C16

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Product Name
C16
Size
Catalog #
N-3030-2
Storage
-20°C
Description
Inhibits RNA-dependent protein kinase (PKR, IC50 = 210 nM)1. Inhibits ER stress-induced neuronal damage2. Reduces brain PKR activation in vivo3. Prevents apoptosis and IL-1 Beta production in an acute excitotoxic and neuroinflammatory rat model4. Prevents Beta-amyloid peptide-induced inflammation in primary murine mixed co-cultures5. Cell permeable.
Molecular Mass
268.3
Purity
>98%
Cost (US$)
$240
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1.NV Jammi et al. Biochem. Biophys. Res. Commun. 2003 308:50
2.M Shimazawa et al. Neurosci. Lett. 2006 409:192
3.S Ingrand et al. FEBS Lett. 2007 581:4473
4.C Tronel et al. Neurochem. Int. 2014 64:73
5.J Couturier et al. J. Neuroinflammation 2011 8:72