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64,000kDa AD patients seem to express increased alpha 1-Antichymotrypsin (AACT) index, suggesting an intrathecal production of AACT. Indeed, AACT is a major component of the amyloid plaques found in the brains of AD patients. In Parkinson's disease (PD), AACT gene has been suggested as a susceptibility factor that might be related to the onset of PD1, 2.
1. Pirttila T., et al., (1994) Neurobiology of Aging. May-Jun; 15(3):313-7.
2. Haines J.L., et al., Genomics, 1996 April; 33(1):53-56(4).
Catalog No: A-2002-1 Quantity: 100 ug Price: $60
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