Chymotrypsin

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Product Name
Chymotrypsin
Size
100 µg
Catalog #
A-2005-1
Storage
–20°C
Source
Human Pancreas
Description
Chymotrypsin-like proteasome activities were found to increase in cells treated with 10-100 uM 6-OHDA, while "higher doses caused a marked decline" 1 Such harsh oxidative attacks might cause failure of the ubiquitin-proteasome system (UPS) which leads to protein aggregation and cell death. "Mutations in familial PD have been associated with the failure of protein degradation through UPS".
Molecular Mass
25,000 kDa
Purity
>=95% by SDS-PAGE
Cost (US$)
$150
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1) Elkon, H. et al., (2004), J. Molecular Neuroscience 24(3):387-400.