Fingolimod

ORDER ONLINE  •  CALL 866.753.0747  •  FAX 678.753.0746

Product Name
Fingolimod
Size
Catalog #
N-3025-2
Storage
-20°C
Description
An analog of sphingosine which, when taken up into cells, is phosphorylated and acts as an agonist at sphingosine-1-phosphate receptors (S1P1/3)1. Potently inhibits regulatory T cell proliferation in vitro and in vivo2. Enhances microvascular remodeling via expansion of arterioles and capillary networks3. Potent immunomodulatory4. Clinically effective agent for relapsing forms of multiple sclerosis5.
Molecular Mass
343.9
Purity
>98%
Cost (US$)
$160
Place an Order
Quantity

Would you like 10 or more?  Save on cost by requesting a Large Quantity Quote.

1. V Brinkmann et al. J. Biol. Chem. 2002 277:21453
2. AM Wolf et al. J. Immunol. 2009 183:3751
3. AO Awojoodu et al. Proc. Natl. Acad. Sci. USA 2013 110:13785
4. K Chiba Pharmacol. Ther. 2005 108:308
5. T Ziemssen et al. J. Neurol. 2016 263:1053