Murray, I.V.J., Liu, L., Komatsu, H., Uryu, K., Xiao, G., Lawson, J.A., Axelsen, P.H. (2007) Membrane mediated amyloidogenesis and the promotion of oxidative lipid damage by amyloid β proteins. Journal of Biological Chemistry; 282(13):9335–9345
Garzon, D.J., Fahnestock, M. (2007) Oligomeric amyloid decreases basal levels of brain–derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human neuroblastoma cells. The Journal of Neuroscience; 27(10):2628–2635.
Yan, Y., Wang, C. (2007) Aβ40 protects non–toxic Aβ42 monomer from aggregation. Journal of Molecular Biology; 369:909–916.
Chen, L., Jin, J., Davis, J., Zhou, Y., Wang, Y., Liu, J., Lockhart, P.J., Zhang, J. (2007) Oligomeric α–synuclein inhibits tubulin polymerization.Biochemical and Biophysical ResearchCommunications; 356:548–553.
Garai, K., Sureka, R., Maiti, S. (2007) Detecting amyloid–β aggregation with fiber–based fluorescence correlation spectroscopy. Biophysical Journal; 92:L55–L57.
Lacor, P.N., Buniel, M.C., Furlow, P.W., Clemente, A.S., Velasco, P.T., Wood, M, Viola, K.L., Klein, W.L. (2007) Aβ oligomer–induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in alzheimer's disease. Neurobiology of Disease; 27(4):796–807.
De–Felice, F.G., Velasco, P.T., Lambert, M.P., Viola, K., Fernandez, S.J., Ferreira, S.T., Klein, W.L. (2007) Aβ oligomers induce neuronal oxidative stress through an N–methyl–D–aspartate receptor–dependent mechanism that is blocked by the alzheimer drug memantine. The Journal of Biological Chemistry; 282(15):11590–11601.
Scott Kim, W., Rahmanto, A.S., Kamili, A., Rye, K–A., Guillemin, G.J., Gelissen, I.C., Jessup, W., Hill, A.F., Garner, B. (2007) Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid–β peptide generation. The Journal of Biological Chemistry; 282(5):2851–2861.
Du, P., Wood, K.M., Rosner, M.H., Cunningham, D., Tate, B., Geoghegan, K.F. (2007) Dominance of amyloid precursor protein sequence over host cell secretases in determining β–amyloid profiles studies of interspecies variation and drug action by internally standardized immunoprecipitation/mass spectrometry. The Journal of Pharmacology and Experimental Therapeutics; 320(3):1144–1152.
Johansson, A–S., Garlind, A., Berglind–Dehlin, F., Karlsson, G., Edwards, K., Gellerfors, P., Ekholm–Pettersson, F., Palmblad, J., Lannfelt, L. (2007) Docosahexaenoic acid stabilizes soluble amyloid–β protofibrils and sustains amyloid–β–induced neurotoxicity in vitro. The FEBS Journal; 274: 990–1000.
Hu, M., Schurdak, M.E., Puttfarcken, P.S., Kouhen, R.E., Gopalakrishnan, M., Li, J. (2007) High content screen microscopy analysis of Aβ1–42–induced neurite outgrowth reduction in rat primary cortical neurons: Neuroprotective effects of α7 neuronal nicotinic acetylcholine receptor ligands. Brain Research; 1151:227–235.
Danielsson, J., Pierattelli, R., Banci, L., Graslund, A. (2007) High–resolution NMR studies of the zinc–binding site of the Alzheimer's amyloid β–peptide. The FEBS Journal; 274:46–59.
Bharathi. Rao , K.S.J. (2007) Thermodynamics imprinting reveals deferential binding of metals to α–synuclein: Relevance to parkinson's disease: Biochemical and Biophysical Research Communications; 359:15–120.
Suram, A., Hegde, M.L., Rao, K.S.J. (2007) A new evidence for DNA nicking property of amyloid β–peptide (1–42): Relevance to Alzheimer's disease. Archives of Biochemistry and Biophysics; (In press).
Hegde, M.L., Rao, K.S.J. (2007) DNA induces folding in a–synuclein: Understanding the mechanism using chaperone property of osmolytes. Archives of Biochemistry and Biophysics; (In press).
Jin, J., Shie, F–S., Liu, J.,Wang,Y., Davis, J., Schantz, A.M., Montine, K.S., Montine, T.H., Zhang, J. (2007) Prostaglandin E2 receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated α–synuclein. Journal of Neuroinflammation; 4:2 doi: 10.1186/1742–2094–4–2.
Pym, J.L., Buckingham, D.S., Tsetlin, V., Boyd, C.A.R., Sattelle, D.B.S. (2007) The Aβ1–42M35C mutated amyloid peptide Aβ1–42 and the 25–35 fragment fail to mimic the subtype–specificity of actions on recombinant human nicotinic acetylcholine receptors (α7, α4β2, α3β4). Neuroscience Letters; 427(1):28–33.
Chen, L., Jin, J., Davis J., Zhou, Y., Wang, Y., Liu, J., Lockhart, P.J., and Zhag, J. (2007) Oligomeric α–synuclein inhibits tubulin polymerization. Biochemical and Biophysical Research Communications; 356(3):548–553.
Yan, Y., Liu, J., McCallum, S.A., Yang, D., Wang, C. (2007) Methyl dynamics of the amyloid–β peptides Aβ40 and Aβ42. Biochemical and Biophysical Research Communications; 362(2):410–414.
20. Diana, K., Gabriele, J., Markus, G., Markus, K., Mathias, J., Igor, M., Ingolf, Lary C.W., Heyo, K.K., Rolf, W.W., Silke, V. (2007) MDR1–P–Glycoprotein (ABCB1) Mediates Transport of Alzheimer’s Amyloid–β Peptides–Implications for the Mechanisms of Aβ Clearance at the Blood–Brain Barrier. Brain Pathology; 17(4):347–353.
Sahoo, B., Goswami, M., Nag, S., Maiti, S. (2007) Spontaneous formation of a protein corona prevents the loss of quantum dot fluorescence in physiological buffers. Chemical Physics Letters; 445(4–6):217–220.
Klegeris, A., McGeer, P.L. (2007) Complement activation by islet amyloid polypeptide (IAPP) and α–synuclein 112. Biochemical and Biophysical Research Communications; 357(4):1096–1099.
Wieneke J.A Van Geel., Abdo, W., F.,Melis, R., Williams, S., Verbeek, M., M. (2007) A more efficient enzyme–linked immunosorbent assay for measurement of α–synuclein in cerebrospinal fluid. Journal of Neuroscience Methods , Article in Press, Corrected Proof.
Englund. H., Sehlin.D., Johansson. A–S., Nilsson. L. N.G., Gellerfors. P., Pettersson. F.E. (2007) Sensitive ELISA detection of amyloid–β protofibrils in biological samples. Journal of Neurochemistry; 103(1):334–345.
Manelli. A.M., Bulfinch. L.C., Sullivan. P.M., LaDu. M.J. (2007) Aβ42 neurotoxicity in primary co–cultures: Effect of apoE isoform and Aβ conformation. Neurobiology of Aging; 28(8):1139–1147.
Boddaert. J., Kinugawa. K., Lambert. J–C., Boukhtouche. F., Zoll. J., Olivier. B–B., Mann. D., Berr. C., Vilar. J., Garabedian. B., Charue. D., Duyckaerts. C., Amouyel. P., Mariani. J., Tedgui. A., Mallat. Z. (2007) Evidence of a Role for Lactadherin in Alzheimer's Disease. American Journal of Pathology; 170:921–929.
