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Beta Amyloid Citations: 2010

Bachmeier, C., Mullan, M., Paris, D. (2010) Characterization and use of human brain microvascular endothelial cells to examine β-amyloid exchange in the blood-brain barrier. Cytotechnology; Volume 92, Number 6 (2010), 519- 529, DOI 10.1007/s10616-010-9313-x.
Darreh-Shori T, Forsberg A, Modiri N, Andreasen N, Blennow K, Kamil C, Ahmed H, Almkvist O, Långström B, Nordberg A. (2010) Differential levels of apolipoprotein E and butyrylcholinesterase show strong association with pathological signs of Alzheimer's disease in the brain in vivo. Neurobiol Aging; 2011 Dec;32(12):2320.e15-32. doi. 10.1016/j.neurobiolaging.2010.04.028.
Maheshwari M, Roberts JK, Desutter B, Duong KT, Tingling J, Fawver JN, Schall HE, Kahle M, Murray IV (2010) Hydralazine Modifies Aβ Fibril Formation and Prevents Modification by Lipids. Biochemistry; 2010 Dec 14;49(49):10371-80. DOI: 10.1021/bi101249p.
Komatsu H, Feingold-Link E, Sharp KA, Rastogi T, Axelsen PH. (2010) Intrinsic linear heterogeneity of amyloid β protein fibrils revealed by higher resolution mass-per-length determinations. Journal of Biological Chemistry; 2010 Dec 31; 285 (53) :41843-51. PubMed PMID:20940298; PubMed Central PMCID: PMC3009912.
Schwetye KE, Cirrito JR, Esparza TJ, Mac Donald CL, Holtzman DM, Brody DL. (2010) Traumatic brain injury reduces soluble extracellular amyloid-β in mice: a methodologically novel combined microdialysis-controlled cortical impact study. Neurobiol Dis; 2010 Dec; 40 (3) :555-64. PubMed PMID:20682338; PubMed Central PMCID: PMC2955836..
Wicklund L, Leão RN, Strömberg AM, Mousavi M, Hovatta O, Nordberg A, Marutle A. (2010) Β-amyloid 1-42 oligomers impair function of human embryonic stem cell-derived forebrain cholinergic neurons. PLoS ONE; 2010 Dec 17; 5 (12) :e15600. PubMed PMID:21179413; PubMed Central PMCID: PMC3003688.
Zheng Z, Sabirzhanov B, Keifer J. (2010) Oligomeric amyloidβ inhibits the proteolytic conversion of brain-derived neurotrophic factor (BDNF), AMPA receptor trafficking, and classical conditioning. Journal of Biological Chemistry; 2010 Nov 5; 285 (45) :34708-17. PubMed PMID:20807770; PubMed Central PMCID: PMC2966086.
Williams TL, Day IJ, Serpell LC. (2010) The effect of Alzheimer's Aβ aggregation state on the permeation of biomimetic lipid vesicles. Langmuir; 2010 Nov 16;26(22):17260-8 DOI: 10.1002/jssc.200900713.
Noormägi A, Gavrilova J, Smirnova J, Tõugu V, Palumaa P. (2010) Zn(II) ions co-secreted with insulin suppress inherent amyloidogenic properties of monomeric insulin. Biochem J; 2010 Sep 15;430(3):511-8 doi:10.1042/BJ20100627.
Zovo K, Helk E, Karafin A, Tõugu V, Palumaa P. (2010) Label-Free High-Throughput Screening Assay for Inhibitors of Alzheimer’s Amyloid-β Peptide Aggregation Based on MALDI MS. Anal. Chem; 2010, 82 (20), pp 8558–8565 DOI: 10.1021/ac101583q.
Kreutzmann, P., Wolf, G., Kupsch, K. (2010) Minocycline Recover MTT-Formazan Exocytosis Impaired By Amyloid Beta Peptide. Cellular and Molecular Neurobiology; Volume 30, number 7 (2010), 979-984, DOI 10.1007/s1057-010-9528-6.
Chern JH, Hsu PC, Wang LW, Tsay HJ, Kang IJ, Shie FS. (2010) Modulation of microglial immune responses by a novel thiourea derivative. Chem Biol Interact; 2010 Oct 6; 188 (1) :228-36. PubMed PMID:20637185.
Kuperstein I, Broersen K, Benilova I, Rozenski J, Jonckheere W, Debulpaep M, Vandersteen A, Segers-Nolten I, Van Der Werf K, Subramaniam V, Braeken D, Callewaert G, Bartic C, D'Hooge R, Martins IC, Rousseau F, Schymkowitz J, De Strooper B. (2010) Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio. EMBO J; 2010 Oct 6; 29 (19) :3408-20. PubMed PMID:20818335; PubMed Central PMCID: PMC2957213.
