Beta-Amyloid (11-42)

ORDER ONLINE  •  CALL 866.753.0747  •  FAX 678.753.0746

Product Name
Beta-Amyloid (11-42)
Size
1.0 mg
Catalog #
A-1063-2
Storage
-20°C
Sequence
E V H H Q K L V F F A E D V G S N K G A I I G L M V G G V V I A
Source
Recombinant. A DNA sequence encoding the human beta-amyloid (11-42) sequence was expressed in E. Coli.
Description
Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer�s patients, is thought to be the cause of Alzheimer�s Disease (AD). Alzheimer�s diseased brains show significant levels of Abeta (11-40) and Abeta (11-42). The �-secretase enzyme or �- amyloid precursor protein-cleaving enzyme (BACE) generates the N terminus of A�, producing full-length Abeta (1- 40 and 1-42) and/or truncated Abeta (11-40 and 11-42). The abundance of Abeta (11-40 and 11-42) produced by BACE suggests that they might be playing an important role in Alzheimer�s disease pathogenesis.
Molecular Mass
3151.7 Da
Purity
>97%
Cost (US$)
$325
Place an Order
Quantity

Would you like 10 or more?  Save on cost by requesting a Large Quantity Quote.

1) Liu K, et al., (2002) Biochemistry, 41:3128-36.