Beta-Synuclein

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Product Name
Beta-Synuclein
Size
Catalog #
S-1003-1
Storage
-20°C
Sequence
MDVFMKGLSM AKEGVVAAAE KTKQGVTEAA EKTKEGVLYV GSKTREGVVQ GVASVAEKTK EQASHLGGAV FSGAGNIAAA TGLVKREEFP TDLKPEEVAQ EAAEEPLIEP LMEPEGESYE DPPQEEYQEY EPEA
Source
Recombinant. A DNA sequence encoding the human beta-synuclein sequence was expressed in E. coli.
Description
Beta-Synuclein (β-synuclein, 134 amino acids) co-localizes with α- synuclein in some brain regions but unlike α-synuclein it is not found in Lewy bodies of Parkinson’s disease. It has been shown to inhibit the self aggregation of α-synuclein 1.
Molecular Mass
14,288 Da
Purity
>95% by SDS-PAGE and Mass Spec.
Cost (US$)
$300
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1) Hashimoto, M. et al. (2001) Neuron, 32: 213
2) Jakes, R. et al. (1994) FEBS Letters, 345: 27