Martineau E, de Guzman JM, Rodionova L, Kong X, Mayer PM, Aman AM. (2010) Investigation of the noncovalent interactions between anti-amyloid agents and amyloid beta peptides by ESI-MS. J Am Soc Mass Spectrom; 2010 Sep; 21 (9) :1506-14. PubMed PMID:20580569.
Singh TD, Park SY, Bae JS, Yun Y, Bae YC, Park RW, Kim IS. (2010) MEGF10 functions as a receptor for the uptake of amyloid-β. FEBS Letters; 2010 Sep 24; 584 (18) :3936-42. PubMed PMID:20828568.
Lee JS, Park CB. (2010) Microfluidic dissociation and clearance of Alzheimer's beta-amyloid aggregates. Biomaterials; 2010 Sep; 31 (26) :6789-95. PubMed PMID:20542328.
Knowles JK, Rajadas J, Nguyen TV, Yang T, LeMieux MC, Vander Griend L, Ishikawa C, Massa SM, Wyss-Coray T, Longo FM. (2010) The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivo.. J Neurosci; 2009 Aug 26;29(34):10627-37. PubMed PMID: 19710315; PubMed Central PMCID: PMC2771439.
Nielsen HM, Mulder SD, Beliën JA, Musters RJ, Eikelenboom P, Veerhuis R. (2010) Astrocytic A beta 1-42 uptake is determined by A beta-aggregation state and the presence of amyloid-associated proteins. Glia; 2010 Aug; 58 (10) :1235-46. PubMed PMID:20544859.
Paris D, Ganey N, Banasiak M, Laporte V, Patel N, Mullan M, Murphy SF, Yee GT, Bachmeier C, Ganey C, Beaulieu-Abdelahad D, Mathura VS, Brem S, Mullan M. (2010) Impaired orthotopic glioma growth and vascularization in transgenic mouse models of Alzheimer's disease. J Neurosci; 2010 Aug 25; 30 (34) :11251-8. PubMed PMID:20739545; PubMed Central PMCID: PMC2935547.
Kågedal K, Kim WS, Appelqvist H, Chan S, Cheng D, Agholme L, Barnham K, McCann H, Halliday G, Garner B. (2010) Increased expression of the lysosomal cholesterol transporter NPC1 in Alzheimer's disease. Biochim Biophys Acta; 2010 Aug; 1801 (8) :831-8. PubMed PMID:20497909.
Wiberg H, Ek P, Pettersson FE, Lannfelt L, Emmer A, Roeraade J. (2010) Separation and characterization of aggregated species of amyloid-beta peptides. Analytical and Bioanalytical Chemistry; Volume 397, Number 6 (2010), 2357-2366, DOI: 10.1007/s00216-010-3839-9.
Bruce-Keller AJ, Gupta S, Parrino TE, Knight AG, Ebenezer PJ, Weidner AM, LeVine H 3rd, Keller JN, Markesbery WR (2010) NOX activity is increased in mild cognitive impairment. Antioxid Redox Signal; 2010 Jun 15;12(12):1371-82.
Lee do Y, Lee KS, Lee HJ, Kim do H, Noh YH, Yu K, Jung HY, Lee SH, Lee JY, Youn YC, Jeong Y, Kim DK, Lee WB, Kim SS. (2010) Activation of PERK signaling attenuates Abeta-mediated ER stress. PLoS ONE; 2010 May 5; 5 (5) :e10489. PubMed PMID:20463975; PubMed Central PMCID: PMC2864758.
Lecanu L, Tillement L, McCourty A, Rammouz G, Yao W, Greeson J, Papadopoulos V. (2010) Dimethyl-carbamic acid 2,3-Bis-Dimethylcarbamoyloxy-6-(4-Ethyl-Piperazine-1-Carbonyl)-phenyl ester: a novel multi-target therapeutic approach to neuroprotection. Med Chem; 2010 May 1; 6 (3) :123-40. PubMed PMID:20438444.
Yu C, Nwabuisi-Heath E, Laxton K, Ladu MJ. (2010) Endocytic pathways mediating oligomeric Abeta42 neurotoxicity. Mol Neurodegener; 2010 May 17; 5:19. PubMed PMID:20478062; PubMed Central PMCID: PMC2881055.
Jan A, Hartley DM, Lashuel HA (2010) Preparation and characterization of toxic Abeta aggregates for structural and functional studies in Alzheimer's disease research. Nat Protoc; 2010; 5 (6) :1186-209. PubMed PMID:20539293.
Hartz AM, Miller DS, Bauer B (2010) Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease. Mol Pharmacol; 2010 May; 77 (5) :715-23. PubMed PMID:20101004; PubMed Central PMCID: PMC2872973.
Agholme L, Lindström T, Kågedal K, Marcusson J, Hallbeck M. (2010) An in vitro model for neuroscience: differentiation of SH-SY5Y cells into cells with morphological and biochemical characteristics of mature neurons. J Alzheimers Dis; 2010; 20 (4) :1069-82. PubMed PMID:20413890.
