Tianeptine

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Product Name
Tianeptine
Size
Catalog #
N-3008-1
Storage
-20°C
Description
Selective enhancer of serotonin uptake in the brain with no effect on noradrenalin or dopamine uptake. Clinically useful antidepressant2. Displays neuroprotective effects against hypoxia in cell culture and against the deleterious effects of cytokines in vivo3. Induces mTORC1 activation in rat hippocampal neurons and increases dendritic outgrowth, spine density and synaptic proteins4. Attenuates LPS-evoked inflammatory activation of microglial cells in culture5.
Molecular Mass
458.9
Purity
>98%
Cost (US$)
$40
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1.T Mennini et al. Naunyn-Schmied. Arch. Pharmacol. 1987 336:478
2.G Kato and AF Weitsch Clin. Neuropharmacol. 1988 11:S43
3.F Plaisant et al. Neuropharmacology 2003 44:801
4.MK Seo et al. Psychopharmacology (Berl.) 2016 233:2617
5.J Slusarcyk et al. J. Neurochem. 2017 136:958