Udan. M.L.D., Ajit. D., Crouse. N.R., Nicholas. M.R. (2007) Toll–like receptors 2 and 4 mediate Aβ(1–42) activation of the innate immune response in a human monocytic cell line. Journal of Neurochemistry; 104(2):524–533.
Findeis. M.A. (2007) The role of amyloid β peptide 42 in Alzheimer’s disease. Pharmacology & Therapeutics; 116(2):266–286.
Bell. R.D., Sagare. A.P., Friedman. A.E., Bedi. G.S., Holtzman. D.M., Deane. R., Zlokovic.B.V. (2007) Transport pathways for clearance of human Alzheimer’s amyloid β–peptide and apolipoproteins E and J in the mouse central nervous system. Journal of Cerebral Blood Flow & Metabolism; 27: 909–918.
Walker, D.G., Link, J., Lue, L–F., Dalsing–Hernandez, J.E., Boyes, B. E. (2006) Gene expression changes by amyloid β peptide–stimulated human postmortem brain microglia identify activation of multiple inflammatory processes. Journal of Leukocyte Biology; 79:596–610.
Inoue, K., Garner, C., Ackermann, B.L., Oe, T., Blair, I. A. (2006) Liquid chromatography/tandem mass spectrometry characterization of oxidized amyloid beta peptides as potential biomarkers of Alzheimer's disease. Rapid Commun. Mass Spectrometry; 20(5):911–918.
Craft, J.M., Watterson, D.M., Eldik, L.J.V. (2006) Human amyloid β–induced neuroinflammation is an early event in neurodegeneration. Glia; 53:484–490.
Floden, A.M., Combs, C.K., (2006) β–Amyloid Stimulates Murine Postnatal and Adult Microglia Cultures in a Unique Manner. Journal of Neuroscience; 26(17):4644–4648.
Simard, A.R., Soulet, D., Gowing, G., Julien, J–P., Rivest, S. (2006) Bone marrow–derived microglia play a critical role in restricting senile plaque formation in Alzheimer's diseases. Neuron; 49: 489–502.
Johansson, A–S., Berglind–Dehlin, F., Karlsson, G., Edwards, K., Gellerfors, P., Lannfelt, L. (2006) Physiochemical characterization of the Alzheimer’s disease–related peptides Aβ1–42Arctic and Aβ1–42wt. The FEBS Journal; 273(12):2618–2630.
Bagriantsev, S., Liebman, S. (2006) Modulation of Aβ42 low–n oligomerization using a novel yeast reporter system. BMC Biology; 4:32.
Isaacs, A.M., Senn, D.B., Yuan, M., Shine, J.P., Yankner, B.A. (2006) Acceleration of amyloid β–peptide aggregation by physiological concentrations of calcium. Journal Biological Chemistry; 281(38):27916–27923.
Moses, G.S., Jensen, M.D., Lue, L–F., Walker, D.G., Sun, A.Y., Simonyi, A., Sun, G.Y. (2006) Secretory PLA2–IIA: a new inflammatory factor for Alzheimer’s disease. Journal of Neuroinflammation; 3:28.
Ingelsson, M., Ramasamy, K., Cantuti–Castelvetri, I., Skoglund, L., Matsui, T., Orne, J., Kowa, H., Raju, S., Vanderburg, C.R., Augustinack, J.C., Silva, R.D., Lees, A.J., Lannfelt, L., Growdon, J.H., Frosch, M.P., Standaert, D.G., Irizarry, M.C., Hyman, B.T. (2006) No alteration in tau exon 10 alternative splicing in tangle–bearing neurons of the Alzheimer's disease brain. Acta Neuropathol; 112:439–449.
Williamson, M.P., Suzuki, Y., Bourne, N.T., Asakura, T. (2006) Binding of amyloid β to ganglioside micelles is dependent on histidine–13. Biochemical Journal; 397:483–490.
Sun, Z.P., Alpa, C., Yuan, J.M., Reinhard, S–S., Wei, Y. (2006) A novel method to study aggregation of amyloid β1–42 – A key peptide associated with Alzheimer’s disease. Abstracts of Papers, 231st ACS National Meeting, Atlanta, GA, United States, March 26–30, 2006, INOR–128. CODEN: 69HYEC AN2006: 247457 CAPLUS.
Oe, T., Ackermann, B.L., Inoue, K., Berna, M.J., Garner, C.O., Gelfanova, V., Dean, R.A., Siemers, E.R., Holtzman, D.M., Farlow, M.R., Blair, I.A. (2006) Quantitative analysis of amyloid β peptides in cerebrospinal fluid of Alzheimer’s disease patients by immunoaffinity purification and stable isotope dilution liquid chromatography–negative electrospray ionization/ tandem mass spectrometry. Rapid Communications in Mass Spectrometry; 20:3723–3735
Mueller–Steiner, S., Zhou, Y., Arai, H., Roberson, E.D., Sun, B., Chen, J., Wang, X., Yu, G., Esposito, L., Mucke, L., Gan, L. (2006) Antiamyloidogenic and neuroprotective Functions of cathepsin B: implications for alzheimer's disease. Neuron; 51:703–714.
Lue, L– F., Yan, S.D., Stern, D.M., Walker, D.G. (2005) Preventing activation of receptor for advanced glycation endproducts in Alzheimer’s disease. Current Drug Targets – CNS & Neurological Disorders; 4(3):249–266.
Nichols, M.R., Moss, M.A., Reed, D.K., Cratic–McDaniel, S., Hoh, J.H., Rosenberry, T.L. (2005) Amyloid–β protofibrils differ from amyloid–β aggregates induced in dilute hexafluoroisopropanol in stability and morphology. Journal Biological Chemistry; 280(4):2471–2480.
Dickey, C.A., Gordon, M.N., Wilcock, D.M., Herber, D.L., Freeman, M.J., Morgan, D. (2005) Dysregulation of Na+/K+ ATPase by amyloid in APP+PS1 transgenic mice. BMC Neuroscience; 6:7.
Unlap, M.T., Williams, C., Morin, D., Siroky, B., Fintha, A., Fuson, A., Dodgen, L., Kovacs, G., Komlosi, P., Ferguson, W., Bell, P.D. (2005) Amyloid beta peptide 1–40 stimulates the Na+ / Ca2+ exchange activity of SNCX. Current Neurovascular Research; 2(1):3–12.
Chen, J., Zhou, Y., Mueller–Steiner, S., Chen, L–F., Kwon, H., Yi, S., Mucke, L., Gan, L. (2005) SIRT1 protects against microglia–dependent amyloid–β toxicity through inhibiting NF–?B signaling. Journal Biological Chemistry; 280(48):40364–40374.
Shie, F–S., Breyer, R.M., Montine, T.J. (2005) Microglia lacking E prostanoid receptor subtype 2 have enhanced Aβ phagocytosis yet lack Aβ–activated neurotoxicity. American Journal of Pathology; 166(4):1163–1172.
Shie, F–S., Montine, K.S., Breyer, R.M., Montine T.J. (2005) Microglial EP2 is critical to neurotoxicity from activated cerebral innate immunity. Glia; 52:70–76.
Lindberg, C., Crisby, M., Winblad, B., Schultzberg, M. (2005) Effects of statins on microglia. Journal of Neuroscience Research; 82:10–19.
