Beta-Amyloid Precursor Protein, CTF-57

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Product Name
Beta-Amyloid Precursor Protein, CTF-57
Size
250 µg
Catalog #
A-1203-1
Storage
-20°C
Sequence
T V I V I T L V M L K K K Q Y T S I H H G V V E V D A A V T P E E R H L S K M Q Q N G Y E N P T Y K F F E Q M Q N
Source
Synthetic peptide.
Description
The 57-amino acid peptide results from the gama-secretase cleavage of the C-terminus of beta-amyloid precursor protein (APP) at Ala713-Thr714. This is also naturally generated in conjunction with Abeta,1-42. May also serve as one of the precursors for the generation of the toxic C31, fragment of APP (Cat. No. A-1201) in vivo.
Molecular Mass
6650.7 Da
Purity
>95%
Cost (US$)
$205
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Temporarily Unavailable
1) Gu, Y., et al. (2001) J. Biol. Chem, 276: 35235
2) Pinnix, I., et al. (2001). J. Biol. Chem, 276: 481
3) Yu, C., et al. (2001) J. Biol. Chem 276: 43756.