Vorinostat

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Product Name
Vorinostat
Size
Catalog #
N-3021-1
Storage
-20°C
Description
Potent and selective histone deacetylase inhibitor1. Induces apoptosis in a variety of tumor cell lines (IC50 = 3-8 μM)2. Synergizes with kinase inhibitors to kill CNS tumor cells3. Prevents diabetes in a mouse model by immunoregulation and -cell protection4. Induces neuronal differentiation in DKFZ-EP1NS cells, a cell line which displays stem cell features such as self-renewal capacity5. Cell permeable.
Molecular Mass
264.3
Purity
>98%
Cost (US$)
$50
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Quantity

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1. JA Vrana et al. Oncogene 1999 18:7016
2. LM Butler et al. Proc. Natl. Acad. Sci. USA 2002 99:11700
3. Y Tang et al. Cancer Biol. Ther. 2012 13:567
4. DP Christensen et al. Proc. Natl. Acad. Sci. USA 2014 111:1055
5. T Milde et al. Acta. Neuropathol. 2011 122:637