Wiley, J.C., Hudson, M., Kanning, K.C., Schecterson, L.C., Bothwell, M. (2005) Familial Alzheimer’s disease mutations inhibit ?–secretase–mediated liberation of β–amyloid precursor protein carboxy–terminal fragment. Journal of Neurochemistry; 94(5):1189–1201.
Nichols, M.R., Moss, M.A., Reed, D.K., Hoh, J.H., Rosenberry, T.L. (2005) Amyloid–β aggregates formed at polar–nonpolar interfaces differ from amyloid–β protofibrils produced in aqueous buffers. Microscopy Research and Technique; 67:164–174.
Hu, Q., Wang, L., Yang, Z., Cool, B.H., Zitnik, G., Martin, G.M. (2005) Endoproteolytic cleavage of FE65 converts the adaptor protein to a potent suppressor of the sAPPα pathway in primates. Journal Biological Chemistry; 280(13):12548–12558.
Medina, M.G., Ledesma, M.D., Domínguez, J.E., Medina, M., Zafra, D., Alameda, F., Dotti, C.G., Navarro, P. (2005) Tissue plasminogen activator mediates amyloid–induced neurotoxicity via Erk1/2 activation. The EMBO Journal; 24(9):1706–1716.
Park, L., Anrather, J., Zhou, P., Frys, K., Pitstick, R., Younkin, S., Carlson, G.A., Iadecola, C. (2005) NADPH oxidase–derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid β peptide. The Journal of Neuroscience; 25(7):1769–1777.
Lindberg, C., Selenica, M–L. B., Westlind–Danielsson, A., Schultzberg, M. (2005) β–Amyloid protein structure determines the nature of cytokine release from rat microglia. Journal Molecular Neuroscience; 27:1–12.
Murray, I.V., Sindoni, M.E., Axelsen, P.H. (2005) Promotion of oxidative lipid membrane damage by amyloid β proteins. Biochemistry; 44:12606–12613.
Ciccotosto, G.D., Tew, D., Curtain, C.C., Smith, D., Carrington, D., Masters, C.L., Bush, A.I., Cherny, R.A., Cappai, R., Barnham, K.J. (2004) Enhanced Toxicity and Cellular Binding of a Modified Amyloid Peptide with a methionine to valine substitution. Journal Biological Chemistry; 279: 42528–42534.
Hou, L., Shao, H., Zhang, Y., Li, H., Menon, N.K., Neuhaus, E.B., Brewer, J.M., Byeon, I.L., Ray, D.G., Vitek, M.P., Iwashita, T., Makula, R.A., Przybyla, A.B., Zagorski, M.G. (2004) Solution NMR studies of the Aβ(1–40) and Aβ(1–42) peptides establish that the Met35 oxidation state affects the mechanism of amyloid formation. J. Am. Chem. Soc; 126:1992–2005.
Mandal, P.K., Pettegrew, J.W., (2004) Alzheimer's disease: NMR studies of asialo (GMI) and trisialo (GT1b) ganglioside interactions with Aβ(1–40) peptide in a membrane mimic environment. Neurochemical Research; 29(2):447–453.
El–Agnaf, O.M.A., Paleologou, K.E., Greer, B., Abogrein, A.M., King, J.E., Salem, S.A., Fullwood, N.J., Benson, F.E., Hewitt, R., Ford, K.J., Martin, F.L., Harriott, P., Cookson, M.R., Allsop, D. (2004) A strategy for designing inhibitors of alpha–synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders. The Faseb Journal; June 4, doi:10.1096/fj.03–1346fje.
Barnham, K.J., Haeffner, F., Ciccotosto, G.D., Curtain, C.C., Tew, D., Mavros, C., Beyreuther, K., Carrington, D., Masters, C.L., Cherny, R.A., Cappai, R., Bush, A.I. (2004) Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer’s disease β–amyloid. The Faseb Journal; July 1, doi:10.1096/fj.03–1346fje.
Wu, J., Kuo, Y–P., George, A.A., Xu, L., Hu, J., Lukas, R.J. (2004) β–amyloid directly inhibits human α4β2–nicotinic acetylcholine receptors heterologously expressed in human SH–EP1 cells. Journal of Biological Chemistry; 279(36):37842–37851.
Stine, W.B. Jr, Dahlgren, K.N., Krafft, G.K., and LaDu, M.J. (2003) In vitro characterization of conditions for amyloid–β peptide oligomerization and fibrillogenesis. Journal Biological Chemistry; 278:11612–11622.
LeVine III, H. (2003) Y10W b (1–40) fluorescence reflects epitope exposure in conformers of Alzheimer's β peptide. Archives of Biochem and Biophys; 417(1):112–122.
Dahlgren, K. N., Manelli, A. M., Stine, W. B. J., Baker, L. K., Krafft, G. A., and LaDu, M. J. (2002) Oligomeric and fibrillar species of amyloid–β peptides differentially affect neuronal viability. J. Biol. Chem; 277:32046–32053.
Zeng, H., Zhang, Y., Peng, L.–J, Shao, H., Menon, N.K., Yang, J., Salomon, A.R., Friedland, R.P. and Zagorski, M.G. (2001) Nicotine and amyloid formation. Biological Psychiatry; 49:&c 248–257.
Chesneau, V., Vekrellis, K., Rosner, M.R., and Selkoe, D. (2000) Purified recombinant insulin–degrading enzyme degrades amyloid b protein but does not promote its oligomerization. Biochem. Journal; 351:509–516.
Gordon R, Hogan CE, Neal ML, Anantharam V, Kanthasamy AG, Kanthasamy A. A simple magnetic separation method for high-yield isolation of pure primary microglia. J Neurosci Methods. 2011 Jan 15; 194 (2) :287-96. PubMed PMID:21074565.
Komatsu H, Feingold-Link E, Sharp KA, Rastogi T, Axelsen PH. Intrinsic linear heterogeneity of amyloid {beta} protein fibrils revealed by higher resolution mass-per-length determinations. J Biol Chem. 2010 Dec 31; 285 (53) :41843-51. PubMed PMID:20940298; PubMed Central PMCID: PMC3009912.
Wicklund L, Leão RN, Strömberg AM, Mousavi M, Hovatta O, Nordberg A, Marutle A. Β-amyloid 1-42 oligomers impair function of human embryonic stem cell-derived forebrain cholinergic neurons. PLoS One. 2010 Dec 17; 5 (12) :e15600. PubMed PMID:21179413; PubMed Central PMCID: PMC3003688.
Op De Beéck K, Van den Bergh K, Vermeire S, Decock S, Derua R, Waelkens E, Rutgeerts P, Nevens F, Bossuyt X. Immune reactivity to {beta}-tubulin isotype 5 and vesicular integral-membrane protein 36 in patients with autoimmune gastrointestinal disorders. Gut. 2010 Dec 15; PubMed PMID:21159894.
Hane F, Drolle E, Leonenko Z. Effect of cholesterol and amyloid-β peptide on structure and function of mixed-lipid films and pulmonary surfactant BLES: an atomic force microscopy study. Nanomedicine. 2010 Dec; 6 (6) :808-14. PubMed PMID:20493966.
Schwetye KE, Cirrito JR, Esparza TJ, Mac Donald CL, Holtzman DM, Brody DL. Traumatic brain injury reduces soluble extracellular amyloid-β in mice: a methodologically novel combined microdialysis-controlled cortical impact study. Neurobiol Dis. 2010 Dec; 40 (3) :555-64. PubMed PMID:20682338; PubMed Central PMCID: PMC2955836.
