Montelukast Sodium

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Product Name
Montelukast Sodium
Size
Catalog #
N-3028-1
Storage
-20°C
Description
Potent, selective CysLT1 receptor (leukotriene D4) antagonist (Ki = 0.18 nM)1,2. Displays anti-inflammatory and anti-asthmatic effects. Clinically useful agent for treatment of chronic asthma3. Attenuates chronic brain injury after focal cerebral ischemia in rodent models4. Decreases blood brain barrier dysfunction in mouse models5. Blockade of GPR17 by montelukast elevates neural stem and progenitor proliferation6.
Molecular Mass
608.2
Purity
>98%
Cost (US$)
$60
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1.KR Lynch et al. Nature 1999 399:789
2.TR Jones et al. Can. J. Physiol. Pharmacol. 1995 73:191
3.TF Reiss et al. Arch. Intern. Med. 1998 158:1213
4.R Zhao et al. J. Pharm. Pharmacol. 2011 63:550
5.QF Lenz et al. Neuroscience 2014 26:277
6.C Huber et al. Cell Physiol. Biochem. 2011 28:793