Diazoxide

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Product Name
Diazoxide
Size
Catalog #
N-3026-2
Storage
-20°C
Description
Activates ATP-dependent K+ channels1 via inducing translocation of PKC-epsilon from the cytosol to the mitochondria2. Hyperglycemic agent. Induces powerful protective effects against cardiac ischemia via multiple mechanisms3. Stimulates mitochondrial ATP synthase activity conferring cardioprotection in a streptozotocin-induced acute diabetes model4. Prevents alterations in memory and synaptic plasticity induced by Amyloid-Beta5.
Molecular Mass
230.7
Purity
>98%
Cost (US$)
$120
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1.G Trube et al. Pflugers Arch. 1986 407:493
2.MY Kim et al. Br. J. Pharmacol. 2006 149:1059
3.WA Coetzee et al. Pharmacol. Ther. 2013 140:167
4.M Jasova et al. Physiol. Res. 2016 65 Suppl 1:S119
5.K Salgado-Puga et al. J. Alzheimers Dis. 2017 57:205