Zheng Z, Sabirzhanov B, Keifer J. Oligomeric amyloid-{beta} inhibits the proteolytic conversion of brain-derived neurotrophic factor (BDNF), AMPA receptor trafficking, and classical conditioning. J Biol Chem. 2010 Nov 5; 285 (45) :34708-17. PubMed PMID:20807770; PubMed Central PMCID: PMC2966086.
Mata IF, Shi M, Agarwal P, Chung KA, Edwards KL, Factor SA, Galasko DR, Ginghina C, Griffith A, Higgins DS, Kay DM, Kim H, Leverenz JB, Quinn JF, Roberts JW, Samii A, Snapinn KW, Tsuang DW, Yearout D, Zhang J, Payami H, Zabetian CP. SNCA variant associated with Parkinson disease and plasma alpha-synuclein level. Arch Neurol. 2010 Nov; 67 (11) :1350-6. PubMed PMID:21060011; PubMed Central PMCID: PMC3010848.
Spicakova T, O'Brien MM, Duran GE, Sweet-Cordero A, Sikic BI. Expression and silencing of the microtubule-associated protein Tau in breast cancer cells. Mol Cancer Ther. 2010 Nov; 9 (11) :2970-81. PubMed PMID:21062914.
Mougenot AL, Bétemps D, Hogeveen KN, Kovacs GG, Chouaf-Lakhdar L, Milhavet O, Lehmann S, Legastelois S, Pin JJ, Baron TG. Production of a monoclonal antibody, against human α-synuclein, in a subpopulation of C57BL/6J mice, presenting a deletion of the α-synuclein locus. J Neurosci Methods. 2010 Oct 15; 192 (2) :268-76. PubMed PMID:20709102.
Kuperstein I, Broersen K, Benilova I, Rozenski J, Jonckheere W, Debulpaep M, Vandersteen A, Segers-Nolten I, Van Der Werf K, Subramaniam V, Braeken D, Callewaert G, Bartic C, D'Hooge R, Martins IC, Rousseau F, Schymkowitz J, De Strooper B. Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio. EMBO J. 2010 Oct 6; 29 (19) :3408-20. PubMed PMID:20818335; PubMed Central PMCID: PMC2957213.
Chern JH, Hsu PC, Wang LW, Tsay HJ, Kang IJ, Shie FS. Modulation of microglial immune responses by a novel thiourea derivative. Chem Biol Interact. 2010 Oct 6; 188 (1) :228-36. PubMed PMID:20637185.
Dragusanu M, Petre BA, Slamnoiu S, Vlad C, Tu T, Przybylski M. On-line bioaffinity-electrospray mass spectrometry for simultaneous detection, identification, and quantification of protein-ligand interactions. J Am Soc Mass Spectrom. 2010 Oct; 21 (10) :1643-8. PubMed PMID:20692851.
Eroglu B, Moskophidis D, Mivechi NF. Loss of Hsp110 leads to age-dependent tau hyperphosphorylation and early accumulation of insoluble amyloid beta. Mol Cell Biol. 2010 Oct; 30 (19) :4626-43. PubMed PMID:20679486; PubMed Central PMCID: PMC2950521.
Singh TD, Park SY, Bae JS, Yun Y, Bae YC, Park RW, Kim IS. MEGF10 functions as a receptor for the uptake of amyloid-β. FEBS Lett. 2010 Sep 24; 584 (18) :3936-42. PubMed PMID:20828568.
Lee JS, Park CB. Microfluidic dissociation and clearance of Alzheimer's beta-amyloid aggregates. Biomaterials. 2010 Sep; 31 (26) :6789-95. PubMed PMID:20542328.
Martineau E, de Guzman JM, Rodionova L, Kong X, Mayer PM, Aman AM. Investigation of the noncovalent interactions between anti-amyloid agents and amyloid beta peptides by ESI-MS. J Am Soc Mass Spectrom. 2010 Sep; 21 (9) :1506-14. PubMed PMID:20580569.
Cheung MC, Vaisar T, Han X, Heinecke JW, Albers JJ. Phospholipid transfer protein in human plasma associates with proteins linked to immunity and inflammation. Biochemistry. 2010 Aug 31; 49 (34) :7314-22. PubMed PMID:20666409; PubMed Central PMCID: PMC2930196.
Paris D, Ganey N, Banasiak M, Laporte V, Patel N, Mullan M, Murphy SF, Yee GT, Bachmeier C, Ganey C, Beaulieu-Abdelahad D, Mathura VS, Brem S, Mullan M. Impaired orthotopic glioma growth and vascularization in transgenic mouse models of Alzheimer's disease. J Neurosci. 2010 Aug 25; 30 (34) :11251-8. PubMed PMID:20739545; PubMed Central PMCID: PMC2935547.
Padmaraju V, Indi SS, Rao KS. New evidences on Tau-DNA interactions and relevance to neurodegeneration. Neurochem Int. 2010 Aug; 57 (1) :51-7. PubMed PMID:20435075.
Nielsen HM, Mulder SD, Beliën JA, Musters RJ, Eikelenboom P, Veerhuis R. Astrocytic A beta 1-42 uptake is determined by A beta-aggregation state and the presence of amyloid-associated proteins. Glia. 2010 Aug; 58 (10) :1235-46. PubMed PMID:20544859.
Kågedal K, Kim WS, Appelqvist H, Chan S, Cheng D, Agholme L, Barnham K, McCann H, Halliday G, Garner B. Increased expression of the lysosomal cholesterol transporter NPC1 in Alzheimer's disease. Biochim Biophys Acta. 2010 Aug; 1801 (8) :831-8. PubMed PMID:20497909.
Lee EJ, Woo MS, Moon PG, Baek MC, Choi IY, Kim WK, Junn E, Kim HS. Alpha-synuclein activates microglia by inducing the expressions of matrix metalloproteinases and the subsequent activation of protease-activated receptor-1. J Immunol. 2010 Jul 1; 185 (1) :615-23. PubMed PMID:20511551.
Bruce-Keller AJ, Gupta S, Parrino TE, Knight AG, Ebenezer PJ, Weidner AM, LeVine H 3rd, Keller JN, Markesbery WR. NOX activity is increased in mild cognitive impairment. Antioxid Redox Signal. 2010 Jun 15; 12 (12) :1371-82. PubMed PMID:19929442; PubMed Central PMCID: PMC2864654.
Liu J, Shi M, Hong Z, Zhang J, Bradner J, Quinn T, Beyer RP, Mcgeer PL, Chen S, Zhang J. Identification of ciliary neurotrophic factor receptor alpha as a mediator of neurotoxicity induced by alpha-synuclein. Proteomics. 2010 Jun; 10 (11) :2138-50. PubMed PMID:20340160; PubMed Central PMCID: PMC3013276.
Yu C, Nwabuisi-Heath E, Laxton K, Ladu MJ. Endocytic pathways mediating oligomeric Abeta42 neurotoxicity. Mol Neurodegener. 2010 May 17; 5:19. PubMed PMID:20478062; PubMed Central PMCID: PMC2881055.
Lee do Y, Lee KS, Lee HJ, Kim do H, Noh YH, Yu K, Jung HY, Lee SH, Lee JY, Youn YC, Jeong Y, Kim DK, Lee WB, Kim SS. Activation of PERK signaling attenuates Abeta-mediated ER stress. PLoS One. 2010 May 5; 5 (5) :e10489. PubMed PMID:20463975; PubMed Central PMCID: PMC2864758.
