Description:The plasmin system is involved in the degradation of Abeta peptides1. Brain plasmin enhances APP alpha-cleavage and Abeta degradation and is reduced in Alzheimer's disease brains1,2.
References:1. Shibata, N., et. al., (2006), Neurobiol Aging. Jul 5, PMID: 16828203. 2. Ledesma, MD, et. al., (2000), EMBO Rep. Dec;1(6):530-5.