Beta-Amyloid (1-42), Ultra Pure, NH4OH

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Product Name
Beta-Amyloid (1-42), Ultra Pure, NH4OH
Size
Catalog #
A-1167-02
Storage
-20°C
Sequence
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Source
Recombinant. A DNA sequence encoding the human beta-amyloid (1-42) sequence was expressed in E. coli.
Description
Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer's patients, is thought to be the cause of Alzheimer's Disease (AD)1-3. AD is the most common neurodegenerative disease and afflicts about 10% of the population over 60 4. Using a proprietary production technique that limits the peptide's conformational changes, rPeptide has produced an ammonium hydroxide beta amyloid counter-ion. The Abeta ammonium hydroxide product can be utilized for in vitro aggregation experiments as well as cell based assays.
Molecular Mass
4514.1 Da
Purity
>97%
Cost (US$)
$118
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Quantity

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1) Yankner, BA, et. al., (1990) Science, 250: 279-282
2) Selkoe, D.J., (2001) Physiol. Rev, 81: 741-766
3) Stine, W.B. et. al., (2003) J. Biol. Chem, 278: 11612-11622
4) Frank, R.A., et. al., (2003) Neurobiology of Aging, 24: 521-536