Hartz AM, Miller DS, Bauer B. Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease. Mol Pharmacol. 2010 May; 77 (5) :715-23. PubMed PMID:20101004; PubMed Central PMCID: PMC2872973.
Lecanu L, Tillement L, McCourty A, Rammouz G, Yao W, Greeson J, Papadopoulos V. Dimethyl-carbamic acid 2,3-Bis-Dimethylcarbamoyloxy-6-(4-Ethyl-Piperazine-1-Carbonyl)-phenyl ester: a novel multi-target therapeutic approach to neuroprotection. Med Chem. 2010 May 1; 6 (3) :123-40. PubMed PMID:20438444.
Taylor M, Moore S, Mayes J, Parkin E, Beeg M, Canovi M, Gobbi M, Mann DM, Allsop D. Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease. Biochemistry. 2010 Apr 20; 49 (15) :3261-72. PubMed PMID:20230062.
Narasingappa RB, Prahalad RK, Mannar SS, Sathyanarayana RT, Hanumanthappa BK, Jagannatha RK. Molecular studies on Abeta(42) induced genomic instability in aged rabbit brain. Neurochem Int. 2010 Apr; 56 (5) :655-62. PubMed PMID:20117159.
Bohoyo D, Le Potier I, Rivière C, Klafki H, Wiltfang J, Taverna M. A quantitative CE method to analyse tau protein isoforms using coated fused silica capillaries. J Sep Sci. 2010 Apr; 33 (8) :1090-8. PubMed PMID:20187030.
Kinoshita M, Nakatsuji Y, Kimura T, Moriya M, Takata K, Okuno T, Kumanogoh A, Kajiyama K, Yoshikawa H, Sakoda S. Anti-aquaporin-4 antibody induces astrocytic cytotoxicity in the absence of CNS antigen-specific T cells. Biochem Biophys Res Commun. 2010 Mar 26; 394 (1) :205-10. PubMed PMID:20188706.
Luheshi LM, Hoyer W, de Barros TP, van Dijk Härd I, Brorsson AC, Macao B, Persson C, Crowther DC, Lomas DA, Ståhl S, Dobson CM, Härd T. Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo. PLoS Biol. 2010 Mar 16; 8 (3) :e1000334. PubMed PMID:20305716; PubMed Central PMCID: PMC2838747.
Soscia SJ, Kirby JE, Washicosky KJ, Tucker SM, Ingelsson M, Hyman B, Burton MA, Goldstein LE, Duong S, Tanzi RE, Moir RD. The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide. PLoS One. 2010 Mar 3; 5 (3) :e9505. PubMed PMID:20209079; PubMed Central PMCID: PMC2831066.
Hong Z, Shi M, Chung KA, Quinn JF, Peskind ER, Galasko D, Jankovic J, Zabetian CP, Leverenz JB, Baird G, Montine TJ, Hancock AM, Hwang H, Pan C, Bradner J, Kang UJ, Jensen PH, Zhang J. DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease. Brain. 2010 Mar; 133 (Pt 3) :713-26. PubMed PMID:20157014; PubMed Central PMCID: PMC2842513.
Kerr ML, Gasperini R, Gibbs ME, Hou X, Shepherd CE, Strickland DK, Foa L, Lawen A, Small DH. Inhibition of Abeta aggregation and neurotoxicity by the 39-kDa receptor-associated protein. J Neurochem. 2010 Mar; 112 (5) :1199-209. PubMed PMID:20002523.
Li QY, Gordon MN, Chackerian B, Alamed J, Ugen KE, Morgan D. Virus-like peptide vaccines against Abeta N-terminal or C-terminal domains reduce amyloid deposition in APP transgenic mice without addition of adjuvant. J Neuroimmune Pharmacol. 2010 Mar; 5 (1) :133-42. PubMed PMID:20066498.
Magparangalan DP, Garrett TJ, Drexler DM, Yost RA. Analysis of large peptides by MALDI using a linear quadrupole ion trap with mass range extension. Anal Chem. 2010 Feb 1; 82 (3) :930-4. PubMed PMID:20063857.
Bailey JA, Lahiri DK. A novel effect of rivastigmine on pre-synaptic proteins and neuronal viability in a neurodegeneration model of fetal rat primary cortical cultures and its implication in Alzheimer's disease. J Neurochem. 2010 Feb; 112 (4) :843-53. PubMed PMID:19912467; PubMed Central PMCID: PMC2881332.
Kim WS, Bhatia S, Elliott DA, Agholme L, Kågedal K, McCann H, Halliday GM, Barnham KJ, Garner B. Increased ATP-binding cassette transporter A1 expression in Alzheimer's disease hippocampal neurons. J Alzheimers Dis. 2010 Jan; 21 (1) :193-205. PubMed PMID:20413849.
Agholme L, Lindström T, Kågedal K, Marcusson J, Hallbeck M. An in vitro model for neuroscience: differentiation of SH-SY5Y cells into cells with morphological and biochemical characteristics of mature neurons. J Alzheimers Dis. 2010; 20 (4) :1069-82. PubMed PMID:20413890.
Li Y, Duffy KB, Ottinger MA, Ray B, Bailey JA, Holloway HW, Tweedie D, Perry T, Mattson MP, Kapogiannis D, Sambamurti K, Lahiri DK, Greig NH. GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease. J Alzheimers Dis. 2010; 19 (4) :1205-19. PubMed PMID:20308787; PubMed Central PMCID: PMC2948479.
Hou X, Small DH, Aguilar MI. Surface plasmon resonance spectroscopy in determination of the interactions between amyloid beta proteins (Abeta) and lipid membranes. Methods Mol Biol. 2010; 627:225-35. PubMed PMID:20217625.
Jan A, Hartley DM, Lashuel HA. Preparation and characterization of toxic Abeta aggregates for structural and functional studies in Alzheimer's disease research. Nat Protoc. 2010; 5 (6) :1186-209. PubMed PMID:20539293.
Tremblay MA, Acker CM, Davies P. Tau phosphorylated at tyrosine 394 is found in Alzheimer's disease tangles and can be a product of the Abl-related kinase, Arg. J Alzheimers Dis. 2010; 19 (2) :721-33. PubMed PMID:20110615.
Hu X, Crick SL, Bu G, Frieden C, Pappu RV, Lee JM. Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20324-9. Epub 2009 Nov 12. PubMed PMID: 19910533; PubMed Central PMCID: PMC2787156.
Ray B, Bailey JA, Sarkar S, Lahiri DK. Molecular and immunocytochemical characterization of primary neuronal cultures from adult rat brain: Differential expression of neuronal and glial protein markers. J Neurosci Methods. 2009 Nov 15;184(2):294-302. Epub 2009 Aug 29. PubMed PMID: 19720084.
Adamczyk A, Czapski GA, Ka?mierczak A, Strosznajder JB. Effect of N-methyl-D-aspartate (NMDA) receptor antagonists on alpha-synuclein-evoked neuronal nitric oxide synthase activation in the rat brain. Pharmacol Rep. 2009 Nov-Dec;61(6):1078-85. PubMed PMID: 20081243.
Alper BJ, Rowse JW, Schmidt WK. Yeast Ste23p shares functional similarities with mammalian insulin-degrading enzymes. Yeast. 2009 Nov;26(11):595-610. PubMed PMID: 19750477.
