Alpha Synuclein 10C3 Antibody

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Product Name
Alpha Synuclein 10C3 Antibody
Size
Catalog #
SA-3001-2
Storage
-20°C
Source
Mouse
Description
Alpha-Synuclein (α-Synuclein) is a 14 kD (140 amino acids) acidic presynaptic protein. It is a major component of Parkinson’s disease aggregates and is implicated in the pathogenesis of Parkinson’s Disease and related neurodegenerative disorders. α-Synuclein accumulates in the brains of sporadic Parkinson’s disease patients as a major component of Lewy bodies, which are intraneuronal cytoplasmic inclusions characteristic of Parkinson’s disease. α-Synuclein appears to associate with other proteins that aggregate and is found in β-amyloid plaques and neuritic tangles in Alzheimer’s disease3. Alpha Synuclein 10C3 is a monoclonal antibody that is specific for human alpha synuclein. 10C3 has been shown to work within ELISA, Western Blot, as well as Immunhistochemistry experiments.
Purity
>95%
Cost (US$)
$2,800
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Quantity

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1) Conway, K.A. et. al., (2000) Biochemistry, 39: 2552
2) Jakes, R. et al. (1994), FEBS Letters, 345: 27
3) Masliah, E. et. al., (2001) Proc. Natl. Acad. Sci., USA, 98: 12245
4)Ueda, K., et. al. (1993) Proc. Natl. Acad. Sci., USA, 90: 11282