Ferrostatin-1

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Product Name
Ferrostatin-1
Size
Catalog #
N-1380-2
Storage
-20°C
Description
Inhibits ferroptosis (EC50060 nM), an iron-dependent form of nonapoptotic cell death1. Potent inhibitor of ferroptosis in cancer cells and glutamate-induced cell death in organotypic rat brain slices1. Blocks the cytotoxic effects of sorafenib in hepatocellular carcinoma cells2. Inhibits oxidative lipid damage and cell death in diverse disease models3. Prevents apoptosis of renal proximal tubular cells induced by reactive oxygen species4. Mitigates rotenone-induced alpha-synuclein aggregation in SHSY-5Y cells5.
Purity
>98%
Cost (US$)
$160
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Quantity

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1. SJ Dixon et al. Cell 2012 149:1060
2. C Louandre et al. Int. J. Cancer 2013 133:1732
3. R Skouta et al. J. Am. Chem. Soc. 2014 136:4551
4. G Nowak et al. Am. J. Physiol. Renal. Physiol. 2013 305:F764
5. P Kabiraj et al. Protein J. 2015 34:349