Alpha-Synuclein, Monkey, Desalted
Recombinant. A DNA sequence encoding the monkey alpha-synuclein, was expressed in E. coli.
Alpha-Synuclein (a-Synuclein) is a 14 kD (140 amino acids) acidic presynaptic protein. It is a major component of Parkinson's disease aggregates and is implicated in the pathogenesis of Parkinson's Disease and related neurodegenerative disorders. a-Synuclein accumulates in the brains of sporadic Parkinson's disease patients as a major component of Lewy bodies, which are intraneuronal cytoplasmic inclusions characteristic of Parkinson's disease. a-Synuclein appears to associate with other proteins that aggregate and is found in B-amyloid plaques and neuritic tangles in Alzheimer's disease3. Monkey alpha-Synuclein has a 98% homologous sequence to Human Alpha-Synuclein. This product is supplied in a buffer without salt to better fill the needs of customers whose experiments may have interference with NaCl.
14.47kDa by Mass Spec. Analysis (14.47kDa theoretical)
>95% by SDS-PAGE and Mass Spec.