Ran C, Xu X, Raymond SB, Ferrara BJ, Neal K, Bacskai BJ, Medarova Z, Moore A. Design, synthesis, and testing of difluoroboron-derivatized curcumins as near-infrared probes for in vivo detection of amyloid-beta deposits. J Am Chem Soc. 2009 Oct 28;131(42):15257-61. PubMed PMID: 19807070; PubMed Central PMCID: PMC2784241.
Lambracht-Washington D, Qu BX, Fu M, Eagar TN, Stüve O, Rosenberg RN. DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model. JAMA. 2009 Oct 28;302(16):1796-802. PubMed PMID: 19861672.
Abdul HM, Sama MA, Furman JL, Mathis DM, Beckett TL, Weidner AM, Patel ES, Baig I, Murphy MP, LeVine H 3rd, Kraner SD, Norris CM. Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling. J Neurosci. 2009 Oct 14;29(41):12957-69. PubMed PMID: 19828810; PubMed Central PMCID: PMC2782445.
Parihar MS, Parihar A, Fujita M, Hashimoto M, Ghafourifar P. Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells. Int J Biochem Cell Biol. 2009 Oct;41(10):2015-24. Epub 2009 May 19. PubMed PMID: 19460457.
Shah SB, Nolan R, Davis E, Stokin GB, Niesman I, Canto I, Glabe C, Goldstein LS. Examination of potential mechanisms of amyloid-induced defects in neuronal transport. Neurobiol Dis. 2009 Oct;36(1):11-25. Epub 2009 Jun 1. PubMed PMID: 19497367.
Peruzzi PP, Lawler SE, Senior SL, Dmitrieva N, Edser PA, Gianni D, Chiocca EA, Wade-Martins R. Physiological transgene regulation and functional complementation of a neurological disease gene deficiency in neurons. Mol Ther. 2009 Sep;17(9):1517-26. Epub 2009 Apr 7. PubMed PMID: 19352323; PubMed Central PMCID: PMC2835262.
Zuo P, Qu W, Cooper RN, Goyer RA, Diwan BA, Waalkes MP. Potential role of alpha-synuclein and metallothionein in lead-induced inclusion body formation. Toxicol Sci. 2009 Sep;111(1):100-8. Epub 2009 Jun 19. PubMed PMID: 19542206; PubMed Central PMCID: PMC2726298.
Knowles JK, Rajadas J, Nguyen TV, Yang T, LeMieux MC, Vander Griend L, Ishikawa C, Massa SM, Wyss-Coray T, Longo FM. The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivo. J Neurosci. 2009 Aug 26;29(34):10627-37. PubMed PMID: 19710315; PubMed Central PMCID: PMC2771439.
Jiang D, Li X, Williams R, Patel S, Men L, Wang Y, Zhou F. Ternary complexes of iron, amyloid-beta, and nitrilotriacetic acid: binding affinities, redox properties, and relevance to iron-induced oxidative stress in Alzheimer's disease. Biochemistry. 2009 Aug 25;48(33):7939-47. PubMed PMID: 19601593; PubMed Central PMCID: PMC2757041.
Darreh-Shori T, Modiri N, Blennow K, Baza S, Kamil C, Ahmed H, Andreasen N, Nordberg A. The apolipoprotein E varepsilon4 allele plays pathological roles in AD through high protein expression and interaction with butyrylcholinesterase. Neurobiol Aging. 2009 Aug 25. [Epub ahead of print] PubMed PMID: 19713000.
Aslund A, Sigurdson CJ, Klingstedt T, Grathwohl S, Bolmont T, Dickstein DL, Glimsdal E, Prokop S, Lindgren M, Konradsson P, Holtzman DM, Hof PR, Heppner FL, Gandy S, Jucker M, Aguzzi A, Hammarström P, Nilsson KP. Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses. ACS Chem Biol. 2009 Aug 21;4(8):673-84. PubMed PMID: 19624097.
Park YH, Kim YJ, Son IH, Yang HD. Inhibition of beta-amyloid(1-40) Peptide Aggregation and Neurotoxicity by Citrate. Korean J Physiol Pharmacol. 2009 Aug;13(4):273-9. Epub 2009 Aug 31. PubMed PMID: 19885010; PubMed Central PMCID: PMC2766705.
Lee JH, Kang DY, Kim SU, Yea CH, Oh BK, Choi JW. Electrical detection of beta-amyloid (1-40) using scanning tunneling microscopy. Ultramicroscopy. 2009 Jul;109(8):923-8. Epub 2009 Mar 19. PubMed PMID: 19345496.
Wilcock DM, Gharkholonarehe N, Van Nostrand WE, Davis J, Vitek MP, Colton CA. Amyloid reduction by amyloid-beta vaccination also reduces mouse tau pathology and protects from neuron loss in two mouse models of Alzheimer's disease. J Neurosci. 2009 Jun 24;29(25):7957-65. Erratum in: J Neurosci. 2010 Jan 20;30(3):1197-8. PubMed PMID: 19553436; PubMed Central PMCID: PMC2871319.
Chanthamontri C, Liu J, McLuckey SA. Charge State Dependent Fragmentation of Gaseous alpha-Synuclein Cations via Ion Trap and Beam-Type Collisional Activation. Int J Mass Spectrom. 2009 Jun 1;283(1-3):9-16. PubMed PMID: 20160958; PubMed Central PMCID: PMC2759116.
Luk C, Giovannoni G, Williams DR, Lees AJ, de Silva R. Development of a sensitive ELISA for quantification of three- and four-repeat tau isoforms in tauopathies. J Neurosci Methods. 2009 May 30;180(1):34-42. Epub 2009 Mar 5. PubMed PMID: 19427527.
Ma G, Liu J, Fu L, Yan EC. Probing water and biomolecules at the air-water interface with a broad bandwidth vibrational sum frequency generation spectrometer from 3800 to 900 cm(-1). Appl Spectrosc. 2009 May;63(5):528-37. PubMed PMID: 19470209.
Patil SM, Xu S, Sheftic SR, Alexandrescu AT. Dynamic alpha-helix structure of micelle-bound human amylin. J Biol Chem. 2009 May 1;284(18):11982-91. Epub 2009 Feb 24. PubMed PMID: 19244249; PubMed Central PMCID: PMC2673267.
Alper BJ, Schmidt WK. A capillary electrophoresis method for evaluation of Abeta proteolysis in vitro. J Neurosci Methods. 2009 Mar 30;178(1):40-5. Epub 2008 Nov 21. PubMed PMID: 19071160.
Zhao L, Lin S, Bales KR, Gelfanova V, Koger D, Delong C, Hale J, Liu F, Hunter JM, Paul SM. Macrophage-mediated degradation of beta-amyloid via an apolipoprotein E isoform-dependent mechanism. J Neurosci. 2009 Mar 18;29(11):3603-12. PubMed PMID: 19295164.
Lee HK, Kumar P, Fu Q, Rosen KM, Querfurth HW. The insulin/Akt signaling pathway is targeted by intracellular beta-amyloid. Mol Biol Cell. 2009 Mar;20(5):1533-44. Epub 2009 Jan 14. PubMed PMID: 19144826; PubMed Central PMCID: PMC2649265.
Momeni P, Pittman A, Lashley T, Vandrovcova J, Malzer E, Luk C, Hulette C, Lees A, Revesz T, Hardy J, de Silva R. Clinical and pathological features of an Alzheimer's disease patient with the MAPT Delta K280 mutation. Neurobiol Aging. 2009 Mar;30(3):388-93. Epub 2007 Aug 27. PubMed PMID: 17723255; PubMed Central PMCID: PMC2666148.
