Myeloperoxidase

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Product Name
Myeloperoxidase
Size
100 µg
Catalog #
A-2007-1
Storage
–20°C
Description
Myeloperoxidase (MPO) was found to be a key oxidant-producing enzyme during inflammation and it appeared to be upregulated in the ventral midbrain of human PD. It has been suggested that inhibitors of MPO "may provide a protective benefit in PD" 1. Although unexpected, myeloperoxidase expression was found in neurons and it increased in brain tissue showing AD neuropathology. Thus it is possible that MPO contributes to the oxidative stress implicated in the pathogenesis of the neurodegenerative disorder.
Molecular Mass
150,000 kDa
Purity
>=95% by SDS-PAGE
Cost (US$)
$75
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1) Choi, D-K, et al., (2005), The J. Neuroscience, 25(28):6594-6600.
2) Green, PS, (2004), J. Neurochemistry, 90(3): 724 -733.