LM22A-4

ORDER ONLINE  •  CALL 866.753.0747  •  FAX 678.753.0746

Product Name
LM22A-4
Size
Catalog #
N-3006-2
Storage
-20°C
Description
Small molecule BDNF mimetic displaying neurotrophic activity. Partial agonist at TrkB and activates TrkB signaling. In in vitro models of neurodegenerative disease, it prevented neuronal degeneration with equal efficacy to that of BDNF. After in vivo administration, it caused hippocampal and striatal TrkB activation in mice and improved motor learning after traumatic brain injury in rats1. Improves respiratory function in a mouse model of Rett syndrome2.
Molecular Mass
339.3
Purity
>98%
Cost (US$)
$480
Place an Order
Quantity

Would you like 10 or more?  Save on cost by requesting a Large Quantity Quote.

1. SM Massa et al. J. Clin. Invest. 2010 120:1774
2. DA Schmid et al. J. Neurosci. 2012 32:1803