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Chemokine CXCL-12 (SDF1-α)

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Product Name
Chemokine CXCL-12 (SDF1-α)
Catalog #
Chemokines attract immune cells to sites of inflammation.1 In addition, chemokine signaling recruits neurons and other cells to specific sites during metastasis. The most conserved chemokine ligand/receptor signaling pathway is CXCL12/CXCR4/CXCR7.2 Therefore, the receptor CXCL12 has been produced as a new product at rPeptide and represents chemokines in the study of neurodegenerative diseases. Since chemokines have a role in inflammatory cell attraction, the function of neuroprotection in Alzheimer’s disease is an active area of investigation.
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1) Oppenheim JJ, Zachariae CO, Mukaida N, Matsushima K. Properties of the novel proinflammatory supergene "intercrine" cytokine family. Annu Rev Immunol. 1991;9:617-648

2) DeVries ME, Kelvin AA, Xu L, Ran L, Robinson J, Kelvin DJ. Defining the origins and evolution of the chemokine/chemokine receptor system. J Immunol. 2006;176(1):401-415.