Vintém AP, Henriques AG, da Cruz E Silva OA, da Cruz E Silva EF. PP1 inhibition by Abeta peptide as a potential pathological mechanism in Alzheimer's disease. Neurotoxicol Teratol. 2009 Mar-Apr;31(2):85-8. Epub 2008 Nov 12. PubMed PMID: 19028567.
28: Liu Q, Huang Y, Xue F, Simard A, DeChon J, Li G, Zhang J, Lucero L, Wang M, Sierks M, Hu G, Chang Y, Lukas RJ, Wu J. A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides. J Neurosci. 2009 Jan 28;29(4):918-29. PubMed PMID: 19176801; PubMed Central PMCID: PMC2857410.
Näsström T, Wahlberg T, Karlsson M, Nikolajeff F, Lannfelt L, Ingelsson M, Bergström J. The lipid peroxidation metabolite 4-oxo-2-nonenal cross-links alpha-synuclein causing rapid formation of stable oligomers. Biochem Biophys Res Commun. 2009 Jan 23;378(4):872-6. Epub 2008 Dec 12. PubMed PMID: 19070597.
Park HM, Kim JA, Kwak MK. Protection against amyloid beta cytotoxicity by sulforaphane: role of the proteasome. Arch Pharm Res. 2009 Jan;32(1):109-15. Epub 2009 Jan 29. PubMed PMID: 19183883.
Kang DY, Lee JH, Oh BK, Choi JW. Ultra-sensitive immunosensor for beta-amyloid (1-42) using scanning tunneling microscopy-based electrical detection. Biosens Bioelectron. 2009 Jan 1;24(5):1431-6. Epub 2008 Aug 22. PubMed PMID: 18829296.
Adamczyk A, Ka?mierczak A. Alpha-synuclein inhibits poly (ADP-ribose) polymerase-1 (PARP-1) activity via NO-dependent pathway. Folia Neuropathol. 2009;47(3):247-51. PubMed PMID: 19813144.
Yin S, Loo JA. Mass spectrometry detection and characterization of noncovalent protein complexes. Methods Mol Biol. 2009;492:273-82. PubMed PMID: 19241039.
Englund H, Degerman Gunnarsson M, Brundin RM, Hedlund M, Kilander L, Lannfelt L, Pettersson FE. Oligomerization partially explains the lowering of Abeta42 in Alzheimer's disease cerebrospinal fluid. Neurodegener Dis. 2009;6(4):139-47. Epub 2009 Jun 12. PubMed PMID: 19521063.
Rahimi. F., Shanmugam, A., Bitan, G. (2008) Structure-Function Relationships of Pre-Fibrillar Protein Assemblies in Alzheimer's disease and Related Disorders. Current Alzheimer Research; 5(3):319-341.
Kerrigan., Talitha L., Atkinson, L., Peers, C., Pearson, H. A. (2008) Modulation of 'A'-type K+ current by rodent and human forms of amyloid [beta] protein. Neuroreport; 19(8):839-843.
Girigoswami, K., Hee K.S., Ryu, J., Park, C.B. (2008) A synthetic amyloid lawn system for high-throughput analysis of amyloid toxicity and drug screening. Biomaterials; 29:2813-2819.
Ryu, J., Kanapathipillai, M., Lentzen, M., Park, C.B. (2008) Inhibition of β-amyloid peptide aggregation and neurotoxicity by α-d-mannosylglycerate, a natural extremolyte. Peptides; 29: 578-584.
Garai, K., Sahoo, B., Sengupta, B., Maiti, S (2008) Quasihomogeneous nucleation of amyloid beta yields numerical bounds for the critical radius, the surface tension, and the free energy barrier for nucleus formation. J. Chem. Phys; 128, 045102.
Kasai, T., Tokuda, T., Yamaguchi, N., Watanabe, Y., Kametani, F., Nakagawa, M., Mizuno, T. (2008) Cleavage of normal and pathological forms of α-synuclein by neurosin in vitro. Neuroscience Letters: 436, 52-56
Skoglund, L., Viitanen, M., Kalimo, H., Lannfelt, L., Ingelsson, M., Glaser, A., Herva, R. (2008) The tau S305S mutation causes frontotemporal dementia with parkinsonism. European Journal of Neurology; 15(2): 156-161.
Vello, T., Karafin, A., Palumaa, P. (2008) Binding of zinc (II) and copper (II) to the full-length Alzheimer's amyloid-[beta] peptide. Journal of Neurochemistry; 104(5): 1249-1259.
Udan, M.L.D., Deepa, A., Nikkilina, C.R., Nichols, M.R. (2008) Toll-like receptors 2 and 4 mediate A[beta](1-42) activation of the innate immune response in a human monocytic cell line. Journal of Neurochemistry; 104(2): 524-533.
Hübinger, G., Geis, S., LeCorre, S., Mühlbacher, S., Gordon, S., Fracasso, R.P., Hoffman, F ., Ferrand, S ., Klafki, H.W ., Roder, H.M . (2008) Inhibition of PHF-like Tau Hyperphosphorylation in SH-SY5Y Cells and Rat Brain Slices by K252a. Journal of Alzheimer's Disease; 13(3): 281-294.
Deborah, J.T., Stephen, P.B., David, P.S., Giuseppe, D.C., Jeffrey, B., Mark, G.H., Colin L.M., Roberto, C., Kevin. J.B. (2008) Stabilization of Neurotoxic Soluble β-Sheet-Rich Conformations of the Alzheimer's Disease Amyloid-β Peptide. Biophysical Journal; 94: 2752-2766.
Hoyer, W., Gronwall, C., Jonsson, A., Stahl, S., Hard, T. (2008) Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation. PNAS; 105(13):5099-5014.
LIU, L., Hiroaki, K., Ian, M.V.J., Paul, A.H. (2008) Promotion of Amyloid β Protein Misfolding and Fibrillogenesis by a Lipid Oxidation Product. Journal of molecular biology; 377(4): 1236-1250.
Burdo, J.R., Chen, Q., Calcutt, N.A., Schubert, D. (2008) The pathological interaction between diabetes and presymptomatic Alzheimer's disease. Neurobiol Aging; March 26.
Wu, W.H., Sun, X., Ye, P.Y., Hu, J., Zhao, L., Liu, Q., Zhao, Y.F., Li, Y.M. (2008) TiO2 nanoparticles promote β-amyloid fibrillation in vitro. Biochemical and Biophysical Research Communications; 373(2):315-318.
Verpillota, R., Ottob, M., Klafkic, H., Taverna, M. (2008) Simultaneous analysis by capillary electrophoresis of five amyloid peptides as potential biomarkers of Alzheimer's disease. Journal of Chromatography A; 1214(1-2):157-164.
Burton, C.R., Meredith, J.E., Barten, J.M., Goldstein, M.E., Krause, C.M., Kieras, C.J., Stern, A.M., Seiffert, D.A., Zaczek, R., Albright, C.F., Toyn, J.H. (2008) The Amyloid-β Rise and {gamma}-Secretase Inhibitor Potency Depend on the Level of Substrate Expression*Formula. J. Biol. Chem.; 283(34): 22992-23003.
Näsström, T., Wahlberg, T., Karlsson, M., Nikolajeff, F., Lannfelt, L., Ingelsson, M., Bergström, J. (2008) The lipid peroxidation metabolite 4-oxo-2-nonenal cross-links α-synuclein causing rapid formation of stable oligomers. Biochemical and Biophysical Research Communications; 378 (4): 872-876.
