Beta-Amyloid Precursor Protein, CTF-31

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Product Name
Beta-Amyloid Precursor Protein, CTF-31
Size
250 µg
Catalog #
A-1201-1
Storage
-20°C
Sequence
A A V T P E E R H L S K M Q Q N G Y E N P T Y K F F E Q M Q N
Source
Synthetic peptide.
Description
The 31-amino acid peptide results from the proteolytic cleavage of the C- terminus of beta-amyloid precursor protein (APP) at Asp739-Ala740 by caspases. Potentially involved in the neuronal death associated with Alzheimer’s disease, either via amplifying caspase activation or by the selective increase in Abeta1-42 production.
Molecular Mass
3717.1
Purity
>95%
Cost (US$)
$130
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Temporarily Unavailable
1) Dumanchin-Njock, C., et al. (2001) J. Neurochem, 78: 1153
2) Soriano, S., et al. (2001) J. Biol. Chem, 276: 29045
3) Gervais, F.G., et al. (1999) Cell, 97: 395
4) LeBlanc, A., et al. (1999) J. Biol. Chem, 274: 23426.