LM11A-31 2HCI

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Product Name
LM11A-31 2HCI
Size
Catalog #
N-3005-2
Storage
-20°C
Description
A nonpeptide neurotrophic factor receptor p75 (p75NTR) agonist which promotes survival signaling in neurotrophin-responsive cells1. Promotes functional recovery in a mouse model of spinal contusion injury2. Protects neurogenesis after traumatic brain injury3. Reverses cholinergic neurite dystrophy in Alzheimer’s disease mouse models4. Stabilizes neuronal calcium, preserves mitochondrial movement and protects against HIV-associated neuropathogenesis5. Orally active and blood-brain barrier permeant.
Molecular Mass
316.3
Purity
>98%
Cost (US$)
$192
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Quantity

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1.SM Massa et al. J. Neurosci. 2006 26:5288
2.C Tep et al. J. Neurosci. 2013 33:397
3.J Shi et al. Stem Cells 2013 31:2561
4.DA Simmons et al. PLoS One 2014 9(8):e102136
5.RB Meeker et al. Exp. Neurol. 2016 275 Pt1:182