IN PRESS DOI 10.3233/JAD-2012-120211.
Corbin Bachmeier, Daniel Paris, David Beaulieu-Abdelahad, Benoit Mouzon, Michael Mullan, Fiona Crawford (2012) A Multifaceted Role for apoE in the Clearance of Beta-Amyloid across the Blood-Brain Barrier.. Neurodegenerative Dis; (DOI: 10.1159/000337231); 2012 May 8 PubMed ID 22572854.
Carnini A, Scott LOM, Ahrendt E, Proft J, Winkfein RJ, et al. (2012) Cell Line Specific Modulation of Extracellular Aβ42 by Hsp40.. PLoS ONE; PLoS ONE 7(5): e37755. (2012) doi:10.1371/journal.pone.0037755.
Stefansson, S., Adams, DL, and Tang, C. (2012) Common benzothiazole and benzoxazole fluorescent DNA intercalators for studying Alzheimer Αβ1–42 and prion amyloid peptides. Fuzbien Technology Institute; (2012) ; DOI: BioTechniques.com/rd..
Hong, HB (Daejeon, KR) (2012) Method for Detecting Beta-Amyloid Using Amino Acid Dimers. United States Electronics and Telecommunications Research Institute; 2012 May 3; DOI: y2012/0107835.html; United States Patent Application 20120107835.
Guix, F. X., Wahle, T., Vennekens, K., Snellinx, A., Chávez-Gutiérrez, L., Ill-Raga, G., Ramos-Fernandez, E., Guardia-Laguarta, C., Lleó, A., Arimon, M., Berezovska, O., Muñoz, F. J., Dotti, C. G. and De Strooper, B., (2012) Modification of -secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease.. EMBO Mol Med.; 2012 May 2; doi: 10.1002/emmm.201200243.
Kasaia, T., Tokuda,T., Taylor, M., Nakagawa, M., Allsop, D., (2012) Utilization of a multiple antigenic peptide as a calibration standard in the BAN50 single antibody sandwich ELISA for Aβ oligomers. Biochemical and Biophysical Research Communications; 2012 May 3 DOI:10.1016/j.bbr.2011.03.031.
Njie eG, Kantorovich S, Astary GW, Green C, Zheng T, et al. (2012) A Preclinical Assessment of Neural Stem Cells as Delivery Vehicles for Anti-Amyloid Therapeutics.. PLoS ONE; 7(4): e34097. 2012 Apr 4, doi:10.1371/journal.pone.0034097.
Fu, W., Ruangkittisakul, A., MacTavish, D., Shi, J.Y., Ballanyi , K.and Jhamandas, JH (2012) Amyloid beta (Aβ) peptide directly activates Amylin-3 receptor subtype by triggering multiple intracellular signaling pathways. The Journal of Biological Chemistry; 2012 Apr 12, doi: 10.1074/jbc.M111.331181.
Wang, G., Dinkins, M., He, Q., Zhu, G., Poirier, C., Campbell, A., Mayer-Proschel , M. and Bieberich, E. (2012) Astrocytes secrete exosomes enriched with pro-apoptotic ceramide and prostate apoptosis response 4 (PAR-4): a potential mechanism of apoptosis induction in Alzheimer's disease (AD).. The Journal of Biological Chemistry; 2012 April 24, doi: 10.1074/jbc.M112.340513.
de la Fuente, E., Adura, C., Kogan, M.J., Bollo, S. (2012) Carbon Nanotubes Electrochemistry Allows the In Situ Evaluation of the Effect of β-Sheet Breakers on the Aggregation Process of β-Amyloid. Electroanalysis; Volume 24, issue 4, pp 938-944, April 2012 DOI: 10.1002/elan.201100607.
Scheffler, K., Krohn, M., Dunkelmann, T., Stenzel, J., Miroux, B., Ibrahim, S., Halbach. O, Heinze,HJ, Walker, LC and Gsponer, JA, et al. (2012) Mitochondrial DNA polymorphisms specifically modify cerebral β-amyloid proteostasis. Acta Neuropathologica; 2012, DOI: 10.1007/s00401-012-0980-x..
Madampage, C., Tavassoly, O., Christensen, C., Kumari, M. and Lee, J.. (2012) Nanopore analysis: An emerging technique for studying the folding and misfolding of proteins.. Prion; 6:2, 1-9; April/May/June 2012; Landes Bioscience; doi.org/10.4161/pri.6.2.18665..
Christine Grienberger, Rochefort, NL, Adelsberger, H.,Henning, HA,Hill, DN, Reichwald, J., Staufenbiel, M.& Konnerth, A. (2012) Staged decline of neuronal function in vivo in an animal model of Alzheimer's disease. Nature Communications; Volume: 3, Article number: 774 2012 Apr 10.
