C-646
Potent and selective inhibitor of the histone acetyl transferase p300/CBP (Ki=400 nM ) 1. Induces apoptosis in prostate cancer cells 2. Enhances fear extinction memory and synaptic plasticity in mice 3. Promotes tau deacetylation reducing levels of pathogenic p-tau 4. Cell permeable.
$608.00
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Product Details
- Size: 25.0mg
- Physical State: Orange powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Molecular Mass: 445.4
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References
1. Bowers, E.M., et al., (2010) Chem. Biol., 17 : 471
2. Santer, F.R., et al., (2011) Mol. Cancer Ther., 10 : 1644
3. Marek, R., et al., (2011) J. Neurosci., 31 : 7486
4. Min, S.W., et al., (2010) Neuron, 67 : 953