Taylor M, Moore S, Mayes J, Parkin E, Beeg M, Canovi M, Gobbi M, Mann DM, Allsop D (2010) Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease. Biochemistry; 2010 Apr 20; 49 (15) :3261-72. PubMed PMID:20230062.
Li Y, Duffy KB, Ottinger MA, Ray B, Bailey JA, Holloway HW, Tweedie D, Perry T, Mattson MP, Kapogiannis D, Sambamurti K, Lahiri DK, Greig NH. (2010) GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease.. J Alzheimers Dis; 2010; 19 (4) :1205-19. PubMed PMID:20308787; PubMed Central PMCID: PMC2948479.
Narasingappa RB, Prahalad RK, Mannar SS, Sathyanarayana RT, Hanumanthappa BK, Jagannatha RK. (2010) Molecular studies on Abeta(42) induced genomic instability in aged rabbit brain. Neurochem Int; 2010 Apr; 56 (5) :655-62. PubMed PMID:20117159..
Candela P, Gosselet F, Saint-Pol J, Sevin E, Boucau MC, Boulanger E, Cecchelli R, Fenart L. (2010) Apical-to-Basolateral Transport of Amyloid-β Peptides through Blood-Brain Barrier Cells is Mediated by the Receptor for Advanced Glycation End-Products and is Restricted by P-Glycoprotein. Alzheimers Dis; 2011;23(4):763 DOI 10.3233/JAD-2010-100462.
Kerr ML, Gasperini R, Gibbs ME, Hou X, Shepherd CE, Strickland DK, Foa L, Lawen A, Small DH. (2010) Inhibition of Abeta aggregation and neurotoxicity by the 39-kDa receptor-associated protein. J Neurochem; 2010 Mar; 112 (5) :1199-209. PubMed PMID:20002523..
Ebenezer PJ, Weidner AM, LeVine H 3rd, Markesbery WR, Murphy MP, Zhang L, Dasuri K, Fernandez-Kim SO, Bruce-Keller AJ, Gavilán E, Keller JN. (2010) Neuron Specific Toxicity of Oligomeric Amyloid-β: Role for JUN-Kinase and Oxidative Stress. J Alzheimers Dis; Volume 22, Number 3 (2010), 839-848 DOI 10.3233/JAD-2010-101161.
Luheshi LM, Hoyer W, de Barros TP, van Dijk Härd I, Brorsson AC, Macao B, Persson C, Crowther DC, Lomas DA, Ståhl S, Dobson CM, Härd T. (2010) Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo. PLoS Biol; 2010 Mar 16; 8 (3) :e1000334. PubMed PMID:20305716; PubMed Central PMCID: PMC2838747..
Li QY, Gordon MN, Chackerian B, Alamed J, Ugen KE, Morgan D. (2010) Virus-like peptide vaccines against Abeta N-terminal or C-terminal domains reduce amyloid deposition in APP transgenic mice without addition of adjuvant. J Neuroimmune Pharmacol; 2010 Mar; 5 (1) :133-42. PubMed PMID:20066498.
Liu, S.J., Gasperini, R., Foa, L., Small, D.H. (2010) Amyloid-β decreases cell-surface AMPA receptors by increasing intracellular calcium and phosphorylation of GluR2. J Alzheimers Dis; 2010;21(2):655-66. DOI 10.3233/JAD-2010-09 1654.
Magparangalan DP, Garrett TJ, Drexler DM, Yost RA (2010) Analysis of large peptides by MALDI using a linear quadrupole ion trap with mass range extension. Anal Chem; 010 Feb 1; 82 (3) :930-4. PubMed PMID:20063857.
Ellis G, Fang E, Maheshwari M, Roltsch E, Holcomb L, Zimmer D, Martinez D, Murray IV. (2010) Lipid oxidation and modification of amyloid-β (Aβ) in vitro and in vivo. J Alzheimers Dis; 2010;22(2):593-607. DOI 10.3233/JAD-2010-100960.
Njie EG, Boelen E, Stassen FR, Steinbusch HW, Borchelt DR, Streit WJ. (2010) Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function. Neurobiol Aging; 2012 Jan;33(1):195.e1-12. DOI 10.1016/j.neurobiolaging.2010.05.008.
Kim WS, Bhatia S, Elliott DA, Agholme L, Kågedal K, McCann H, Halliday GM, Barnham KJ, Garner B. (2010) Increased ATP-binding cassette transporter A1 expression in Alzheimer's disease hippocampal neurons. J Alzheimers Dis; 2010 Jan; 21 (1) :193-205. PubMed PMID:20413849.
Hou X, Small DH, Aguilar MI. (2010) Surface plasmon resonance spectroscopy in determination of the interactions between amyloid beta proteins (Abeta) and lipid membranes. Methods Mol Biol; 2010; 627:225-35. PubMed PMID:20217625.