Solomonov, I., Korkotian, E., Born, B., Feldman, Y., Bitler, A., Rahimi, F., Li, H., Bitan, G. and Sagi, I.. (2012) Zn2+-Aβ40 complexes form metastable quasi-spherical oligomers that are cytotoxic to cultured hippocampal neurons.. The Journal of Biological Chemistry; 2012 April 23; DOI: 10.1074/jbc.M112.344036..
Yu, W., Polepalli, J., Wagh, D., Rajadas, J., Malenka, R. and Lu, B. (2012) A critical role for the PAR-1/MARK-tau axis in mediating the toxic effects of Aβ on synapses and dendritic spines. Hum. Mol. Genet; (2012) 21 (6): 1384-1390. DOI: 10.1093/hmg/ddr576.
Moir, R, Tanzi, RE. (2012) Antimicrobial Compositions and Methods of Use Therefore. The General Hospital Corporation; 2012 Mar 8; United States Patent Application 20120058935; DOI: y2012/0058935.html.
Li, Q., Lebson, L, Lee, DC, Nash, K, Grimm, J, Rosenthal, A, Selenica, MB, Morgan, D and Gordon, MN. (2012) Chronological Age Impacts Immunotherapy and Monocyte Uptake Independent of Amyloid Load. Journal of Neuroimmune Pharmacology; Volume 7, Number 1 (2012), 202-214, DOI: 10.1007/s11481-011-9329-9..
He, X. , Park, HM , Hyung , S, DeToma, AS , Kim, C. , Ruotolo, BT and Lim, MH. (2012) Exploring the reactivity of flavonoid compounds with metal-associated amyloid-β species. Dalton Trans.; 2012, 41, 6558-6566; 2012 Mar 22 DOI: 10.1039/C2DT12207C..
Chuang J-Y, Lee C-W, Shih Y-H, Yang T, Yu L, et al. (2012) Interactions between Amyloid-β and Hemoglobin: Implications for Amyloid Plaque Formation in Alzheimer's Disease.. PLoS ONE; 2012 Mar 6; PLoS ONE 7(3): e33120. doi:10.1371/journal.pone.0033120.
Larvie, M.,Shoup, T,Wei-Chuan Chang, W,Chigweshe, L.,Hartshorn, K.,White, MR, Stahl,GL, Elmaleh,, DR and Takahashi, K. (2012) Mannose-Binding Lectin Binds to Amyloid β Protein and Modulates Inflammation. Journal of Biomedicine and Biotechnology; Volume 2012 (2012), Article ID 929803, 12 pages doi:10.1155/2012/929803.
Ono, K, Li, L, Takamura, Y, Yoshiike. Y, Zhu, L, Han, F, Mao, X, Ikeda, T, Takasaki, J, Nishijo, H, Takashima, A, Teplow, DB, Zagorski, MG and Yamada, M. (2012) Phenolic compounds prevent amyloid β-protein oligomerization and synaptic dysfunction by site specific binding. The Journal of Biological Chemistry; 2012 Mar 5; doi: 10.1074/jbc.M111.325456.
Watanabe, K., Ishikawa, C., Kuwahara, H., Sato, K., Komuro, S., Nakagawa, T., Nomura, N., Watanabe, S. and Yabuki, M. (2012) A new methodology for simultaneous quantification of total-Aβ, Aβx-38, Aβx-40, and Aβx-42 by column-switching LC/MS/MS. Analytical and Bioanalytical Chemistry; Volume 402, Number 6 (2012), 2033-2042, DOI: 10.1007/s00216-011-5648-1.
Zhai, J., Lee, T-H., Small, D.H., Aguilar, M-I. (2012) Characterization of Early Stage Intermediates in the Nucleation Phase of Aβ Aggregation. Biochemistry; 2012, 51 (6), pp 1070–1078 January 24, 2012 DOI: 10.1021/bi201871r.
Esposito, L A., Hudson, MF., Lake, T , Cummings, J, Weigele, M, Snow, AD (2012) Compounds, Compositions, and Methods for the Treatment of Beta-Amyloid Diseases and Synucleinopathies. United States Patent Application; United States Patent Application 20120035230; 2012 Feb 9; DOI: y2012/0035230.html.
Combs, RG, Roe, S., Ruble, DL. (2012) Control of Protein Glycosylation and Compositions and Methods Relating Thereto. United States Patent Application; Pfizer Inc . 2012 Feb 16 United States Patent Application 20120039908; DOI: y2012/0039908.html.
Caesar I, Jonson M, Nilsson KPR, Thor S, Hammarström P. (2012) Curcumin Promotes A-beta Fibrillation and Reduces Neurotoxicity in Transgenic Drosophila.. PLoS ONE; 7(2): e31424. 2012 Feb 13; doi:10.1371/journal.pone.0031424.
Pfeifer, A., Pihlgren, M. , Muhs, A., Watts, R. (2012) Methods of treating and monitoring disease with antibodies.. AC Immune S.A; Genentech, Inc.; 2012 Feb 28; United States Patent 8124353 DOI: 8124353.html..