Vintém, A.P.B., Henriques, A.G., CruzeSilva, O.A., Cruz E Silva, O.E. (2008) PP1 inhibition by Aβ peptide as a potential pathological mechanism in Alzheimer's disease. Neurotoxicology and Teratology, 31(2): 85-88
Hu, M., Waring, J.F., Gopalakrishnan, M., Li, J. (2008) Role of GSK-3β activation and α7 nAChRs in Aβ1–42-induced tau phosphorylation in PC12 cells. Journal of Neurochemistry; 106(3): 1371-1377.
Ghosha, J.G., Houcka, S.A., Clarka, J.I. (2008) Interactive sequences in the molecular chaperone, human αB crystallin modulate the fibrillation of amyloidogenic proteins. The International Journal of Biochemistry & Cell Biology; 40(5): 954-967.
Kanga, D.Y., Leea, J.H., Oha, B.K., Choia, J.W. (2009) Ultra-sensitive immunosensor for β-amyloid (1–42) using scanning tunneling microscopy-based electrical detection. Biosensors and Bioelectronics; 24 (5): 1431-1436.
Lya, T., Julian, R.R. (2008) Protein–Metal Interactions of Calmodulin and α-Synuclein Monitored by Selective Noncovalent Adduct Protein Probing Mass Spectrometry. Journal of the American Society for Mass Spectrometry; 19(11): 1663-1672.
Parihar, M.S., Parihar, A.,Fujita, M., Hashimoto, M., Ghafourifar, P. (2008) Mitochondrial association of alpha-synuclein causes oxidative stress. Journal of the Cellular and Molecular Life Sciences; 65(7-8): 1272-1284.
Sontag, J.M., Viyada N.C., Montgomery, L.,Arning, E., Bottiglieri, T., Sontag, E. (2008) Folate Deficiency Induces In Vitro and Mouse Brain Region-Specific Downregulation of Leucine Carboxyl Methyltransferase-1 and Protein Phosphatase 2A B{alpha} Subunit Expression That Correlate with Enhanced Tau Phosphorylation. The Journal of Neuroscience; 28(45):11477-11487.
Petersen, C.A., Alikhani, N., Behbahani, H., Wiehager, B., Pavlov, P.F., Alafuzoff, I., Leinonen, V., Ito, A., Winblad, B., Ankarcrona, M. (2008) The amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae. PNAS; 105 (35): 13145-13150.
Macao, B., Hoyer, W., Sandberg, A., Brorsson, C., Dobson, C.M., Härd, T. (2008) Recombinant amyloid beta-peptide production by coexpression with an affibody ligand. BMC Biotechnology; 8:82 doi:10.1186/1472-6750-8-82.
Jiang, Q., Lee, C., Mandrekar, S., Wilkinson, B., Cramer, P., Zelcer, N., Mann, K., Lamb, B., Willson, T., Collins, J. (2008) ApoE Promotes the Proteolytic Degradation of Aβ. Neuron; 58(5): 681-693.
Abramowski, D., Wiederhold, K-H., Furrer, U., Jaton, A-L., Neuenschwander, A., Runser, M-J., Danner, S., Reichwald, J., Ammaturo, D., Staab, D., Stoeckli, M., Rueeger, H., Neumann, U., Staufenbiel, M. (2008) Dynamics of Aβ Turnover and Deposition in Different β-Amyloid Precursor Protein Transgenic Mouse Models Following {gamma}-Secretase Inhibition formula. Journal of Pharmacology and Experimental Therapeutics; 327:411-424.
Wieneke J.A., Abdo, W.F., Melis, R., Williams, S., Bloem, B.R., Verbeek, M.M. (2008) A more efficient enzyme-linked immunosorbent assay for measurement of α-synuclein in cerebrospinal fluid. Journal of Neuroscience Methods; 168(1): 182-185.
Walker, D.G., Dalsing-Hernandez, J.E., Lue, L.F. (2008) Human postmortem brain-derived cerebrovascular smooth muscle cells express all genes of the classical complement pathway: A potential mechanism for vascular damage in cerebral amyloid angiopathy and Alzheimer's disease. Microvascular Research; 75(3): 411-419.
Costa, R., Ferreira-da-Silva, F., Saraiva, M.J., Cardoso, I. (2008) Transthyretin Protects against A-Beta Peptide Toxicity by Proteolytic Cleavage of the Peptide: A Mechanism Sensitive to the Kunitz Protease Inhibitor. PLoS ONE; 3(8): E2899.
Thomas. L.K., Thomas. B.L., Maralyssa. A.B., Patrick. C., Fraering., Narlawar. R., Maharvi. G.M., Healy.B., Robert. C., Alfred T., Welzel, R.W., Price., Moore. B., Rangachari. V., Cusack. V., Jason. E., Karen. J-W., Verbeeck. C., Yager. D., Christopher. E., Ye. W., Sagi. S., Barbara. A., Cottrell., Torpey. J., Rosenberry. L.T., Fauq. A., Michael. S.W., Schmidt. B.,Walsh. D.M., Edward. H.K., Todd. E.G. (2008) Substrate-targeting γ-secretase modulators. Nature; 453: 925-929.
Hoyer, W., Hard, T (2008) Interaction of Alzheimer’s Aβ Peptide with an Engineered Binding Protein-Thermodynamics and Kinetics of Coupled Folding–Binding. Journal of Molecular Biology; 378(25): 398-411.
Jiang, Q., Daniel Lee, C.Y., Mandrekar, S., Wilkinson, B., Cramer, P., Zelcer, N., Mann, K., Lamb, B., Willson, T.M., Collins, J.L., Richardson, J.C., Smith, J.D., Comery, T.A., Riddell, D., Holtzman, D., Tontonoz, P., Landreth, G.E. (2008) ApoE Promotes the Proteolytic Degradation of Aβ. Neuron; 58(5): 681-693.
Jacobsa, A., Garga, H., Viarda, M., Raviva, Y., Puria, A., Blumenthala, R. (2008) HIV-1 envelope glycoprotein-mediated fusion and pathogenesis: Implications for therapy and vaccine developmentstar. Vaccine; 26(24): 3026-3035.
Thoennesa, S., Lia, Z.N., Leea, B.J., Langleya, W.A., Skehelb, J.J., Russellc, R.J., Steinhauera, D.A. (2008) Analysis of residues near the fusion peptide in the influenza hemagglutinin structure for roles in triggering membrane fusion. Virology; 370(2): 403-414.
Leaman, Douglas W. (2008) Recent progress in oligonucleotide therapeutics: antisense to aptamers. Expert Opinion on Drug Discovery; 3(9): 997-1009.
Li, Z.N., Lee, B.J., Langley, W.A., Bradley, K.C., Russell, R.J., Steinhauer, D.A. (2008) Length Requirements for Membrane Fusion of Influenza Virus Hemagglutinin Peptide Linkers to Transmembrane or Fusion Peptide Domains {triangledown}. Journal of Virology; 82(13): 6337-6348.
Wathen, B., Jia, Z. (2008) Local and Nonlocal Environments around Cis Peptides. J. Proteome Res.;7(01): 145-153.
McHugh, L., Arthur, J.W. (2008) Computational Methods for Protein Identification from Mass Spectrometry Data. PLoS Comput Biol; 4(2): E12.