C-646

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Product Name
C-646
Size
Catalog #
N-3002-2
Storage
-20°C
Description
Potent and selective inhibitor of the histone acetyl transferase p300/CBP (Ki=400 nM )1. Induces apoptosis in prostate cancer cells2. Enhances fear extinction memory and synaptic plasticity in mice3. Promotes tau deacetylation reducing levels of pathogenic p-tau4. Cell permeable.
Molecular Mass
445.4
Purity
>98%
Cost (US$)
$320
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Quantity

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1. EM Bowers et al. Chem. Biol. 2010 17:471
2. FR Santer et al. Mol. Cancer Ther. 2011 10:1644
3. R Marek et al. J. Neurosci. 2011 31:7486
4. S-W Min et al. Neuron 2010 67:953