Tillement, L. (2012) Mitochondria-targeted amyloid : relevance to neurotoxicity and Alzheimer's disease. Department of Biochemistry and Molecular & Cellular Biology; 2012 Feb 10; DOI: handle/10822/552852.
Schweitzer-Stenner, R., Uversky V. (2012) Protein and Peptide Folding, Misfolding, and Non-Folding. Wiley Series in Protein and Peptide Science John Wiley & Sons; Feb 8, 2012 ISBN 978-0-470-59169-7.
Pauwels, K. , Williams, T.,Morris, KL, Jonckheere, W., Vandersteen, A.,Kelly, G., Schymkowitz, J., Rousseau, F., Pastore, A., Serpell, L and Broersen, K. (2012) Structural Basis for Increased Toxicity of Pathological Aβ42:Aβ40 Ratios in Alzheimer Disease. The Journal of Biological Chemistry; 287, 5650-5660. 2012 Feb 17; doi: 10.1074/jbc.M111.264473..
Schweitzer-Stenner, R., Uversky, V. (2012) 13.2. Overexpression and Purification of Recombinant Aβ; Peptide Folding, Misfolding, and Nonfolding. Wiley Series in Protein and Peptide Science; John Wiley and Sons, Inc.; 2012. DOI: go/permissions..
Nilsson, KP, Lindgren, M. and Hammarström, P. (2012) A Pentameric Luminescent-Conjugated Oligothiophene for Optical Imaging of In Vitro-Formed Amyloid Fibrils and Protein Aggregates in Tissue Sections. Amyloid Proteins; Methods in Molecular Biology; 2012, Volume 849, Part 3, 425-434, DOI: 10.1007/978-1-61779-551-0_29..
Fawver, JN., Schall, H.E., Chapa, RDP., Zhu, X., Murry IVJ. (2012) Amyloid-β Metabolite Sensing: Biochemical Linking of Glycation Modification and Misfolding. Journal of Alzheimer's Disease; Volume 30, Number 1 / 2012; DOI: 10.3233/JAD-2012-112114.
Lee, CY, Tse, W., Smith, JD and Landreth, GE. (2012) Apolipoprotein E Promotes β-Amyloid Trafficking and Degradation by Modulating Microglial Cholesterol Levels. The Journal of Biological Chemistry; 2012 Jan 13, 287, 2032-2044. doi: 10.1074/jbc.M111.295451..
Youa,H., Tsutsuib,S., Hameeda, S., Kannanayakalb, TJ, Chena, L, Xiac, P., Engbersa, JD, Liptonc, SA, Stysb, PK, and Zamponi, GW (2012) Aβ neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-d-aspartate receptors. PNAS; 2012 Jan 31 vol. 109 no. 5 1737-1742 doi: 10.1073/pnas.1110789109.
Yi-Jiong Zhang, Jing-Ming Shi, Cai-Juan Bai, Han Wang, Hai-Yun Li, Yi Wu and Shang-Rong Ji (2012) Intra-membrane Oligomerization and Extra-membrane Oligomerization of Amyloid-β Peptide Are Competing Processes as a Result of Distinct Patterns of Motif Interplay. The Journal of Biological Chemistry; 287, 748-756. 2012 Jan 2 doi: 10.1074/jbc.M111.281295.
Paranjape, GS, Gouwens, LK, Osborn,DC, and Nichols, MR (2012) Isolated Amyloid-β(1–42) Protofibrils, But Not Isolated Fibrils, Are Robust Stimulators of Microglia. ACS Chem. Neurosci; 2012, 3 (4), pp 302–311 2012 Jan 9 DOI: 10.1021/cn2001238.
Cramer, PE. (2012) Nuclear Receptor Activation and Alzheimer's Disease Pathogenesis. Doctor of Philosophy, Case Western Reserve University, Neurosciences; (2012). DOI: rave.ohiolink.edu/etdc/view?acc_num=case1332962440.
Minami, SS, Su, B., Popat, K., Kauppinen, T., Pleiss, M, Zhou, Y, Ward, M.E, Floreancig, P., Mucke, L, Desai, T. and Gan, L. (2012) Selective targeting of microglia by quantum dots. Journal of Neuroinflammation; 9:22; 2012 Jan 24 doi:10.1186/1742-2094-9-22.
Soura, V., Stewart‑Parker, M., Williams, TL, Ratnayaka, A., Atherton, J., Gorringe, K., Tuffin,, J., Darwent, E., Rambaran, R.,Klein, W., Lacor, P., Staras, K., Thorpe, J. and Serpell, LC (2012) Visualization of co-localization in Aβ42-administered neuroblastoma cells reveals lysosome damage and autophagosome accumulation related to cell death. Biochem. J.; (2012) 441 (579–590) doi:10.1042/BJ20110749.